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ClinicalTrials.gov public records Last synced Nov 10, 2026, 5:48 PM EST

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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Neuro-Degenerative Disease Clear all

Conditions: Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases, Neoplasms, Frailty, Activities of Daily Living, Health-Related Quality of Life, Disability Physical, Neuro-Degenerative Disease, Dementia
Interventions: Comprehensive Multi-System Clinical Screening; Diagnostic Test
Lead sponsor: Longevity Metrics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,000,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2099
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Parkinson Disease, Movement Disorders, Neuro-Degenerative Disease
Interventions: Golf Instruction, Tai Chi Class; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary Progress Multiple Sclerosis (SPMS), Primary Progressive Multiple Sclerosis (PPMS), MS, MS (Multiple Sclerosis), Neuro-Degenerative Disease, Neuro-Degenerative Diseases, Autoimmune
Interventions: C-CAR168; Drug
Lead sponsor: AbelZeta Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 2
States / cities: Gilbert, Arizona • La Jolla, California

Conditions: Alzheimer Disease, Neurodegenerative Diseases
Interventions: Cytology and Immunohistochemistry; Diagnostic Test
Lead sponsor: University of Arkansas; Other
Eligibility: 19 Years to 89 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Friedreich Ataxia
Interventions: Not listed
Lead sponsor: Friedreich's Ataxia Research Alliance; Other
Eligibility: Not listed
Enrollment: 3,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2048
U.S. locations: 9
States / cities: Los Angeles, California • Denver, Colorado • Gainesville, Florida + 6 more

Conditions: Alzheimer Disease, Early Onset, Alzheimer Disease, Alzheimer Disease, Late Onset, Dementia, Alzheimer Type, Logopenic Progressive Aphasia, Primary Progressive Aphasia, Visuospatial/Perceptual Abilities, Posterior Cortical Atrophy, Executive Dysfunction, Corticobasal Degeneration, Ideomotor Apraxia
Interventions: Not listed
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years to 85 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma, Erdheim-Chester Disease, Rosai Dorfman Disease, Neuro-Degenerative Disease, Histiocytic Sarcoma, Histiocytic Disorders, Malignant
Interventions: Cobimetinib; Drug
Lead sponsor: Carl Allen; Other
Eligibility: Not listed
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 12
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Orange, California + 9 more

Conditions: Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type, Dementia Severe
Interventions: Not listed
Lead sponsor: Karen Roberto; Other
Eligibility: 18 Years and older
Enrollment: 275 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Friedreich Ataxia
Interventions: Not listed
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Years to 18 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 3
States / cities: Los Angeles, California • Gainesville, Florida • Philadelphia, Pennsylvania

Conditions: Osteoarthritis
Interventions: Blood Draw; Procedure
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 30 Years to 65 Years · Male only
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cancer, Pregnancy Related, Gastro-Intestinal Disorder, Cardio-Respiratory Distress, Women's Health: Endometriosis, Autoimmune Diseases, Nephritis, Healthy, Neuro-Degenerative Disease
Interventions: Specimens obtained from surgical, phlebotomy or other non-invasive procedure; Procedure
Lead sponsor: iSpecimen Inc; Industry
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Lexington, Massachusetts

Conditions: Frontotemporal Dementia, Frontotemporal Degeneration, Alzheimer's Disease, Social Behavior
Interventions: Not listed
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 40 Years to 75 Years
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Peripheral Neuropathy, Neuro-Degenerative Disease, Neuromuscular Diseases
Interventions: Not listed
Lead sponsor: Elpida Therapeutics SPC; Industry
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2032
U.S. locations: 3
States / cities: San Francisco, California • Iowa City, Iowa • Dallas, Texas

Conditions: Neuro-Degenerative Disease, Cancer
Interventions: Clonidine Pill; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Friedreich Ataxia, Neuro-Degenerative Disease
Interventions: Not listed
Lead sponsor: Friedreich's Ataxia Research Alliance; Other
Eligibility: 4 Years to 80 Years
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2030
U.S. locations: 9
States / cities: Los Angeles, California • Denver, Colorado • Gainesville, Florida + 6 more

Conditions: Optic Nerve Disease, Macular Disease, Visual Pathway Disorder
Interventions: EyeCTester; Device
Lead sponsor: Neuro-Eye Diagnostic Systems, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Bellaire, Texas

Conditions: Alzheimer Disease
Interventions: [11C]-Pittsburgh Compound B ([11C]PiB), F 18 AV-1451 (Flortaucipir); Drug
Lead sponsor: Tammie L. S. Benzinger, MD, PhD; Other
Eligibility: 18 Years and older
Enrollment: 650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis, Huntington Disease, Lewy Body Dementia, Frontotemporal Dementia, Amyotrophic Lateral Sclerosis (ALS), APOE-4 Positive, Traumatic Brain Injury, Concussion, Post-Traumatic Stress Disorder, Down Syndrome, Neuro-Degenerative Disease, Normal Cognition
Interventions: Retinal and Choroidal Imaging; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Encephalopathy, Birth Defect, Intellectual Disability, Multiple Congenital Anomaly, Metabolic Disease, Epilepsy, Neuro-Degenerative Disease, Cerebral Palsy, Developmental Delay, Developmental Defect
Interventions: Whole Exome Sequencing; Diagnostic Test
Lead sponsor: University of California, San Francisco; Other
Eligibility: Up to 25 Years
Enrollment: 529 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 4
States / cities: Fresno, California • Oakland, California • San Francisco, California

Conditions: Cancer, Cardiac Disease, Pulmonary Disease, Neuro-Degenerative Disease, Renal Disease, Stroke, Sepsis, Hepatic Disease
Interventions: Active Intervention, Usual Care; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 55 Years and older
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 4
States / cities: Alexander City, Alabama • Meridian, Mississippi • Picayune, Mississippi + 1 more

Conditions: Neuro-Degenerative Disease
Interventions: Carbon 11 Butanol; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

100-Year Human Aging Study

Golf Instruction Versus Tai Chi for People With Parkinson's Disease

C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Progressive Multiple Sclerosis Refractory to Standard Therapy

Smell, Voice and Nasal Swabs as Markers for Neuro-degenerative Disorders

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Persons With Dementia and Their Extended Family Caregivers

Neurology Measures in FA Children

Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men

Distribution of Biospecimens From Biorepositories/Biobanks for Research Use

Study of Social Behavior and Emotion in Frontotemporal Dementia, Alzheimer's Disease and Controls

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies

FA Clinical Outcome Measures

Implementation of the NEDS EyeCTester App

Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)

Retinal Imaging in Neurodegenerative Disease

Clinical Utility of Pediatric Whole Exome Sequencing

A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

Carbon-11 Butanol: Whole Body Radiochemical and Radiation Safety