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Completed No phase listed Observational

Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers

ClinicalTrials.gov ID: NCT02849977

Public ClinicalTrials.gov record NCT02849977. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 7, 2026, 11:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this screening study is to identify people who have a rare genetic cause of obesity - specifically three genetic variants (a change in the DNA structure) of the POMC, PCSK1 and LepR genes that are currently known to result in obesity. This screening study will not include any investigational drugs. You will be asked to provide a DNA sample and answer some questions about your medical history and hunger.

Study identification

NCT ID
NCT02849977
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Enrollment
5,966 participants

Conditions and interventions

Eligibility (public fields only)

Age range
2 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 27, 2016
Primary completion
Jun 8, 2020
Completion
Jun 8, 2020
Last update posted
Nov 14, 2022

2016 – 2020

United States locations

U.S. sites
48
U.S. states
22
U.S. cities
41
Facility City State ZIP Site status
Synexus Clinical Research US, Inc. - Simon Williamson Clinic, PC Birmingham Alabama 35211
Synexus Clinical Research US, Inc. - Phoenix Southeast Chandler Arizona 85224
Clinical Research Advantage Inc. Mesa Arizona
Tucson Neuroscience Research - M3 Wake Research Tucson Arizona 85710
Not listed Encino California 91316
PRI, LLC - Los Alamitos - M3 Wake Research Los Alamitos California 90720
Axis Clinical Trails Los Angeles California
Axis Clinical Trials Los Angeles California
PRI, LLC - Newport Beach - M3 Wake Research Newport Beach California 92660
Nemours Foundation Alfred Dupont Children's Hospital Wilmington Delaware 19803
Children's National Medical Center Washington D.C. District of Columbia 20010
University of Florida Gainesville Florida 32610
South Florida Clinical Trials Hialeah Florida
Translational Research Inst. for Metabolism and Diabetes Orlando Florida 32804
Nemours Children's Hospital Orlando Florida 32827
Palm Harbor Medical Associates - BTC - PPDS Palm Harbor Florida 34684
Synexus Clinical Research US, Inc. - St. Petersburg Pinellas Park Florida 33781
Synexus Clinical Research US, Inc. - Chicago Chicago Illinois 60602
Maine Medical Partners Pediatric Specialty Care Portland Maine 4102
Baystate Children's Hospital, Division of Pediatric Endocrinology Springfield Massachusetts
Helen DeVos Children's Hospital Healthy Weight Center Grand Rapids Michigan 49503
Synexus Clinical Research US, Inc. - West Florissant Internists Bridgeton Missouri 63044
Impact Clinical Trials - Las Vegas Las Vegas Nevada
University of New Mexico Albuquerque New Mexico
New York Clinical Trials-Brooklyn Brooklyn New York
Division of Endocrinology/Diabetes Amanda House Buffalo New York 14203
Cohen Children's Medical Center of NY Lake Success New York 11042
NYU Langone Medical Center New York New York 10016
Columbia University New York New York 10032
New York Clinical Trials-Manhattan New York New York
UNC Health Care - NC Children's Specialty Clinic Chapel Hill North Carolina 27514-4220
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599
Duke University Hospital Durham North Carolina 27705
Synexus Clinical Research US, Inc. - Akron Akron Ohio 44311
Synexus Clinical Research US, Inc. - Cincinnati Cincinnati Ohio 45236
Nationwide Children's Hospital, Center for Healthy Weight and Nutrition Columbus Ohio 43205
Synexus Clinical Research US, Inc. - Columbus Columbus Ohio 43212
Synexus Clinical Research US, Inc. - Centennial Health, PC - Oklahoma City Oklahoma 73111
Synexus Clinical Research US, Inc. - Primary Care Associates Anderson South Carolina 29621
University of Tennesseee Health Science Center Memphis Tennessee 38103
Medical Research Center of Memphis, LLC - M3 Wake Research Memphis Tennessee 38120
Vanderbilt University Nashville Tennessee 37232
Texas Tech University Health Sciences Center Amarillo Texas 79106
Synexus - Synexus US, LP - Dallas Dallas Texas 75234
Global Medical Research - M3 Wake Research DeSoto Texas 75115
Synexus Clinical Research US, Inc. - San Antonio San Antonio Texas 78229
University of Utah, Department of Surgery Salt Lake City Utah 84132
Seattle Children's Hospital Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02849977, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 14, 2022 · Synced Sep 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02849977 live on ClinicalTrials.gov.

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