Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:40 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 232 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Severe Obesity Clear all

Conditions: Adolescent Obesity
Interventions: Lifestyle Modification Therapy (LSMT), Phentermine Pill, Topiramate Pill, Placebo; Behavioral · Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 12 Years to 17 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Morbid Obesity, Surgery, General Anesthesia
Interventions: Higher PEEP, Lower PEEP; Procedure
Lead sponsor: Technische Universität Dresden; Other
Eligibility: 18 Years and older
Enrollment: 2,013 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 2
States / cities: Boston, Massachusetts • Rochester, Minnesota

Conditions: Morbid Obesity
Interventions: LAGB & LGCP; Procedure
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Syosset, New York

Conditions: Atrial Fibrillation, Obesity, Anticoagulants
Interventions: Apixaban; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 107,383 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity and Diabetes Mellitus, Type 2
Interventions: JNJ-64565111 Dose Level 1, JNJ-64565111 Dose Level 2, JNJ-64565111 Dose Level 3, Placebo; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 27
States / cities: Birmingham, Alabama • Los Angeles, California • Rancho Cucamonga, California + 20 more

Conditions: Obesity, Morbid
Interventions: Not listed
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Weston, Florida

Conditions: Anastomotic Stricture, Morbid Obesity
Interventions: Esomeprazole; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Morbid Obesity, Insulin Resistance, Non-Alcoholic Fatty Liver Disease
Interventions: Not listed
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Morbid Obesity
Interventions: Plication; Procedure
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Severe Obesity, Obesity, BMI Greater Than 30
Interventions: Tirzepatide, Standard of Care post-gastric bypass; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 25 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Morbid Obesity
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Morbid Obesity, Metabolic Disease
Interventions: Laparoscopic Roux-en-Y Gastric Bypass; Procedure
Lead sponsor: Wyeth is now a wholly owned subsidiary of Pfizer; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 10
States / cities: Irvine, California • Orange, California • Atlanta, Georgia + 6 more

Conditions: Morbid Obesity
Interventions: NOTES toolbox; Device
Lead sponsor: Ethicon Endo-Surgery; Industry
Eligibility: 21 Years to 60 Years · Female only
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Morbid Obesity, Hyperglycemia, Diabetes Mellitus
Interventions: Observational; Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: San Diego, California

Conditions: Obesity, Major Depressive Disorder, Dysthymic Disorder, Cardiovascular Disease
Interventions: Behavior Modification for Weight Loss, Alternative Approach to Weight Loss, Cognitive-Behavior Therapy for Depression, Depression Support and Education; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Epidural Anesthesia, Spinal Ultrasound, Obesity
Interventions: Palpation, Ultrasound; Procedure · Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 45 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Physical Activity, Exercise, Body Composition
Interventions: Mentoring to be Active plus Family, Tracking Health and Fitness; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 11 Years and older
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Obesity
Interventions: In-Person weight loss, FIT weight loss, FIT-BT weight loss; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years to 55 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Morbid Obesity
Interventions: Not listed
Lead sponsor: University of California, Davis; Other
Eligibility: Not listed
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2012
U.S. locations: 2
States / cities: Sacramento, California • Reno, Nevada

Conditions: Obesity
Interventions: Telehealth Encounter; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 12 Years to 18 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Cincinnati, Indiana

Conditions: Psoriasis, Obesity
Interventions: Ixekizumab, Tirzepatide; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 281 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 68
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 57 more

Conditions: Morbid Obesity
Interventions: Laparoscopic Greater Curvature Plication; Procedure
Lead sponsor: Singh, Kuldeep, M.D., P.A.; Individual
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Severe Obesity
Interventions: Weight loss with pharmacotherapy, Weight loss without pharmacotherapy; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 12 Years to 17 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Obesity, Mental Disorders, Severe
Interventions: ACHIEVE; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

SMART Use of Medication for the Treatment of Adolescent Severe Obesity

Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients

Weight Loss & Comorbidity Resolution With LAGB Alone vs. LAGB With Gastric Plication

Effectiveness And Safety Of Oral Anticoagulants Among Obese Patients With Non-Valvular A-Fib In VA Patients With Medicare

A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus

BAriatric Surgery Induced Chromosomal Change

Study of Proton Pump Inhibitors (PPI) to Prevent Strictures After Gastric Bypass Surgery

Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery

Gastric Plication and Banding

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

Follow-up of Adolescent Bariatric Surgery

Study Evaluating Metabolic Syndrome in Subjects Undergoing Gastric Bypass Bariatric Syndrome

Laparoscopic Sleeve Gastrectomy With Endoscopic Visualization

Characteristics of Dendritic Cells Before and After Gastric Banding

Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD)

Utility of Ultrasound in Identification of Midline and Placement of Epidural in Severely Obese Parturients

Mentoring to be Active for Rural Appalachia Children

Comparison of a Technology-based System and an In-person Behavioral Weight Loss Intervention in the Severely Obese

Neurohumoral Control of Intestinal Electrical and Mechanical Activity

Healthy Weight for Teens

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

Resolution of Comorbidities & Safety and Efficacy of Greater Curvature Plication in Obese Patients

Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity

Adapted ACHIEVE Curriculum for Community Mental Health Settings