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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:16 PM EST

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Showing 25–42 of 42 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Necrotising Enterocolitis Neonatal Clear all

Conditions: Premature Birth of Newborn, Enterocolitis, Necrotizing
Interventions: Ampicillin, Gentamicins, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: Up to 6 Hours
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Prematurity, Necrotizing Enterocolitis
Interventions: [5,5,5-2H3]leucine (stable isotope labeled leucine); Biological
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 1 Day to 7 Days
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Necrotizing Enterocolitis, Sepsis
Interventions: Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement; Behavioral
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 0 Years to 96 Hours
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1997
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Infection, Enterocolitis, Necrotizing, Ventilator-associated Pneumonia
Interventions: oropharyngeal mother's milk, oropharyngeal sterile water; Other
Lead sponsor: Endeavor Health; Other
Eligibility: 1 Day to 4 Days
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 5
States / cities: Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more

Conditions: Parenteral Nutrition, Necrotizing Enterocolitis, Digestive System Abnormalities, Cholestasis
Interventions: Remove Mn from PN if evidence of increased brain Mn on MRI; Dietary Supplement
Lead sponsor: Vanderbilt University; Other
Eligibility: 30 Days to 6 Years
Enrollment: 122 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Sepsis, Necrotising Enterocolitis Neonatal
Interventions: No Intervention: Observational Cohort; Other
Lead sponsor: University of Virginia; Other
Eligibility: Not listed
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Necrotizing Enterocolitis, Digestive System Abnormalities, Cholestasis
Interventions: remove Mn from PN if evidence of increased brain Mn on MRI; Dietary Supplement
Lead sponsor: Vanderbilt University; Other
Eligibility: 30 Days to 12 Months
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Enterocolitis, Necrotizing, Premature Infant
Interventions: Bowel Ultrasound; Diagnostic Test
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: Up to 28 Weeks
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
Interventions: Near-infrared spectroscopy (NIRS); Procedure
Lead sponsor: University of Utah; Other
Eligibility: 12 Days to 6 Months
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 3
States / cities: Murray, Utah • Salt Lake City, Utah

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions: Not listed
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 6 Weeks
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 17
States / cities: Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more

Conditions: Congenital Heart Disease, Prematurity, Necrotizing Enterocolitis
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 1 Month
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Infant, Premature, Diseases, Hypoxia, Necrotizing Enterocolitis
Interventions: Near Infrared Spectroscopy; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: Up to 3 Weeks
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions: Ampicillin, Gentamycin, Normal saline; Drug
Lead sponsor: Michael Morowitz; Other
Eligibility: Up to 4 Hours
Enrollment: 359 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 14
States / cities: Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more

Conditions: Necrotizing Enterocolitis
Interventions: STP206, Control; Biological · Other
Lead sponsor: Leadiant Biosciences, Inc.; Industry
Eligibility: 1 Day to 4 Days
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 13
States / cities: Hartford, Connecticut • Sunrise, Florida • Augusta, Georgia + 10 more

Conditions: Transfusions
Interventions: NPO, Control group: continue feedings; Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 3 Days to 6 Months
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Prematurity Complications
Interventions: measurement of intestinal permeability; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: Up to 4 Days
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Necrotizing Enterocolitis, Necrotizing Enterocolitis of Newborn, Sepsis Newborn, Cows Milk Allergy
Interventions: Survey investigating Infant formula feeding in newborns; Dietary Supplement
Lead sponsor: Neuroganics LLC; Industry
Eligibility: 1 Day to 2 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Northglenn, Colorado

Conditions: Enterocolitis, Necrotizing, Bacteremia, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia, Chronic Lung Disease, Ileal Perforation
Interventions: Antibiotic, Gastric fluid, Breast milk, Stool samples, Antibiotics; Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 23 Weeks to 33 Weeks
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Gainesville, Florida

Search by objective public record fields.

A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome

Collaborative Research Group for Necrotizing Enterocolitis

Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants

Oropharyngeal Administration of Mother's Colostrum for Premature Infants (NS-72393-360)

Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children

Integrated Predictive Monitoring for Sepsis and Necrotizing Enterocolitis

Brain Manganese Deposition in High Risk Neonates

NEC Screening Abdominal Radiograph vs Bowel Ultrasound in Preemies

Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus

Observational Study of Surgical Treatment of Necrotizing Enterocolotis

Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease

Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy

NICU Antibiotics and Outcomes Trial

STP206 for the Prevention of Necrotizing Enterocolitis (NEC)

Impact of Feeding on Pro-Inflammatory Cytokine Response in Neonates Receiving a RBC Transfusion

Gut Permeability and Microbiome in Preterm Infants

Infant Formula Feeding and Necrotizing Enterocolitis in Newborns

Antibiotic "Dysbiosis" in Preterm Infants