- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Interventions
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Device
- Lead sponsor
- Teoxane SA
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 4
- States / cities
- Encinitas, California • West Palm Beach, Florida • Chapel Hill, North Carolina + 1 more
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Nasolabial Folds, Wrinkles
- Interventions
- TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines
- Device
- Lead sponsor
- Teoxane SA
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 5
- States / cities
- Birmingham, Alabama • Beverly Hills, California • Santa Monica, California + 2 more
- Conditions
- Correction of Nasolabial Folds
- Interventions
- Subdermal Injection, Artiste Assisted Injection System
- Procedure · Device
- Lead sponsor
- TKL Research, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 3
- States / cities
- New York, New York • Houston, Texas • Spokane, Washington
- Conditions
- Nasolabial Fold Wrinkles
- Interventions
- CelluJuve®
- Device
- Lead sponsor
- Spiderwort Biotechnologies Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Coral Gables, Florida
- Conditions
- Nasolabial Folds
- Interventions
- tetracaine 7% / lidocaine 7% cream (Pliaglis® Cream), benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Drug
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008
- U.S. locations
- 4
- States / cities
- Aventura, Florida • West Palm Beach, Florida • New York, New York + 1 more
- Conditions
- Facial Wrinkles
- Interventions
- Belotero, Zyplast
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 118 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2008
- U.S. locations
- 6
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 3 more
- Conditions
- Nasolabial Folds
- Interventions
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 2
- States / cities
- Rockville, Maryland • New York, New York
- Conditions
- Nasolabial Folds
- Interventions
- Platelet rich fibrin matrix
- Biological
- Lead sponsor
- The New York Eye & Ear Infirmary
- Other
- Eligibility
- 25 Years to 75 Years · Female only
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Chappaqua, New York
- Conditions
- Dermatological Non-Disease
- Interventions
- Princess Filler Lidocaine
- Device
- Lead sponsor
- Croma-Pharma GmbH
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 295 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 11
- States / cities
- Birmingham, Alabama • Beverly Hills, California • San Diego, California + 8 more
- Conditions
- Nasolabial Folds
- Interventions
- Radiesse® Injectable Dermal Filler
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Chevy Chase, Maryland • Ypsilanti, Michigan + 2 more
- Conditions
- Rhytids
- Interventions
- Restylane
- Drug
- Lead sponsor
- Medicis Aesthetics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2009
- U.S. locations
- 3
- States / cities
- Coral Gables, Florida • Chicago, Illinois • White Plains, New York
- Conditions
- Face; Atrophy
- Interventions
- DA-13-007 right with left side Sculptra left side, DA-13-007 left with left side Sculptra right side
- Device
- Lead sponsor
- DermAvance
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 161 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2018
- U.S. locations
- 4
- States / cities
- Bradenton, Florida • Coral Gables, Florida • Carmel, Indiana + 1 more
- Conditions
- Correction of Nasolabial Folds and Lip Augmentation
- Interventions
- PREVELLE Shape, Restylane
- Device
- Lead sponsor
- Mentor Worldwide, LLC
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Santa Barbara, California
- Conditions
- Moderate to Severe Nasolabial Folds
- Interventions
- JUVEDERM VOLIFT® XC, Control
- Device
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 3 more
- Conditions
- Facial Rhytides, Crow's Feet Lines, Glabellar Lines, Nasolabial Fold
- Interventions
- onabotulinumtoxinA, bimatoprost ophthalmic solution 0.03%, JUVÉDERM® ULTRA XC, JUVÉDERM® ULTRA PLUS XC, JUVÉDERM® VOLUMA® XC
- Biological · Drug · Device
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 35 Years to 65 Years
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Nasolabial Folds
- Interventions
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 5
- States / cities
- Scottsdale, Arizona • Solana Beach, California • Bradenton, Florida + 2 more
- Conditions
- Nasolabial Folds
- Interventions
- TAT4 Gel, Matching placebo
- Drug
- Lead sponsor
- Topokine Therapeutics, Inc.
- Industry
- Eligibility
- 35 Years to 60 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Facial Wrinkles
- Interventions
- Aquamid, Restylane
- Device
- Lead sponsor
- Contura
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 315 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- White Plains, New York
- Conditions
- Nasolabial Folds
- Interventions
- Belotero®
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 117 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 5 more
- Conditions
- Nasolabial Fold Correction
- Interventions
- Revanesse Ultra+ (with lidocaine), Revanesse Ultra
- Device
- Lead sponsor
- Prollenium Medical Technologies Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Nasolabial Fold, Cheek Augmentation
- Interventions
- SMI-01
- Device
- Lead sponsor
- Sofregen Medical, Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Encinitas, California • Miami, Florida
- Conditions
- Facial Wrinkles
- Interventions
- NADGL
- Device
- Lead sponsor
- Genzyme, a Sanofi Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Nasolabial Folds
- Interventions
- Restylane and Restylane-L
- Device
- Lead sponsor
- Medicis Global Service Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 3
- States / cities
- Coral Gables, Florida • Hunt Valley, Maryland • Mount Kisco, New York
- Conditions
- Bilateral Nasolabial Fold Wrinkles
- Interventions
- Autologous Human Fibroblasts (azficel-T), Placebo
- Biological
- Lead sponsor
- Castle Creek Biosciences, LLC.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 218 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 6
- States / cities
- Beverly Hills, California • San Diego, California • Snellville, Georgia + 3 more