- Conditions
- Wrinkle
- Interventions
- Defyne Treatment in Nasolabial Fold, RHA3 Treatment in Nasolabial Fold
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Santa Rosa Beach, Florida
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 46
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Aging, Pain
- Interventions
- RHA®4 with new anesthetic agent, RHA®4-Lidocaine
- Device
- Lead sponsor
- Teoxane SA
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 3
- States / cities
- Beverly Hills, California • Coral Gables, Florida • Chicago, Illinois
- Conditions
- Nasolabial Fold, Facial Wrinkles
- Interventions
- Sculptra Aesthetic, Placebo
- Device · Other
- Lead sponsor
- Sadick Research Group
- Other
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Nasolabial Folds
- Interventions
- Perlane and Perlane-L
- Device
- Lead sponsor
- Medicis Global Service Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 3
- States / cities
- Coral Gables, Florida • Hunt Valley, Maryland • Mount Cisco, New York
- Conditions
- Nasolabial Fold, Cheek Augmentation
- Interventions
- SMI-01
- Device
- Lead sponsor
- Sofregen Medical, Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Encinitas, California • Miami, Florida
- Conditions
- Nasolabial Fold Wrinkles
- Interventions
- CelluJuve®
- Device
- Lead sponsor
- Spiderwort Biotechnologies Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Coral Gables, Florida
- Conditions
- Nasolabial Folds, Lipoatrophy, Lipodystrophy
- Interventions
- TAT4 Gel concentration A, TAT4 Gel concentration B, Placebo
- Drug
- Lead sponsor
- Topokine Therapeutics, Inc.
- Industry
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Cypress, California
- Conditions
- Facial Wrinkles
- Interventions
- CosmoDerm1, Belotero Soft
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 5
- States / cities
- Los Angeles, California • San Francisco, California • New Haven, Connecticut + 2 more
- Conditions
- Facial Wrinkles at the Nasolabial Folds
- Interventions
- Dermal Gel Extra (DGE), Restylane, EMLA Cream
- Device · Drug
- Lead sponsor
- Genzyme, a Sanofi Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 6
- States / cities
- Birmingham, Alabama • La Jolla, California • Miami Beach, Florida + 3 more
- Conditions
- Nasolabial Fold Wrinkles
- Interventions
- DL6049 (injectable poly-L-lactic acid)
- Device
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Rhytids
- Interventions
- Restylane
- Drug
- Lead sponsor
- Medicis Aesthetics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2009
- U.S. locations
- 3
- States / cities
- Coral Gables, Florida • Chicago, Illinois • White Plains, New York
- Conditions
- Dermatological Non-Disease
- Interventions
- Princess Filler Lidocaine
- Device
- Lead sponsor
- Croma-Pharma GmbH
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 295 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 11
- States / cities
- Birmingham, Alabama • Beverly Hills, California • San Diego, California + 8 more
- Conditions
- Nasolabial Folds, Wrinkles
- Interventions
- TEOSYAL® RHA Ultra Deep
- Device
- Lead sponsor
- Teoxane SA
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 4
- States / cities
- Beverly Hills, California • Bradenton, Florida • Chapel Hill, North Carolina + 1 more
- Conditions
- Nasolabial Folds
- Interventions
- Belotero®
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 117 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 5 more
- Conditions
- Nasolabial Folds
- Interventions
- Platelet rich fibrin matrix
- Biological
- Lead sponsor
- The New York Eye & Ear Infirmary
- Other
- Eligibility
- 25 Years to 75 Years · Female only
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Chappaqua, New York
- Conditions
- Facial Wrinkles
- Interventions
- Belotero, Zyplast
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 118 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2008
- U.S. locations
- 6
- States / cities
- Birmingham, Alabama • Los Angeles, California • San Francisco, California + 3 more
- Conditions
- Facial Wrinkles
- Interventions
- Aquamid, Restylane
- Device
- Lead sponsor
- Contura
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 315 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- White Plains, New York
- Conditions
- Facial Wrinkles
- Interventions
- CosmetaLife, Restylane
- Device
- Lead sponsor
- Cosmeta
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 145 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2008
- U.S. locations
- 5
- States / cities
- Tracy, California • Roswell, Georgia • Chestnut Hill, Massachusetts + 2 more
- Conditions
- Facial Wrinkles
- Interventions
- NADGL
- Device
- Lead sponsor
- Genzyme, a Sanofi Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Correction of Moderate to Severe Nasolabial Folds
- Interventions
- Belotero® Balance with integral lidocaine, Belotero® Balance
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 3
- States / cities
- Washington D.C., District of Columbia • Nashville, Tennessee • Plano, Texas
- Conditions
- Nasolabial Folds
- Interventions
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 2
- States / cities
- Rockville, Maryland • New York, New York
- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Interventions
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Device
- Lead sponsor
- Teoxane SA
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 4
- States / cities
- Encinitas, California • West Palm Beach, Florida • Chapel Hill, North Carolina + 1 more
- Conditions
- Facial Wrinkles
- Interventions
- Belotero®
- Device
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Mitchellville, Maryland • Montclair, New Jersey
- Conditions
- Nasolabial Folds
- Interventions
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Device
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 5
- States / cities
- Scottsdale, Arizona • Solana Beach, California • Bradenton, Florida + 2 more