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ClinicalTrials.gov public records Last synced Sep 9, 2026, 11:38 PM EDT

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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pediatric Sedation Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients

NCT01170247
View directory record Official record
Conditions
Sedation
Interventions
Ketamine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
2 Years to 17 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 4 Interventional Results available

Dexmedetomidine and Propofol for Pediatric MRI Sedation

NCT03513757
View directory record Official record
Conditions
Headache, Tumor, Seizure Disorder, Neurofibromatoses, Hydrocephalus, Abdominal Neoplasm, Spine Deformity
Interventions
propofol, Dexmedetomidine, Glycopyrrolate, Lidocaine 1% Injectable Solution, Nitrous Oxide, Sevoflurane
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
12 Months to 60 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Feasibility of VR for Pediatric Renal Biopsies

NCT05267704
View directory record Official record
Conditions
Pain, Procedural, Procedural Anxiety, Sedation Complication
Interventions
Oculus Go Virtual Reality Headset
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational

Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures

NCT03220880
View directory record Official record
Conditions
Dexmedetomidine, Sedation
Interventions
Intranasal dexmedetomidine
Drug
Lead sponsor
Columbia University
Other
Eligibility
2 Months to 17 Years
Enrollment
578 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
8
States / cities
San Jose, California • Atlanta, Georgia • Springfield, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Results available

Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit

NCT01848158
View directory record Official record
Conditions
Agitation
Interventions
acupuncture, sham acupuncture
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Months to 17 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational

Pharmacologic Impact on Sedation Assessments

NCT01105663
View directory record Official record
Conditions
Pediatric Acute Lung Injury
Interventions
Pharmacokinetic Sampling and pharmacogenetic analysis
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Sep 9, 2026, 11:38 PM EDT
Recruiting Phase 2 Interventional

Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea

NCT05303987
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Propofol sedation, Dexmedetomidine sedation
Drug
Lead sponsor
Erin Kirkham
Other
Eligibility
3 Years to 11 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 2 Interventional Results available

Pediatric Radiation Oncology With Movie Induced Sedation Effect (PROMISE)

NCT05148078
View directory record Official record
Conditions
Pediatric Cancer
Interventions
PROMISE (Pediatric Radiation Oncology with Movie Induced Sedation Effect)
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
3 Years to 11 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational

Sound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, Delirium Scores and Patient Heart Rate

NCT04777695
View directory record Official record
Conditions
Noise Exposure, Sedative Withdrawal Delirium, Sedative Toxicity
Interventions
Decibel Monitor
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
Up to 22 Years
Enrollment
64 participants
Timeline
2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

NCT03980067
View directory record Official record
Conditions
Behavior, Child, Anxiety
Interventions
Virtual Reality Game
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
6 Years to 17 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 9, 2026, 11:38 PM EDT
Terminated Phase 3 Interventional Results available

Comparing Safety and Efficacy of Dexmedetomidine and Propofol

NCT01152021
View directory record Official record
Conditions
Safety and Efficacy of Sedation Medications
Interventions
Dexmedetomidine, Propofol
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 11 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Terminated Not applicable Interventional Results available

Cycling of Sedative Infusions in Critically Ill Pediatric Patients

NCT01333059
View directory record Official record
Conditions
Respiratory Failure
Interventions
Midazolam, Normal saline, Fentanyl
Drug
Lead sponsor
Javier Gelvez, MD
Other
Eligibility
Up to 18 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 4 Interventional Results available

The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric Endoscopy

NCT02952222
View directory record Official record
Conditions
Anesthesia
Interventions
Dexmedetomidine, Propofol (Group P), Propofol (Group DP)
Drug
Lead sponsor
Keira Mason
Other
Eligibility
7 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Sep 9, 2026, 11:38 PM EDT
Terminated Early Phase 1 Interventional

Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study

NCT03067974
View directory record Official record
Conditions
Failed Moderate Sedation During Procedure, Ketamine Adverse Reaction
Interventions
Ketamine Hcl 100Mg/Ml Inj
Drug
Lead sponsor
University of Arizona
Other
Eligibility
2 Years to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 27, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Recruiting Phase 3 Interventional

Optimizing Pain Treatment in Children On Mechanical Ventilation

NCT06994442
View directory record Official record
Conditions
Mechanical Ventilation, Pediatric Acute Respiratory Failure, Analgesics, Opioid, Sedation and Analgesia
Interventions
Acetaminophen, Ketorolac, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
2 Months to 17 Years
Enrollment
644 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
16
States / cities
Little Rock, Arkansas • Washington D.C., District of Columbia • Ann Arbor, Michigan + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

Use of a Multimedia Presentation for Informed Consent

NCT01955070
View directory record Official record
Conditions
Improving Informed Consent Process
Interventions
Multimedia Presentation for Ketamine sedation
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
1 Year to 18 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2013 · Synced Sep 9, 2026, 11:38 PM EDT
Terminated Phase 4 Interventional Results available

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

NCT03781817
View directory record Official record
Conditions
Trauma, Fractures, Closed, Children, Only, Deep Sedation, Ketamine
Interventions
Intravenous Ketamine, Intranasal Ketamine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Year to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies

NCT00515359
View directory record Official record
Conditions
Encephalopathy, Developmental Delay and Behavioral Changes, Cord Tumor Compression or Instability, Cord Tethering or Malformation
Interventions
Intermittent Propofol Sedation, Continuous Propofol Sedation
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
1 Month to 18 Years
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 2 Interventional Results available

Phase II Pharmacokinetic and Pharmacodynamic Study of DEX in Subjects Aged 12 Months Through <24 Months

NCT01378988
View directory record Official record
Conditions
Sedation, Pain
Interventions
Dexmedetomidine
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
12 Months to 23 Months
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational

Study to Evaluate Causes of Failure to Extubate

NCT01598246
View directory record Official record
Conditions
Extubation Failures
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
Up to 18 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

Post Anesthesia Care Unit (PACU) Weighted Blanket Study

NCT05632640
View directory record Official record
Conditions
Cardiac Catheterization, Electrophysiology Procedure, Pediatric Cardiology
Interventions
Standard of Care, Weighted blanket
Other · Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 1 Interventional

Pharmacokinetic Study of Dexmedetomidine After Intra-Nasal and Buccal Dosing in Children

NCT03668951
View directory record Official record
Conditions
Heart Diseases
Interventions
Dexmedetomidine buccal, Dexmedetomidine Intranasal
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Months to 48 Months
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 2 Interventional Results available

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

NCT01516684
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
placebo administration, EMLA, propofol, fentanyl citrate
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 22 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 9, 2026, 11:38 PM EDT