- Conditions
- Contact Lens Discomfort, Meibomian Gland Dysfunction
- Interventions
- BlephEx, Manual debridement
- Device
- Lead sponsor
- University of the Incarnate Word
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 35
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Dry Eye, Contact Lens Complication
- Interventions
- HydroEye®
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Contact Lens, Contact Lens Discomfort, Contact Lens Dryness
- Interventions
- Lifitegrast
- Drug
- Lead sponsor
- EV Clinical Trials
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Richardson, Texas
- Conditions
- Dry Eye Syndromes, Keratoconjunctivitis Sicca
- Interventions
- KPI-121, Placebo
- Drug
- Lead sponsor
- Kala Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 11
- States / cities
- Artesia, California • Mission Hills, California • Rancho Cordova, California + 8 more
- Conditions
- Dry Eye Disease (DED)
- Interventions
- DFL24498, Vehicle
- Drug · Other
- Lead sponsor
- Dompé Farmaceutici S.p.A
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 417 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 24
- States / cities
- Chandler, Arizona • Azusa, California • Glendale, California + 21 more
- Conditions
- Epiphora, Dacryostenosis, Dacryocystitis
- Interventions
- Proparacaine Hydrochloride ophthalmic solution, USP 0.5%, Balanced salt solution
- Drug
- Lead sponsor
- Louisiana State University Health Sciences Center in New Orleans
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 145 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Dry Eye Syndromes, Dry Eye, Ocular Inflammation, Ocular Surface Disease, Ocular Discomfort, Blepharitis
- Interventions
- Corneal Epithelial Stem Cell Transplant
- Other
- Lead sponsor
- Sloan W. Rush, MD
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Amarillo, Texas
- Conditions
- Eyes Dry Chronic
- Interventions
- ESBA105 ophthalmic solution, ESBA105 vehicle
- Biological · Other
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 334 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Ocular Discomfort
- Interventions
- Bausch & Lomb Multi-Purpose Solution, Ciba's Multi-Purpose Solution
- Device
- Lead sponsor
- Bausch & Lomb Incorporated
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 312 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Retina--Diseases, Retinal Detachment, Retinal Degeneration
- Interventions
- Schocket scleral depressor, Cotton tipped applicator
- Device
- Lead sponsor
- New York City Health and Hospitals Corporation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 87 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Blepharitis
- Interventions
- KPI-121, Vehicle
- Drug
- Lead sponsor
- Kala Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 206 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Artesia, California • Mission Hills, California + 5 more
- Conditions
- Contact Lens Discomfort, Dry Eye Disease, Meibomian Gland Dysfunction
- Interventions
- Bruder Moist Heat Compress, Washcloth
- Device · Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Contact Lens Discomfort, Dry Eye
- Interventions
- Systane Complete
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 3
- States / cities
- Birmingham, Alabama • Babylon, New York • Memphis, Tennessee
- Conditions
- Post Laser Vision Correction Pain and Discomfort
- Interventions
- Eye Shield
- Device
- Lead sponsor
- FORSIGHT Vision3
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 5
- States / cities
- San Diego, California • Chicago, Illinois • Boston, Massachusetts + 2 more
- Conditions
- Dry Eye
- Interventions
- Dextenza (IDI) (Sustained Release Dexamethasone), (0.4 mg), ProLong™ collagen plugs
- Drug · Other
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Pain
- Interventions
- proparacaine HCL 0.5%, proparacaine HCL 0.5% + 4% lidocaine solution, 3.5% viscous lidocaine gel
- Drug
- Lead sponsor
- Illinois Retina Associates
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Joliet, Illinois
- Conditions
- Contact Lens Complication
- Interventions
- Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A)
- Device
- Lead sponsor
- ORA, Inc.
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Glaucoma, Ocular Surface Disease
- Interventions
- Xiidra (Lifitegrast ophthalmic solution) 5%
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- Not listed
- Enrollment
- 75 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Fountain Valley, California
- Conditions
- Dry Eye, Meibomian Gland Dysfunction
- Interventions
- Varenicline 0.03Mg/Spray Nasal Soln
- Drug
- Lead sponsor
- University of California, Berkeley
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Berkeley, California
- Conditions
- Dry Eye Disease
- Interventions
- Difluprednate 0.05% ophthalmic emulsion, Difluprednate vehicle
- Drug · Other
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 722 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Pain
- Interventions
- 4% lidocaine, 3.5% ophthalmic lidocaine gel
- Drug
- Lead sponsor
- Miami VA Healthcare System
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Ocular Surface Disease
- Interventions
- Zocular Eyelid System Treatment
- Other
- Lead sponsor
- University of the Incarnate Word
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Dry Eye, Contact Lens Complication
- Interventions
- Orthokeratology
- Device
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Contact Lens Discomfort, Contact Lens-induced Corneal Disorder, Contact Lens Acute Red Eye, Contact Lens-induced Corneal Fluorescein Staining
- Interventions
- CLM2 topical gel, Placebo topical gel
- Drug
- Lead sponsor
- Glia, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Berkeley, California