- Conditions
- Nasolabial Folds
- Interventions
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 2
- States / cities
- Rockville, Maryland • New York, New York
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Showing 1–24
of 46
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Nasolabial Folds
- Interventions
- Belotero®
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 117 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 5 more
- Conditions
- Wrinkle
- Interventions
- Defyne Treatment in Nasolabial Fold, RHA3 Treatment in Nasolabial Fold
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Santa Rosa Beach, Florida
- Conditions
- Nasolabial Fold Correction
- Interventions
- Revanesse Ultra+ (with lidocaine), Revanesse Ultra
- Device
- Lead sponsor
- Prollenium Medical Technologies Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Nasolabial Folds
- Interventions
- Ellanse S, Calcium Hydroxylapatite-based filler
- Device
- Lead sponsor
- AQTIS Medical B.V.
- Other
- Eligibility
- 22 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 7
- States / cities
- Scottsdale, Arizona • Encino, California • Westport, Connecticut + 4 more
- Conditions
- Moderate to Severe Nasolabial Folds
- Interventions
- JUVEDERM VOLIFT® XC, Control
- Device
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 3 more
- Conditions
- Skin Rejuvenation, Skin Quality, Wrinkle, Nasolabial Fold
- Interventions
- PRFM injection, Saline injection
- Procedure
- Lead sponsor
- New York Medical College
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Valhalla, New York
- Conditions
- Nasolabial Folds
- Interventions
- tetracaine 7% / lidocaine 7% cream (Pliaglis® Cream), benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Drug
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008
- U.S. locations
- 4
- States / cities
- Aventura, Florida • West Palm Beach, Florida • New York, New York + 1 more
- Conditions
- Bilateral Nasolabial Fold Wrinkles
- Interventions
- Autologous Human Fibroblasts (azficel-T), Placebo
- Biological
- Lead sponsor
- Castle Creek Biosciences, LLC.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 218 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 6
- States / cities
- Beverly Hills, California • San Diego, California • Snellville, Georgia + 3 more
- Conditions
- Facial Wrinkles
- Interventions
- CosmetaLife, Restylane
- Device
- Lead sponsor
- Cosmeta
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 145 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2008
- U.S. locations
- 5
- States / cities
- Tracy, California • Roswell, Georgia • Chestnut Hill, Massachusetts + 2 more
- Conditions
- Correction of Nasolabial Folds
- Interventions
- Subdermal Injection, Artiste Assisted Injection System
- Procedure · Device
- Lead sponsor
- TKL Research, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 3
- States / cities
- New York, New York • Houston, Texas • Spokane, Washington
- Conditions
- Nasolabial Folds
- Interventions
- Restylane and Restylane-L
- Device
- Lead sponsor
- Medicis Global Service Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 3
- States / cities
- Coral Gables, Florida • Hunt Valley, Maryland • Mount Kisco, New York
- Conditions
- Correction of Nasolabial Folds and Lip Augmentation
- Interventions
- PREVELLE Shape, Restylane
- Device
- Lead sponsor
- Mentor Worldwide, LLC
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Santa Barbara, California
- Conditions
- Nasolabial Folds
- Interventions
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 5
- States / cities
- Scottsdale, Arizona • Solana Beach, California • Bradenton, Florida + 2 more
- Conditions
- Nasolabial Fold Wrinkles
- Interventions
- DL6049 (injectable poly-L-lactic acid)
- Device
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Bilateral Nasolabial Fold Wrinkles
- Interventions
- Autologous Human Fibroblast (azficel-T), Placebo
- Biological
- Lead sponsor
- Castle Creek Biosciences, LLC.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 203 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Newport Beach, California • Coral Gables, Florida + 4 more
- Conditions
- Nasolabial Fold, Facial Wrinkles
- Interventions
- Sculptra Aesthetic, Placebo
- Device · Other
- Lead sponsor
- Sadick Research Group
- Other
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Facial Wrinkles
- Interventions
- CosmoDerm1, Belotero Soft
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 5
- States / cities
- Los Angeles, California • San Francisco, California • New Haven, Connecticut + 2 more
- Conditions
- Skin Manifestations
- Interventions
- GP0116, Active Comparator: FDA approved dermal filler device (RHA 3)
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 186 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 18
- States / cities
- Santa Monica, California • Vista, California • Westport, Connecticut + 14 more
- Conditions
- Nasolabial Fold, Cheek Augmentation
- Interventions
- SMI-01
- Device
- Lead sponsor
- Sofregen Medical, Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Encinitas, California • Miami, Florida
- Conditions
- Facial Wrinkles
- Interventions
- Hylaform, Hylaform Plus (hylan B gel)
- Device
- Lead sponsor
- Genzyme, a Sanofi Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Warren, Michigan • Philadelphia, Pennsylvania
- Conditions
- Facial Wrinkles
- Interventions
- Aquamid, Restylane
- Device
- Lead sponsor
- Contura
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 315 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- White Plains, New York
- Conditions
- Wrinkles
- Interventions
- Elevess
- Device
- Lead sponsor
- Anika Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Boca Raton, Florida • Coral Gables, Florida + 6 more
- Conditions
- Nasolabial Folds
- Interventions
- Sculptra Aesthetic, Lidocaine HCL
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 4
- States / cities
- Scottsdale, Arizona • Bradenton, Florida • Austin, Texas + 1 more