- Conditions
- Familial Chylomicronemia, High Risk Severe Hypertriglyceridemia (SHTG)
- Interventions
- Plozasiran
- Drug
- Lead sponsor
- Arrowhead Pharmaceuticals
- Industry
- Eligibility
- 15 Years and older
- U.S. locations
- 1
- States / cities
- Pasadena, California
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–5
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- Conditions
- Severe Hypertriglyceridemia (sHTG)
- Interventions
- evinacumab, Placebo
- Drug
- Lead sponsor
- Regeneron Pharmaceuticals
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 9
- States / cities
- Boca Raton, Florida • Atlanta, Georgia • Kansas City, Kansas + 6 more
- Conditions
- Severe Hypertriglyceridemia
- Interventions
- Olezarsen
- Drug
- Lead sponsor
- Ionis Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 885 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 65
- States / cities
- Los Angeles, California • San Diego, California • Tarzana, California + 53 more
- Conditions
- Cardiovascular, Metabolic Disease, Dyslipidemias, Lipid Disorder, Hypertriglyceridemia, Heterozygous Familial Hypercholesterolemia (HeFH), Homozygous Familial Hypercholesterolemia (HoFH), Severe Hypertriglyceridemia (sHTG), Mixed Hyperlipemia, Hypercholesterolaemia
- Interventions
- CTX310
- Drug
- Lead sponsor
- CRISPR Therapeutics AG
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 9
- States / cities
- Hialeah, Florida • Jacksonville, Florida • Orlando, Florida + 6 more
- Conditions
- Severe Hypertriglyceridemia
- Interventions
- Pegozafermin, Placebo
- Drug
- Lead sponsor
- 89bio, Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 369 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 73
- States / cities
- Chandler, Arizona • Peoria, Arizona • Tucson, Arizona + 65 more