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Completed No phase listed Observational

Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers

ClinicalTrials.gov ID: NCT02849977

Public ClinicalTrials.gov record NCT02849977. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 3:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this screening study is to identify people who have a rare genetic cause of obesity - specifically three genetic variants (a change in the DNA structure) of the POMC, PCSK1 and LepR genes that are currently known to result in obesity. This screening study will not include any investigational drugs. You will be asked to provide a DNA sample and answer some questions about your medical history and hunger.

Study identification

NCT ID
NCT02849977
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Enrollment
5,966 participants

Conditions and interventions

Eligibility (public fields only)

Age range
2 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 28, 2016 (Actual)
Primary completion
Jun 9, 2020 (Actual)
Completion
Jun 9, 2020 (Actual)
Last update posted
Nov 15, 2022

2016 – 2020

United States locations

U.S. sites
48
U.S. states
22
U.S. cities
41
Facility City State ZIP Site status
Synexus Clinical Research US, Inc. - Simon Williamson Clinic, PC Birmingham Alabama 35211 —
Synexus Clinical Research US, Inc. - Phoenix Southeast Chandler Arizona 85224 —
Clinical Research Advantage Inc. Mesa Arizona — —
Tucson Neuroscience Research - M3 Wake Research Tucson Arizona 85710 —
Not listed Encino California 91316 —
PRI, LLC - Los Alamitos - M3 Wake Research Los Alamitos California 90720 —
Axis Clinical Trails Los Angeles California — —
Axis Clinical Trials Los Angeles California — —
PRI, LLC - Newport Beach - M3 Wake Research Newport Beach California 92660 —
Nemours Foundation Alfred Dupont Children's Hospital Wilmington Delaware 19803 —
Children's National Medical Center Washington D.C. District of Columbia 20010 —
University of Florida Gainesville Florida 32610 —
South Florida Clinical Trials Hialeah Florida — —
Translational Research Inst. for Metabolism and Diabetes Orlando Florida 32804 —
Nemours Children's Hospital Orlando Florida 32827 —
Palm Harbor Medical Associates - BTC - PPDS Palm Harbor Florida 34684 —
Synexus Clinical Research US, Inc. - St. Petersburg Pinellas Park Florida 33781 —
Synexus Clinical Research US, Inc. - Chicago Chicago Illinois 60602 —
Maine Medical Partners Pediatric Specialty Care Portland Maine 4102 —
Baystate Children's Hospital, Division of Pediatric Endocrinology Springfield Massachusetts — —
Helen DeVos Children's Hospital Healthy Weight Center Grand Rapids Michigan 49503 —
Synexus Clinical Research US, Inc. - West Florissant Internists Bridgeton Missouri 63044 —
Impact Clinical Trials - Las Vegas Las Vegas Nevada — —
University of New Mexico Albuquerque New Mexico — —
New York Clinical Trials-Brooklyn Brooklyn New York — —
Division of Endocrinology/Diabetes Amanda House Buffalo New York 14203 —
Cohen Children's Medical Center of NY Lake Success New York 11042 —
NYU Langone Medical Center New York New York 10016 —
Columbia University New York New York 10032 —
New York Clinical Trials-Manhattan New York New York — —
UNC Health Care - NC Children's Specialty Clinic Chapel Hill North Carolina 27514-4220 —
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 —
Duke University Hospital Durham North Carolina 27705 —
Synexus Clinical Research US, Inc. - Akron Akron Ohio 44311 —
Synexus Clinical Research US, Inc. - Cincinnati Cincinnati Ohio 45236 —
Nationwide Children's Hospital, Center for Healthy Weight and Nutrition Columbus Ohio 43205 —
Synexus Clinical Research US, Inc. - Columbus Columbus Ohio 43212 —
Synexus Clinical Research US, Inc. - Centennial Health, PC - Oklahoma City Oklahoma 73111 —
Synexus Clinical Research US, Inc. - Primary Care Associates Anderson South Carolina 29621 —
University of Tennesseee Health Science Center Memphis Tennessee 38103 —
Medical Research Center of Memphis, LLC - M3 Wake Research Memphis Tennessee 38120 —
Vanderbilt University Nashville Tennessee 37232 —
Texas Tech University Health Sciences Center Amarillo Texas 79106 —
Synexus - Synexus US, LP - Dallas Dallas Texas 75234 —
Global Medical Research - M3 Wake Research DeSoto Texas 75115 —
Synexus Clinical Research US, Inc. - San Antonio San Antonio Texas 78229 —
University of Utah, Department of Surgery Salt Lake City Utah 84132 —
Seattle Children's Hospital Seattle Washington 98105 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02849977, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 15, 2022 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02849977 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →