Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease
Public ClinicalTrials.gov record NCT02813265. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Masked, Randomized, Controlled Study of KPI-121 0.25% Ophthalmic Suspension Compared to Vehicle in Subjects With Dry Eye Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to determine the efficacy and safety of KPI-121 0.25% ophthalmic suspension compared to vehicle (placebo) in subjects who have a documented clinical diagnosis of dry eye disease. The product will be studied over 14 days, with 1-2 drops instilled in each eye four times daily (QID).
Study identification
- NCT ID
- NCT02813265
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 918 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2016 (Actual)
- Primary completion
- Oct 2017 (Actual)
- Completion
- Oct 2017 (Actual)
- Last update posted
- Feb 3, 2021
2016 – 2017
United States locations
- U.S. sites
- 60
- U.S. states
- 26
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cornea and Cataract Consultants of Arizona | Phoenix | Arizona | 85032 | — |
| Schwartz Laser Eye Center | Scottsdale | Arizona | 85260 | — |
| Eyecare Arkansas, P.A. | Little Rock | Arkansas | 72205 | — |
| Little Rock Eye Clinic, LLP | Little Rock | Arkansas | 72205 | — |
| Sall Research Medical Center | Artesia | California | 90701 | — |
| Orange County Ophthalmology Medical Group | Garden Grove | California | 92843 | — |
| United Medical Research Institute | Inglewood | California | 90301 | — |
| North Valley Eye Medical Group | Mission Hills | California | 91345 | — |
| Montebello Medical Center, Inc. | Montebello | California | 90640 | — |
| LoBue Laser and Eye Medical Center | Murrieta | California | 92562 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| Pendleton Eye Center | Oceanside | California | 92056 | — |
| North Bay Eye Associates, Inc. | Petaluma | California | 94954 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Sacramento Eye Consultants | Sacramento | California | 95815 | — |
| Eye Center of Northern Colorado, PC | Fort Collins | Colorado | 80525 | — |
| Corneal Consultants of Colorado | Littleton | Colorado | 80209 | — |
| The Eye Center of Southern CT, P.C. | Hamden | Connecticut | 06518 | — |
| Florida Eye Microsurgical Institute, Inc. | Boynton Beach | Florida | 33426 | — |
| Eye Associates of Fort Myers | Fort Myers | Florida | 33901 | — |
| Shettle Eye Research, Inc. | Largo | Florida | 33773 | — |
| Atlantic Eye Center | Palm Coast | Florida | 32137 | — |
| The Eye Center of North Florida | Panama City | Florida | 32405 | — |
| Dixon Eye Care | Albany | Georgia | 31701 | — |
| Jacksoneye, S. C. | Lake Villa | Illinois | 60046 | — |
| Midwest Cornea Associates, LLC | Indianapolis | Indiana | 46290 | — |
| Stiles EyeCare Excellence and Glaucoma Institute | Overland Park | Kansas | 66213 | — |
| Clinical Eye Research of Boston | Winchester | Massachusetts | 01890 | — |
| Chu Vision Institute | Bloomington | Minnesota | 55420 | — |
| Lifelong Vision Foundation at Pepose Vision Institute | Chesterfield | Missouri | 63017 | — |
| Ophthalmology Associates | St Louis | Missouri | 63131 | — |
| Ophthalmology Consultants, Ltd. | St Louis | Missouri | 63131 | — |
| Wellish Vision Institute | Las Vegas | Nevada | 89119 | — |
| Matossian Eye Associates | Pennington | New Jersey | 08534 | — |
| Rochester Ophthalmological Group, PC | Rochester | New York | 14618 | — |
| Cornea Consultants of Albany | Slingerlands | New York | 12159 | — |
| South Shore Eye Center, LLP | Wantagh | New York | 11793 | — |
| Mundorf Eye Center | Charlotte | North Carolina | 28204 | — |
| Firozvi Research, LLC / North Carolina Eye, Ear, Nose & Throat | Durham | North Carolina | 27704 | — |
| Eyecare Center | Raleigh | North Carolina | 27603 | — |
| Bergstrom Eye Research | Fargo | North Dakota | 58103 | — |
| Abrams Eye Center | Cleveland | Ohio | 44115 | — |
| Opthalamic Surgeons & Consultants of Ohio | Columbus | Ohio | 43215 | — |
| Apex Eye | Mason | Ohio | 45040 | — |
| Roseburg Research Associates, LLC | Roseburg | Oregon | 97471 | — |
| Scott & Christie and Associates, PC | Cranberry Township | Pennsylvania | 16066 | — |
| Conestoga Eye | Lancaster | Pennsylvania | 17601 | — |
| UPMC Eye Center | Pittsburgh | Pennsylvania | 15213 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Total Eye Care, PA | Memphis | Tennessee | 38119 | — |
| Hill Country Eye Center | Cedar Park | Texas | 78613 | — |
| Houston Eye Associates | Houston | Texas | 77025 | — |
| The Eye Clinic of Texas, Affiliate of Houston Eye Associates | League City | Texas | 77573 | — |
| Lake Travis Eye and Laser Center | Leander | Texas | 78641 | — |
| Eye Clinics of South Texas | San Antonio | Texas | 78209 | — |
| R and R Eye Research, LLC | San Antonio | Texas | 78229 | — |
| Keystone Research - Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Tanner Clinic | Layton | Utah | 84041 | — |
| See Clearly Vision | McLean | Virginia | 22102 | — |
| Virginia Eye Consultants | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02813265, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2021 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02813265 live on ClinicalTrials.gov.