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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Persian Gulf War Syndrome Clear all
Completed Phase 2 Interventional Results available

Gulf War Illness Nasal Irrigation Study

NCT01700725
View directory record Official record
Conditions
Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
Interventions
Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
35 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Phase 3 Interventional

Coenzyme Q10 for Gulf War Illness: A Replication Study

NCT06515184
View directory record Official record
Conditions
Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorder, Respiratory Chain
Interventions
PharmaNord Bio-Quinone Active CoQ10 Gold 100mg, PharmaNord Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Terminated Early Phase 1 Interventional

Ketamine in Veterans With Gulf War Illness

NCT04712071
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Ketamine Hydrochloride
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Jul 21, 2026, 9:24 PM EDT
Not listed Phase 1 Interventional

Understanding GWI: Integrative Modeling

NCT04255498
View directory record Official record
Conditions
Gulf War Illness, Persian Gulf Syndrome, Occupational Diseases
Interventions
Etanercept, Mifepristone
Drug
Lead sponsor
South Florida Veterans Affairs Foundation for Research and Education
Federal
Eligibility
40 Years to 70 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 2 Interventional

Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms

NCT01543997
View directory record Official record
Conditions
Sleep Disturbance, Persian Gulf War Syndrome in Veteran
Interventions
Mind-Body Bridging Program, Supportive Education
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
38 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Not applicable Interventional

Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome

NCT07151248
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Cranial electrical/electrotherapy stimulation (CES), Sham Cranial electrical/electrotherapy stimulation (CES)
Device
Lead sponsor
Emory University
Other
Eligibility
40 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Phase 3 Interventional

Confirmation of Diet as a Treatment for Gulf War Illness

NCT05675878
View directory record Official record
Conditions
Gulf War Syndrome, Gulf War Illness
Interventions
Dietary Intervention
Behavioral
Lead sponsor
American University
Other
Eligibility
50 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Fort Lauderdale, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Phase 2 Interventional

Resistant Potato Starch to Alleviate GWI

NCT05820893
View directory record Official record
Conditions
Gulf War Illness
Interventions
Resistant Potato Starch
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Follow-up of Psychological and Neurocognitive Gulf War Outcome: Relation to Stress

NCT00018707
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2003
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Not applicable Interventional

Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness

NCT06716411
View directory record Official record
Conditions
Persian Gulf Syndrome, Gulf War Syndrome, Multiple Chronic Illnesses, Occupational Diseases, War-Related Injuries, Wounds and Injuries
Interventions
Acupuncture
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
10
States / cities
Berkeley, California • Los Angeles, California • Colorado Springs, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Early Phase 1 Interventional

GWICTIC: NAC Mechanistic Study in Gulf War Veterans

NCT04987775
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
N-Acetyl Cysteine, Placebo
Drug
Lead sponsor
Nova Southeastern University
Other
Eligibility
47 Years to 70 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Palo Alto, California • Fort Lauderdale, Florida • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome

NCT00100425
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Viceral Perception Testing
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 72 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2000
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alleviating Headache and Pain in GWI With Neuronavigation Guided rTMS

NCT03030794
View directory record Official record
Conditions
Gulf War Syndrome, Headache
Interventions
Repetitive transcranial magnetic stimulation, Repetitive transcranial magnetic stimulation (sham)
Device
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Phase 2 Interventional

Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT)

NCT05355272
View directory record Official record
Conditions
Gulf War Syndrome, Adult Growth Hormone Deficiency
Interventions
Recombinant human growth hormone
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Houston, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans

NCT00810225
View directory record Official record
Conditions
Gulf War Illness, Persian Gulf War Syndrome
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
Not listed
Enrollment
516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment

NCT00252629
View directory record Official record
Conditions
Apnea, Sleep, Chronic Fatigue Syndrome
Interventions
Nasal CPAP treatment during sleep
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
32 Years to 52 Years · Male only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational

Mechanisms of Mitochondrial Defects in Gulf War Syndrome

NCT01264471
View directory record Official record
Conditions
Gulf War Syndrome, Mitochondrial Disease
Interventions
Skin biopsy, Blood Collection
Procedure
Lead sponsor
Medical Neurogenetics, LLC
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2015 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Gulf War Digestive Health Study

NCT00680836
View directory record Official record
Conditions
Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
Interventions
Placebo, Rifaximin
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
35 Years to 72 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 3 Interventional

Exercise and Behavioral Therapy Trial (EBT).

NCT00007748
View directory record Official record
Conditions
Persian Gulf Syndrome
Interventions
Aerobic exercise, Cognitive behavioral therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
1,064 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
28
States / cities
Birmingham, Alabama • San Diego, California • San Francisco, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2015 · Synced Jul 21, 2026, 9:24 PM EDT
Not listed Phase 2 Interventional

Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER)

NCT03665740
View directory record Official record
Conditions
Gulf War Illness
Interventions
Resveratrol
Drug
Lead sponsor
VISN 17 Center of Excellence
Federal
Eligibility
44 Years to 68 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Mindfulness-Based Stress Reduction for Gulf War Syndrome

NCT01267045
View directory record Official record
Conditions
Persian Gulf Syndrome
Interventions
Mindfulness-based stress reduction
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 6, 2015 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Effects of Botanical Microglia Modulators in Gulf War Illness

NCT02909686
View directory record Official record
Conditions
Gulf War Illness
Interventions
Boswellia Serrata, Curcumin, Epimedium, Fisetin, Luteolin, Nettle, Pycnogenol, Reishi Mushroom, Resveratrol, Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
39 Years to 65 Years · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Antibiotic Treatment of Gulf War Veterans' Illnesses

NCT00007735
View directory record Official record
Conditions
Persian Gulf Syndrome, Mycoplasma Infections
Interventions
Doxycycline (200mg/day) or Placebo
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2001
U.S. locations
26
States / cities
Birmingham, Alabama • San Diego, California • Washington D.C., District of Columbia + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Assessing Neuroinflammation in GWI Using MRS

NCT04638998
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Magnetic Resonance Spectroscopic Imaging, Blood draw
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
46 Years to 70 Years · Male only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Jul 21, 2026, 9:24 PM EDT