ClinicalTrials.gov record
"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk
ClinicalTrials.gov ID: NCT00056407
Public ClinicalTrials.gov record NCT00056407. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy and Safety of Dutasteride 0.5 mg Administered Orally Once Daily for Four Years to Reduce the Risk of Biopsy-Detectable Prostate Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are defined by the study entrance criteria as being at an increased risk for prostate cancer. Study visits to the clinic will occur every 6 months for up to 4 years (10 clinic visits), and a prostate biopsy will be performed at 2 and 4 years of treatment.
Study identification
- NCT ID
- NCT00056407
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,231 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 75 Years
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2003
- Primary completion
- Dec 31, 2008
- Completion
- Mar 31, 2009
- Last update posted
- Sep 22, 2016
2003 – 2009
United States locations
- U.S. sites
- 297
- U.S. states
- 46
- U.S. cities
- 239
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Birmingham | Alabama | 35209 | — |
| GSK Investigational Site | Homewood | Alabama | 35209 | — |
| GSK Investigational Site | Huntsville | Alabama | 35801 | — |
| GSK Investigational Site | Mobile | Alabama | 36608 | — |
| GSK Investigational Site | Anchorage | Alaska | 99508 | — |
| GSK Investigational Site | Phoenix | Arizona | 85014 | — |
| GSK Investigational Site | Phoenix | Arizona | 85023 | — |
| GSK Investigational Site | Phoenix | Arizona | 85032 | — |
| GSK Investigational Site | Scottsdale | Arizona | 85258 | — |
| GSK Investigational Site | Sun City | Arizona | 85375 | — |
| GSK Investigational Site | Tucson | Arizona | 85710 | — |
| GSK Investigational Site | Tucson | Arizona | 85712 | — |
| GSK Investigational Site | Little Rock | Arkansas | 72205 | — |
| GSK Investigational Site | Little Rock | Arkansas | 72211 | — |
| GSK Investigational Site | Anaheim | California | 92801 | — |
| GSK Investigational Site | Atherton | California | 94027 | — |
| GSK Investigational Site | Culver City | California | 90232 | — |
| GSK Investigational Site | Encino | California | 91316 | — |
| GSK Investigational Site | Fountain Valley | California | 92708 | — |
| GSK Investigational Site | Fresno | California | 93720 | — |
| GSK Investigational Site | Irvine | California | 92618 | — |
| GSK Investigational Site | La Mesa | California | 91942 | — |
| GSK Investigational Site | Laguna Hills | California | 92653 | — |
| GSK Investigational Site | Long Beach | California | 90806 | — |
| GSK Investigational Site | Los Angeles | California | 90024 | — |
| GSK Investigational Site | Los Angeles | California | 90033 | — |
| GSK Investigational Site | Los Angeles | California | 90048 | — |
| GSK Investigational Site | Los Angeles | California | 90059 | — |
| GSK Investigational Site | Los Angeles | California | 90073 | — |
| GSK Investigational Site | Mather | California | 95655 | — |
| GSK Investigational Site | Newport Beach | California | 92660 | — |
| GSK Investigational Site | Orange | California | 92869 | — |
| GSK Investigational Site | Pico Rivera | California | 90660 | — |
| GSK Investigational Site | Poway | California | 92064 | — |
| GSK Investigational Site | Sacramento | California | 95816 | — |
| GSK Investigational Site | Salinas | California | 93901 | — |
| GSK Investigational Site | San Bernardino | California | 92404 | — |
| GSK Investigational Site | San Diego | California | 92103-6204 | — |
| GSK Investigational Site | San Diego | California | 92103 | — |
| GSK Investigational Site | San Diego | California | 92120 | — |
| GSK Investigational Site | San Diego | California | 92128 | — |
| GSK Investigational Site | San Francisco | California | 94108 | — |
| GSK Investigational Site | San Francisco | California | 94121 | — |
| GSK Investigational Site | San Ramon | California | 94583 | — |
| GSK Investigational Site | Santa Monica | California | 90404 | — |
| GSK Investigational Site | Stanford | California | 94305 | — |
| GSK Investigational Site | Temecula | California | 92591 | — |
| GSK Investigational Site | Torrance | California | 90505 | — |
| GSK Investigational Site | Upland | California | 91786 | — |
| GSK Investigational Site | Van Nuys | California | 91405 | — |
| GSK Investigational Site | Walnut Creek | California | 94598 | — |
| GSK Investigational Site | Westchester | California | 90045 | — |
| GSK Investigational Site | Aurora | Colorado | 80010 | — |
| GSK Investigational Site | Aurora | Colorado | 80012 | — |
| GSK Investigational Site | Denver | Colorado | 80211 | — |
| GSK Investigational Site | Denver | Colorado | 80220 | — |
| GSK Investigational Site | Englewood | Colorado | 80113 | — |
| GSK Investigational Site | Longmont | Colorado | 80501 | — |
| GSK Investigational Site | Hartford | Connecticut | 06106 | — |
| GSK Investigational Site | Middlebury | Connecticut | 06762 | — |
| GSK Investigational Site | New Britain | Connecticut | 06052 | — |
| GSK Investigational Site | Trumbull | Connecticut | 06611 | — |
| GSK Investigational Site | Washington D.C. | District of Columbia | 20307-5001 | — |
| GSK Investigational Site | Aventura | Florida | 33180 | — |
| GSK Investigational Site | Clearwater | Florida | 33756 | — |
| GSK Investigational Site | Clearwater | Florida | 33761 | — |
| GSK Investigational Site | Delray Beach | Florida | 33484 | — |
| GSK Investigational Site | Fort Myers | Florida | 33916 | — |
| GSK Investigational Site | Jacksonville | Florida | 32216 | — |
| GSK Investigational Site | Jacksonville | Florida | 32224 | — |
| GSK Investigational Site | Jacksonville | Florida | 32257 | — |
| GSK Investigational Site | Lake Worth | Florida | 33461 | — |
| GSK Investigational Site | Largo | Florida | 33773 | — |
| GSK Investigational Site | Longwood | Florida | 32750 | — |
| GSK Investigational Site | Margate | Florida | 33063 | — |
| GSK Investigational Site | Melbourne | Florida | 32901 | — |
| GSK Investigational Site | Miami | Florida | 33156 | — |
| GSK Investigational Site | New Port Richey | Florida | 34652 | — |
| GSK Investigational Site | Ocala | Florida | 34471 | — |
| GSK Investigational Site | Ocala | Florida | 34474 | — |
| GSK Investigational Site | Okeechobee | Florida | 34972 | — |
| GSK Investigational Site | Orange Park | Florida | 32073 | — |
| GSK Investigational Site | Orlando | Florida | 32803 | — |
| GSK Investigational Site | Panama City | Florida | 32405 | — |
| GSK Investigational Site | Plantation | Florida | 33317 | — |
| GSK Investigational Site | Sarasota | Florida | 34237 | — |
| GSK Investigational Site | South Daytona | Florida | 32119 | — |
| GSK Investigational Site | St. Petersburg | Florida | 33703 | — |
| GSK Investigational Site | Stuart | Florida | 34996 | — |
| GSK Investigational Site | Tallahassee | Florida | 32308 | — |
| GSK Investigational Site | Tamarac | Florida | 33321 | — |
| GSK Investigational Site | West Palm Beach | Florida | 33409 | — |
| GSK Investigational Site | Atlanta | Georgia | 30308 | — |
| GSK Investigational Site | Atlanta | Georgia | 30309 | — |
| GSK Investigational Site | Atlanta | Georgia | 30342 | — |
| GSK Investigational Site | Augusta | Georgia | 30912 | — |
| GSK Investigational Site | Fayetteville | Georgia | 30214 | — |
| GSK Investigational Site | Marietta | Georgia | 30060 | — |
| GSK Investigational Site | Roswell | Georgia | 30076 | — |
| GSK Investigational Site | Woodstock | Georgia | 30189 | — |
| GSK Investigational Site | Honolulu | Hawaii | 96813 | — |
| GSK Investigational Site | Coeur d'Alene | Idaho | 83814 | — |
| GSK Investigational Site | Chicago | Illinois | 60612 | — |
| GSK Investigational Site | Chicago | Illinois | 60616 | — |
| GSK Investigational Site | Chicago | Illinois | 60637 | — |
| GSK Investigational Site | Chicago | Illinois | 60640 | — |
| GSK Investigational Site | Galesburg | Illinois | 61401 | — |
| GSK Investigational Site | Kankakee | Illinois | 60901 | — |
| GSK Investigational Site | Maywood | Illinois | 60153 | — |
| GSK Investigational Site | Melrose Park | Illinois | 60160 | — |
| GSK Investigational Site | Niles | Illinois | 60714 | — |
| GSK Investigational Site | Springfield | Illinois | 62781 | — |
| GSK Investigational Site | Evansville | Indiana | 47714 | — |
| GSK Investigational Site | Fort Wayne | Indiana | 46825 | — |
| GSK Investigational Site | Indianapolis | Indiana | 46202 | — |
| GSK Investigational Site | Jeffersonville | Indiana | 47130 | — |
| GSK Investigational Site | Kansas City | Kansas | 66160 | — |
| GSK Investigational Site | Overland Park | Kansas | 66211 | — |
| GSK Investigational Site | Wichita | Kansas | 67208 | — |
| GSK Investigational Site | Lexington | Kentucky | 40508 | — |
| GSK Investigational Site | Covington | Louisiana | 70433 | — |
| GSK Investigational Site | Gretna | Louisiana | 70056 | — |
| GSK Investigational Site | Houma | Louisiana | 70360 | — |
| GSK Investigational Site | Lafayette | Louisiana | 70503 | — |
| GSK Investigational Site | Metairie | Louisiana | 70001 | — |
| GSK Investigational Site | New Orleans | Louisiana | 70115 | — |
| GSK Investigational Site | New Orleans | Louisiana | 70119 | — |
| GSK Investigational Site | New Orleans | Louisiana | 70121 | — |
| GSK Investigational Site | Ruston | Louisiana | 71270 | — |
| GSK Investigational Site | Shreveport | Louisiana | 71106 | — |
| GSK Investigational Site | Annapolis | Maryland | 21401 | — |
| GSK Investigational Site | Baltimore | Maryland | 21201 | — |
| GSK Investigational Site | Greenbelt | Maryland | 20770 | — |
| GSK Investigational Site | Owings Mills | Maryland | 21117 | — |
| GSK Investigational Site | Rockville | Maryland | 20850 | — |
| GSK Investigational Site | Towson | Maryland | 21204 | — |
| GSK Investigational Site | Boston | Massachusetts | 02115 | — |
| GSK Investigational Site | Braintree | Massachusetts | 02184 | — |
| GSK Investigational Site | Haverhill | Massachusetts | 01830 | — |
| GSK Investigational Site | Milford | Massachusetts | 01757 | — |
| GSK Investigational Site | Newton | Massachusetts | 2462 | — |
| GSK Investigational Site | Springfield | Massachusetts | 01107 | — |
| GSK Investigational Site | Waltham | Massachusetts | 02453 | — |
| GSK Investigational Site | Watertown | Massachusetts | 02472 | — |
| GSK Investigational Site | West Yarmouth | Massachusetts | 02673 | — |
| GSK Investigational Site | Wocester | Massachusetts | 01608 | — |
| GSK Investigational Site | Ann Arbor | Michigan | 48106 | — |
| GSK Investigational Site | Detroit | Michigan | 48202 | — |
| GSK Investigational Site | Royal Oak | Michigan | 48073 | — |
| GSK Investigational Site | Saint Joseph | Michigan | 49085 | — |
| GSK Investigational Site | Chaska | Minnesota | 55318 | — |
| GSK Investigational Site | Edina | Minnesota | 55435 | — |
| GSK Investigational Site | Minneapolis | Minnesota | 55404 | — |
| GSK Investigational Site | Rochester | Minnesota | 55905 | — |
| GSK Investigational Site | Saint Cloud | Minnesota | 56303 | — |
| GSK Investigational Site | Hattiesburg | Mississippi | 39401 | — |
| GSK Investigational Site | Jackson | Mississippi | 39202 | — |
| GSK Investigational Site | Kansas City | Missouri | 64114 | — |
| GSK Investigational Site | Springfield | Missouri | 65807 | — |
| GSK Investigational Site | St Louis | Missouri | 63110-2539 | — |
| GSK Investigational Site | St Louis | Missouri | 63136 | — |
| GSK Investigational Site | St Louis | Missouri | 63141 | — |
| GSK Investigational Site | Billings | Montana | 59102 | — |
| GSK Investigational Site | Omaha | Nebraska | 68114 | — |
| GSK Investigational Site | Omaha | Nebraska | 68131 | — |
| GSK Investigational Site | Henderson | Nevada | 89014 | — |
| GSK Investigational Site | Las Vegas | Nevada | 89106 | — |
| GSK Investigational Site | Las Vegas | Nevada | 89148 | — |
| GSK Investigational Site | Reno | Nevada | 89502 | — |
| GSK Investigational Site | Reno | Nevada | 89511 | — |
| GSK Investigational Site | Lebanon | New Hampshire | 03756 | — |
| GSK Investigational Site | Edison | New Jersey | 08837 | — |
| GSK Investigational Site | Hackensack | New Jersey | 07601 | — |
| GSK Investigational Site | Lawrencevill | New Jersey | 08648 | — |
| GSK Investigational Site | Marlton | New Jersey | 08053 | — |
| GSK Investigational Site | Perth Amboy | New Jersey | 08861 | — |
| GSK Investigational Site | Voorhees Township | New Jersey | 08043 | — |
| GSK Investigational Site | West Orange | New Jersey | 07052 | — |
| GSK Investigational Site | Albany | New York | 12208 | — |
| GSK Investigational Site | Binghamton | New York | 13901 | — |
| GSK Investigational Site | Brooklyn | New York | 11234 | — |
| GSK Investigational Site | East Syracuse | New York | 13057 | — |
| GSK Investigational Site | Elmont | New York | 11003 | — |
| GSK Investigational Site | Endwell | New York | 13760 | — |
| GSK Investigational Site | Garden City | New York | 11530 | — |
| GSK Investigational Site | Great Neck | New York | 11021 | — |
| GSK Investigational Site | Mineola | New York | 11501 | — |
| GSK Investigational Site | New York | New York | 10016 | — |
| GSK Investigational Site | New York | New York | 10021 | — |
| GSK Investigational Site | Orchard Park | New York | 14127 | — |
| GSK Investigational Site | Poughkeepsie | New York | 12601 | — |
| GSK Investigational Site | Rochester | New York | 14642 | — |
| GSK Investigational Site | Staten Island | New York | 10304 | — |
| GSK Investigational Site | Syracuse | New York | 13210 | — |
| GSK Investigational Site | The Bronx | New York | 10467 | — |
| GSK Investigational Site | Cary | North Carolina | 27511 | — |
| GSK Investigational Site | Cary | North Carolina | 27518 | — |
| GSK Investigational Site | Chapel Hill | North Carolina | 27599-7600 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28211 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28262 | — |
| GSK Investigational Site | Charlotte, NC 28207 | North Carolina | 28207 | — |
| GSK Investigational Site | Concord | North Carolina | 28025 | — |
| GSK Investigational Site | Durham | North Carolina | 27710 | — |
| GSK Investigational Site | Greensboro | North Carolina | 27403 | — |
| GSK Investigational Site | Greenville | North Carolina | 27834 | — |
| GSK Investigational Site | Raleigh | North Carolina | 27607 | — |
| GSK Investigational Site | Raleigh | North Carolina | 27612 | — |
| GSK Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| GSK Investigational Site | Bismarck | North Dakota | 58501 | — |
| GSK Investigational Site | Cincinnati | Ohio | 45212 | — |
| GSK Investigational Site | Cincinnati | Ohio | 45219 | — |
| GSK Investigational Site | Columbus | Ohio | 43214 | — |
| GSK Investigational Site | Columbus | Ohio | 43220 | — |
| GSK Investigational Site | Columbus | Ohio | 43235 | — |
| GSK Investigational Site | Elyria | Ohio | 44035 | — |
| GSK Investigational Site | Kettering | Ohio | 45429 | — |
| GSK Investigational Site | Marion | Ohio | 43302 | — |
| GSK Investigational Site | Zanesville | Ohio | 43701 | — |
| GSK Investigational Site | Oklahoma City | Oklahoma | 73112 | — |
| GSK Investigational Site | Poca City | Oklahoma | 74601 | — |
| GSK Investigational Site | Tulsa | Oklahoma | 74146 | — |
| GSK Investigational Site | Oregon City | Oregon | 97045 | — |
| GSK Investigational Site | Portland | Oregon | 97205 | — |
| GSK Investigational Site | Portland | Oregon | 97210 | — |
| GSK Investigational Site | Portland | Oregon | 97213 | — |
| GSK Investigational Site | Springfield | Oregon | 97477 | — |
| GSK Investigational Site | Bala-Cynwyd | Pennsylvania | 19004 | — |
| GSK Investigational Site | Bryn Mawr | Pennsylvania | 19010 | — |
| GSK Investigational Site | Camp Hill | Pennsylvania | 17011 | — |
| GSK Investigational Site | Harrisburg | Pennsylvania | 17110 | — |
| GSK Investigational Site | Hershey | Pennsylvania | 17033-0850 | — |
| GSK Investigational Site | Lancaster | Pennsylvania | 17601 | — |
| GSK Investigational Site | Lancaster | Pennsylvania | 17604 | — |
| GSK Investigational Site | Monroeville | Pennsylvania | 15146 | — |
| GSK Investigational Site | Newton | Pennsylvania | 18940 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19141 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19144 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19152 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15215 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15232 | — |
| GSK Investigational Site | Rosemont | Pennsylvania | 19010 | — |
| GSK Investigational Site | Sellersville | Pennsylvania | 18960 | — |
| GSK Investigational Site | State College | Pennsylvania | 16801 | — |
| GSK Investigational Site | Cranston | Rhode Island | 02920 | — |
| GSK Investigational Site | Providence | Rhode Island | 02904 | — |
| GSK Investigational Site | West Warwick | Rhode Island | 02893 | — |
| GSK Investigational Site | Charleston | South Carolina | 29425 | — |
| GSK Investigational Site | Greenville | South Carolina | 29650 | — |
| GSK Investigational Site | Greer | South Carolina | 29651 | — |
| GSK Investigational Site | Myrtle Beach | South Carolina | 29572 | — |
| GSK Investigational Site | Simpsonville | South Carolina | 29681 | — |
| GSK Investigational Site | Fort Pierre | South Dakota | 57501 | — |
| GSK Investigational Site | Germantown | Tennessee | 38138 | — |
| GSK Investigational Site | Knoxville | Tennessee | 37920 | — |
| GSK Investigational Site | Memphis | Tennessee | 38119 | — |
| GSK Investigational Site | Nashville | Tennessee | 37209 | — |
| GSK Investigational Site | Nashville | Tennessee | 37232-2765 | — |
| GSK Investigational Site | Amarillo | Texas | 79106 | — |
| GSK Investigational Site | Arlington | Texas | 76017 | — |
| GSK Investigational Site | Austin | Texas | 78757 | — |
| GSK Investigational Site | Dallas | Texas | 75216 | — |
| GSK Investigational Site | Dallas | Texas | 75230 | — |
| GSK Investigational Site | Dallas | Texas | 75231 | — |
| GSK Investigational Site | Dallas | Texas | 75234 | — |
| GSK Investigational Site | Dallas | Texas | 75235 | — |
| GSK Investigational Site | Fort Worth | Texas | 76104 | — |
| GSK Investigational Site | Fort Worth | Texas | 76107 | — |
| GSK Investigational Site | Houston | Texas | 77024 | — |
| GSK Investigational Site | Houston | Texas | 77030 | — |
| GSK Investigational Site | San Antonio | Texas | 78229 | — |
| GSK Investigational Site | Texarkana | Texas | 75503 | — |
| GSK Investigational Site | Salt Lake City | Utah | 84107 | — |
| GSK Investigational Site | South Burlington | Vermont | 05403 | — |
| GSK Investigational Site | Alexandria | Virginia | 22302 | — |
| GSK Investigational Site | Charlottesville | Virginia | 22911 | — |
| GSK Investigational Site | Fairfax | Virginia | 22031 | — |
| GSK Investigational Site | Harrisonburg | Virginia | 22801 | — |
| GSK Investigational Site | Mechanicsville | Virginia | 23116 | — |
| GSK Investigational Site | Norfolk | Virginia | 23502 | — |
| GSK Investigational Site | Richmond | Virginia | 23249 | — |
| GSK Investigational Site | Salem | Virginia | 24153 | — |
| GSK Investigational Site | Virginia Beach | Virginia | 23454 | — |
| GSK Investigational Site | Graham | Washington | 98338 | — |
| GSK Investigational Site | Seattle | Washington | 98101 | — |
| GSK Investigational Site | Seattle | Washington | 98122 | — |
| GSK Investigational Site | Seattle | Washington | 98133 | — |
| GSK Investigational Site | Seattle | Washington | 98166 | — |
| GSK Investigational Site | Seattle | Washington | 98195 | — |
| GSK Investigational Site | Spokane | Washington | 99202 | — |
| GSK Investigational Site | Tacoma | Washington | 98405 | — |
| GSK Investigational Site | Tacoma | Washington | 98431 | — |
| GSK Investigational Site | Tacoma | Washington | 98499 | — |
| GSK Investigational Site | Madison | Wisconsin | 53715 | — |
| GSK Investigational Site | Milwaukee | Wisconsin | 53209 | — |
| GSK Investigational Site | Milwaukee | Wisconsin | 53215 | — |
| GSK Investigational Site | Cheyenne | Wyoming | 82001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 635 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00056407, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 22, 2016 · Synced Sep 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00056407 live on ClinicalTrials.gov.