Mechanisms and Treatment Response of Aggressive Periodontitis in Children
Public ClinicalTrials.gov record NCT01330719. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Mechanisms and Treatment Response of Aggressive Periodontitis in Children: Aberrant Immunological Phenotypes/Functions in the Progression of AgP
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Although of low prevalence, aggressive periodontitis is a rapid destructive form of periodontal disease that initiates at a young age, leading to premature loss of first molars and incisors. Little is known on the mechanisms of this disease. It is imperative to understand mechanisms of disease to establish proper treatment. We have established a controlled study in a comparable population presenting similar aggressive disease characteristics to evaluate the mechanisms of this disease. It is the goal of this study to determine immunological and microbiological mechanisms responsible for the rapid tissue destruction in children with localized aggressive periodontitis and how traditional periodontal intervention affects these mechanisms. Important knowledge gained with this proposal will aid in defining specific treatment approaches to better control disease progression and prevent disease initiation in susceptible individuals.
Study identification
- NCT ID
- NCT01330719
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 514 participants
Conditions and interventions
Conditions
Interventions
- Diseased periodontal treatment Procedure
- Conventional periodontal treatment Procedure
Procedure
Eligibility (public fields only)
- Age range
- 5 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2006 (Actual)
- Primary completion
- May 29, 2019 (Actual)
- Completion
- Dec 2, 2022 (Actual)
- Last update posted
- Mar 12, 2024
2006 – 2022
United States locations
- U.S. sites
- 10
- U.S. states
- 2
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Acorn Dental Clinic | Brooker | Florida | 32622 | — |
| Broward College | Fort Lauderdale | Florida | 33301 | — |
| Dental Clinical Research Unit, University of Florida | Gainesville | Florida | 32610 | — |
| Azalea Dental Clinic | Gainesville | Florida | 32640 | — |
| UF Hialeah Dental Clinic | Hialeah | Florida | 33013 | — |
| Duval County Department of Health | Jacksonville | Florida | 32206 | — |
| UF Naples Pediatric Dental Clinic | Naples | Florida | 34113 | — |
| Gadsden County Health Department--Quincy Dental Clinic | Quincy | Florida | 32353 | — |
| Leon County Health Department | Tallahassee | Florida | 32310 | — |
| University of Kentucky | Lexington | Kentucky | 40506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01330719, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 12, 2024 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01330719 live on ClinicalTrials.gov.