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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers

Oral Gut Liver Axis in Cirrhosis

NCT03030820
Conditions
Cirrhosis, Periodontitis, Gingivitis
Interventions
Dental Cleaning
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Palmoplantar Pustulosis
Interventions
Bimekizumab, Placebo
Drug
Lead sponsor
UCB Biopharma SRL
Industry
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
6
States / cities
Birmingham, Alabama • Coral Gables, Florida • Auburn Hills, Michigan + 3 more
Conditions
Periodontal Disease, Periodontal Surgery
Interventions
Blood samples for inflammatory markers, periodontal surgery, Periodontal maintenance, Non-surgical deep cleaning
Other · Procedure
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bone Regenerative Techniques in Endodontic Microsurgery

NCT04514991
Conditions
Apical Periodontitis
Interventions
Foundation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers Results available

Periodontal Disease Prevention Study

NCT01584479
Conditions
Periodontitis
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
34 Years to 55 Years
Enrollment
5,117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Chronic Periodontitis, End Stage Renal Disease
Interventions
Test
Other
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Periodontitis, Calculus, Dental, Bone Loss, Alveolar
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Emdogain Minimally Invasive Surgical Technique

NCT02551770
Conditions
Periodontitis
Interventions
Scaling and root planing, Scaling and root planing without Emdogain, Emdogain application
Procedure · Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
21 Years to 85 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Cullman, Alabama • Aurora, Colorado
Conditions
Periodontal Disease
Interventions
Investigational Procedure
Procedure
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
30 Years to 70 Years
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Iowa City, Iowa • Somerville, Massachusetts • Stony Brook, New York + 1 more
Conditions
Periodontitis, Chronic Kidney Disease
Interventions
Scaling root planing, Supragingival Prophylaxis
Procedure
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Farmington, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

NCT07053969
Conditions
Dental Implantation, Missing Teeth, Periodontitis, Adult, Mucositis
Interventions
Enamel Matrix Derivative
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 18 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Acute Myeloid Leukemia
Interventions
Planned Chemotherapy
Other
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Adjunctive Hydrogen Peroxide for Periodontal Therapy

NCT03262701
Conditions
Periodontitis, Chronic
Interventions
Hydrogen Peroxide Gel, 13 weeks, Hydrogen Peroxide Gel, 26 weeks, Scaling and Root planing group
Drug · Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Loma Linda, California
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms and Treatment Response of Aggressive Periodontitis in Children

NCT01330719
Conditions
Aggressive Periodontitis
Interventions
Diseased periodontal treatment, Conventional periodontal treatment
Procedure
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 90 Years
Enrollment
514 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2022
U.S. locations
10
States / cities
Brooker, Florida • Fort Lauderdale, Florida • Gainesville, Florida + 6 more
Recruiting No phase listed Observational Accepts healthy volunteers

Association of Periodontal Inflammation on Immune Response in Wound Healing

NCT04805320
Conditions
Inflammation of Mouth
Interventions
Dental Extraction
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
21 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Periodontitis
Interventions
B-TCP + 0.3 mg/ml rhPDGF-BB in buffer, B-TCP + 1.0 mg/ml rhPDGF-BB in buffer, B-TCP +buffer
Biological
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Periodontitis, Diabetes Mellitus Type 2
Interventions
local antibiotic application of topical minocycline, Scaling and Root Planing
Drug · Procedure
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Effect of Actonel on Periodontal Health of Postmenopausal Women

NCT00594334
Conditions
Periodontal Disease
Interventions
Risedronate
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
40 Years to 80 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Optical Sensor for Photodynamic Detection of Oral Pathology

NCT00540774
Conditions
Mouth Diseases
Interventions
detection of oral pathology
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
1,004 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2026
U.S. locations
1
States / cities
Irvine, California
Conditions
Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation, Periodontal Attachment Loss, Periodontal Bone Loss, Surgery
Interventions
Not listed
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment

NCT06110494
Conditions
Apical Periodontitis, Pulp Disease, Dental
Interventions
Iron oxide nanoparticles treatment Ferumoxytol/H2O2, NaOCl, NaCl, supplementary irrigation
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Periodontitis
Interventions
Minocycline HCL Microspheres
Drug
Lead sponsor
OraPharma
Industry
Eligibility
30 Years to 65 Years
Enrollment
128 participants
Timeline
Started 2004
U.S. locations
5
States / cities
Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 2 more
Conditions
Type II Diabetes, Periodontal Disease
Interventions
Triclosan containing toothpaste, Non-triclosan containing toothpaste
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Completed Phase 3 Interventional Results available

Antibiotic Study for Dental Implants

NCT00662532
Conditions
Periodontitis
Interventions
Minocycline HCl
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
4
States / cities
Aurora, Colorado • Ann Arbor, Michigan • Hazlet, New Jersey + 1 more