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ClinicalTrials.gov public records Last synced May 22, 2026, 3:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Severe Obesity Clear all
Completed Phase 1 Interventional
View directory record Official record
Conditions
Morbid Obesity, Vitamin D Deficiency
Interventions
vitamin D3 (Replesta), vitamin D
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 60 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced May 22, 2026, 3:51 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Bone Loss, Bone Density, Gastric Bypass, Bariatric Surgery
Interventions
Not listed
Lead sponsor
Gundersen Lutheran Medical Foundation
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 6, 2015 · Synced May 22, 2026, 3:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
View directory record Official record
Conditions
Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2021 · Synced May 22, 2026, 3:51 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Morbid Obesity, Noninvasive Ventilation, Deep Sedation
Interventions
High flow nasal cannula, Nasal Cannula
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced May 22, 2026, 3:51 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Physical Activity, Exercise, Body Composition
Interventions
Mentoring to be Active plus Family, Tracking Health and Fitness
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
11 Years and older
Enrollment
432 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Obesity, Morbid Obesity
Interventions
Transcend II Model 8848
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years to 65 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
8
States / cities
Washington D.C., District of Columbia • Gainsville, Florida • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Morbid Obesity, Cesarean Delivery Affecting Fetus
Interventions
CPAP
Device
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced May 22, 2026, 3:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Morbid Obesity, Endometrial Pathology, Menstrual Irregularities
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced May 22, 2026, 3:51 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Obesity, Childhood Obesity
Interventions
Dietary Fiber Supplement
Dietary Supplement
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced May 22, 2026, 3:51 AM EDT
Withdrawn No phase listed Observational
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
William Beaumont Army Medical Center
Federal
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced May 22, 2026, 3:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Obesity
Interventions
CP-945,598
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Anaheim, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2009 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparoscopic Gastric Plication
Procedure
Lead sponsor
Ponce, Jaime, M.D.
Individual
Eligibility
18 Years to 60 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Dalton, Georgia • Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced May 22, 2026, 3:51 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Pro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene Mutations
Interventions
Not listed
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
2 Years and older
Enrollment
5,966 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
48
States / cities
Birmingham, Alabama • Chandler, Arizona • Mesa, Arizona + 38 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced May 22, 2026, 3:51 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Morbid Obesity, Weight Reduction
Interventions
Decider Guider: Weight Loss
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
Interventions
Reduction of Ultra-processed foods
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced May 22, 2026, 3:51 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Childhood Obesity, Morbid Obesity
Interventions
Transcriptome profiling
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
2 Years to 20 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
2
States / cities
Boston, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Morbid Obesity
Interventions
Adjustable Gastric Band
Device
Lead sponsor
Kirk Reichard
Other
Eligibility
14 Years to 19 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced May 22, 2026, 3:51 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Bardet Biedl Syndrome (BBS), Alström Syndrome (AS)
Interventions
Setmelanotide, Placebo
Drug
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
6 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
6
States / cities
San Diego, California • Springfield, Massachusetts • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced May 22, 2026, 3:51 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Morbid Obesity
Interventions
Endolumik Gastric Calibration Tube (EGCT)
Device
Lead sponsor
Endolumik, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced May 22, 2026, 3:51 AM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2021 · Synced May 22, 2026, 3:51 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Morbid Obesity
Interventions
Observational Study
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 80 Years
Enrollment
4,785 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced May 22, 2026, 3:51 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Overweight and Obesity, Severe Obesity
Interventions
Connect for Health
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 12 Years
Enrollment
19,304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Denver, Colorado • Boston, Massachusetts • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced May 22, 2026, 3:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Obesity, Morbid, Time Restricted Eating, Pregnancy Weight Gain
Interventions
Time Restricted Eating
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced May 22, 2026, 3:51 AM EDT