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Showing 1–9 of 9 matching trials from the live ClinicalTrials.gov search.
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Conditions
Infertility
Interventions
ICSI
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
7 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Conditions
DNA Damage, DNA Strand Breaks, Sperm DNA Fragmentation
Interventions
sperm separation device
Device
Lead sponsor
Richard Kordus, PhD, HCLD (ABB)
Other
Eligibility
18 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Impact of Escitalopram on Sperm DNA Fragmentation

NCT03527043
Conditions
Sperm DNA Fragmentation, Infertility, Male
Interventions
Escitalopram, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
35 Years to 40 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Basking Ridge, New Jersey • Allentown, Pennsylvania
Conditions
Infertility (IVF Patients), Oocyte Competence, Sperm DNA Fragmentation, Paternal Age, Sperm Selection
Interventions
Microfluidic sperm separation device, Density grade centrifugation
Device · Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 41 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Conditions
Observe Effect of Antioxidant on Sperm DNA Fragmention
Interventions
Natural Antioxidant supplement
Dietary Supplement
Lead sponsor
Colorado Center for Reproductive Medicine
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
54 participants
Timeline
2018 – 2022
U.S. locations
1
States / cities
Lone Tree, Colorado
Active, not recruiting Not applicable Interventional

HELIOS: Human Embryo Illumination to Enhance Development

NCT07311928
Conditions
IVF Outcomes
Interventions
Photobiomodulation
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility,Male, Vitamin D Deficiency
Interventions
Vitamin D
Diagnostic Test
Lead sponsor
Sanford Health
Other
Eligibility
21 Years to 56 Years · Male only
Enrollment
230 participants
Timeline
2019 – 2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sperm Selection by Microfluidic Separation Improves Embryo Quality

NCT03085433
Conditions
Sperm DNA Fragmentation, Embryo Quality, Fertility Disorders, Infertility, Infertility, Male, Infertility Unexplained
Interventions
Microfluidic Sperm Sorting, in vitro fertilization
Device · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Francisco, California