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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:42 PM EDT

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Showing 1–24 of 151 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Prostate Biopsy Clear all
Not listed Not applicable Interventional

MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer

NCT04599218
View directory record Official record
Conditions
Prostate Disease, Elevated Prostate Specific Antigen, Family History of Prostate Cancer, Positive Digital Rectal Exam, Prostate Cancer
Interventions
Prostate Biopsy, MR US Fusion Guided Prostate Biopsy, MR/TRUS Fusion Guided Prostate Biopsy
Other · Device
Lead sponsor
Ardeshir Rastinehad
Other
Eligibility
18 Years and older · Male only
Enrollment
1,586 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
Lake Success, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Phase 4 Interventional

Local Anesthesia for Prostate Biopsy

NCT00422708
View directory record Official record
Conditions
Prostate Cancer
Interventions
Local anesthesia
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years · Male only
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2010 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rapid PCR to Guide Antibiotic Therapy at the Time of Prostate Biopsy

NCT03040050
View directory record Official record
Conditions
Antibiotic Therapy, Prostate Biopsy
Interventions
rPCR results, Control group
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
50 Years and older · Male only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

MRI Based Active Selection for Treatment Trial

NCT02242773
View directory record Official record
Conditions
Prostate Cancer
Interventions
Multi-Parametric MRI, MRI-Guided Biopsy
Device
Lead sponsor
University of Miami
Other
Eligibility
35 Years to 85 Years · Male only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational

MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research

NCT02313623
View directory record Official record
Conditions
Prostate Cancer
Interventions
Prostate Fusion Biopsy
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain

NCT05803096
View directory record Official record
Conditions
Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer, Prostate Adenocarcinoma, Anxiety and Fear, Pain
Interventions
Self-Administered Nitrous Oxide, Oxygen
Drug · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 85 Years · Male only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Phase 2 Interventional Results available

68Ga PSMA 11 PET/MRI and 68Ga RM2 PET/MRI for Biopsy Guidance in Patients With Suspected Prostate Cancer

NCT03809078
View directory record Official record
Conditions
Prostate Cancer
Interventions
68Ga RM2, 68Ga-PSMA-11, Investigational PET scanner coils and software
Drug · Device
Lead sponsor
Andrei Iagaru
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated No phase listed Observational

MRI Before Biopsy in Diagnosing Patients With Prostate Cancer

NCT02131207
View directory record Official record
Conditions
Prostate Cancer
Interventions
magnetic resonance imaging, prostate biopsy
Device · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
40 Years to 75 Years · Male only
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2017 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Phase 3 Interventional Results available

"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk

NCT00056407
View directory record Official record
Conditions
Neoplasms, Prostate
Interventions
Dutasteride, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
50 Years to 75 Years · Male only
Enrollment
8,231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
297
States / cities
Birmingham, Alabama • Homewood, Alabama • Huntsville, Alabama + 236 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2016 · Synced Oct 21, 2026, 10:42 PM EDT
Recruiting Phase 3 Interventional

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

NCT03769766
View directory record Official record
Conditions
Prostate Cancer
Interventions
Curcumin, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
40 Years to 89 Years · Male only
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

NCT02643303
View directory record Official record
Conditions
Head and Neck Squamous Cell Carcinoma, Breast Cancer, Sarcoma, Merkel Cell Carcinoma, Cutaneous T-Cell Lymphoma, Melanoma, Renal Cancer, Bladder Cancer, Prostate Cancer, Testicular Cancer, Solid Tumor
Interventions
Durvalumab, Tremelimumab, Poly-ICLC
Drug
Lead sponsor
Ludwig Institute for Cancer Research
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
7
States / cities
Atlanta, Georgia • Lebanon, New Hampshire • Buffalo, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated Not applicable Interventional Results available

ARFI Imaging for Targeted Prostate Biopsy

NCT04607135
View directory record Official record
Conditions
Prostate Cancer
Interventions
Acoustic radiation force impulse (ARFI), Ultrasound
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 21, 2026, 10:42 PM EDT
Withdrawn Phase 2 Interventional

Ciprofloxacin Compared to Placebo in Diagnosing Prostate Cancer in Patients Undergoing Prostate Biopsy

NCT02252978
View directory record Official record
Conditions
Prostate Cancer
Interventions
ciprofloxacin, placebo, quality-of-life assessment, laboratory biomarker analysis
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Salisbury, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 21, 2026, 10:42 PM EDT
Not listed Not applicable Interventional

MR/TRUS Fusion Guided Prostate Biopsy

NCT04026763
View directory record Official record
Conditions
Prostate Disease, Elevated Prostate Specific Antigen, Family History of Prostate Cancer, Positive Digital Rectal Exam
Interventions
prostate biopsy, MR US Fusion Guided Prostate Biopsy, MR/TRUS Fusion Guided Prostate Biopsy
Procedure · Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Male only
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2019 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Phase 2 Interventional Results available

PSMA-PET for Biopsy and Treatment Guidance in Primary Prostate Cancer

NCT03429244
View directory record Official record
Conditions
Prostate Cancer
Interventions
68Ga-PSMA-11 PET-MRI
Diagnostic Test
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Study On Lidocaine Vs. Placebo Pain Control During Transrectal Ultrasound Guided Prostate Biopsy

NCT00441532
View directory record Official record
Conditions
Prostate Cancer
Interventions
Lidocaine
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 23, 2011 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated Phase 2 Interventional Results available

Neoadjuvant Chemohormonal Therapy Followed by Salvage Surgery for High Risk PSA

NCT01531205
View directory record Official record
Conditions
Prostate Cancer
Interventions
Androgen Ablation, Cabazitaxel, Salvage Therapy, Neoadjuvant Treatment - Hormonal Therapy, Neoadjuvant Treatment - Cabazitaxel
Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated No phase listed Observational

Registry to Measure the Impact of Adding Genomic Testing

NCT02454595
View directory record Official record
Conditions
Prostate Cancer
Interventions
Registry
Behavioral
Lead sponsor
Myriad Genetic Laboratories, Inc.
Industry
Eligibility
55 Years and older · Male only
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated Not applicable Interventional

Guided Biopsy for Mapping Prostate Cancer

NCT01007214
View directory record Official record
Conditions
Prostate Cancer
Interventions
Prostatectomy
Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Oct 21, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional

Evaluation of the Performance of a Novel Prostate Biopsy System Compared With Standard of Care Biopsy Needle on Quantitative and Qualitative Tissue Parameters

NCT05470127
View directory record Official record
Conditions
Prostate Disease, Prostate CA
Interventions
Prostate biopsy needle
Device
Lead sponsor
Uro-1 Medical
Industry
Eligibility
18 Years to 90 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cartersville, Georgia
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational

Validation of Digital Morphometry for Cancer Risk in Benign Prostate Biopsies

NCT01594502
View directory record Official record
Conditions
Prostate Cancer
Interventions
Dutasteride, Placebo
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 75 Years · Male only
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 12, 2020 · Synced Oct 21, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional

MRI Guided Prostate Biopsy

NCT06302595
View directory record Official record
Conditions
Suspected Prostate Cancer
Interventions
MRI-guided prostate biopsy using the needle holder frame.
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
30 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated Not applicable Interventional

MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk Prostate Ca

NCT02564549
View directory record Official record
Conditions
Prostate Cancer, Prostate Adenocarcinoma, Multiparametric MRI, Gleason's Score 6
Interventions
TRUS-guided biopsy, mpMRI with targeted biopsy
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
40 Years and older · Male only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 21, 2026, 10:42 PM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

PSMA PET Combined With MRI for the Detection of PCa

NCT07052214
View directory record Official record
Conditions
PCA, Prostate Cancer, Prostatic Neoplasm, PSMA PET, Diagnostic Imaging, Elevated PSA, Positron Emission Tomography, Prostate Biopsy, Carcinoma of the Prostate
Interventions
68Ga-PSMA-11
Drug
Lead sponsor
Telix Pharmaceuticals (Innovations) Pty Limited
Industry
Eligibility
18 Years and older · Male only
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
16
States / cities
Los Angeles, California • San Francisco, California • Boca Raton, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 10:42 PM EDT