- Conditions
- Status Epilepticus
- Interventions
- Quality improvement bundle, Quality improvement bundle and local PDSA cycles with central support, Quality improvement bundle and local PDSA cycles without central support
- Other
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- 30 Days to 18 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Status Epilepticus, Refractory Status Epilepticus
- Interventions
- Transcranial Direct Current Stimulation
- Device
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Status Epilepticus
- Interventions
- propofol, thiopental/pentobarbital
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Refractory Status Epilepticus
- Interventions
- Perampanel
- Drug
- Lead sponsor
- Wayne State University
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Neonatal Encephalopathy
- Interventions
- Epilog device
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- Up to 30 Days
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Refractory Epilepsy
- Interventions
- Traditional Treatment (Group T), Ketamine Infusion (Group K)
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 100 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Electrical Status Epilepticus of Slow-Wave Sleep
- Interventions
- Epidiolex 100 mg/mL Oral Solution, Placebo
- Drug · Other
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Lake Success, New York
- Conditions
- Status Epilepticus, Coma
- Interventions
- Rapid Response EEG
- Device
- Lead sponsor
- Children's Hospital at Montefiore
- Other
- Eligibility
- 2 Years to 18 Years
- Enrollment
- 60 participants
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus, Febrile Infection-Related Epilepsy Syndrome (FIRES)
- Interventions
- Anakinra, Tocilizumab, Standard medical treatment
- Drug · Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 2 Years and older
- Enrollment
- 438 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 25
- States / cities
- Phoenix, Arizona • Aurora, Colorado • New Haven, Connecticut + 17 more
- Conditions
- Status Epilepticus
- Interventions
- Midazolam, Seizalam
- Combination Product · Drug
- Lead sponsor
- Rafa Laboratories
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Raleigh, North Carolina
- Conditions
- Stereotypical Prolonged Seizures
- Interventions
- Staccato alprazolam
- Drug
- Lead sponsor
- UCB Biopharma SRL
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 53
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Little Rock, Arkansas + 40 more
- Conditions
- Epilepsy, Status Epilepticus
- Interventions
- levetiracetam, lacosamide, Ketamine, Phenobarbital
- Drug
- Lead sponsor
- Mid-Atlantic Epilepsy and Sleep Center, LLC
- Other
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC), Subarachnoid Hemorrhage, Aneurysmal, Ischemic Stroke, Intracerebral Hemorrhage
- Interventions
- Not listed
- Lead sponsor
- University of Alberta
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 512 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky • Columbus, Ohio
- Conditions
- Super-refractory Status Epilepticus
- Interventions
- SAGE-547
- Drug
- Lead sponsor
- Supernus Pharmaceuticals, Inc.
- Industry
- Eligibility
- 2 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 17
- States / cities
- Birmingham, Alabama • Sarasota, Florida • Chicago, Illinois + 13 more
- Conditions
- Status Epilepticus, Seizure, Epilepsy, Refractory Status Epilepticus, Medically Resistant Status Epilepticus
- Interventions
- Ketogenic diet
- Dietary Supplement
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 9
- States / cities
- Phoenix, Arizona • Honolulu, Hawaii • Chicago, Illinois + 6 more
- Conditions
- Seizures
- Interventions
- Clinically indicated EEG monitoring.
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 1 Month to 18 Years
- Enrollment
- 2,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2028
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Status Epilepticus
- Interventions
- Levetiracetam (LEV) (60 mg/Kg) + 1 mg/kg Ketamine (KET), Levetiracetam (LEV) (60 mg/Kg) + 3 mg/kg Ketamine (KET), Levetiracetam (LEV) (60 mg/Kg)
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 1 Year and older
- Enrollment
- 770 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 52
- States / cities
- Tucson, Arizona • Los Angeles, California • Palo Alto, California + 31 more
- Conditions
- Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Intraventricular Hemorrhage, Nontraumatic Haemorrhage, Status Epilepticus
- Interventions
- Not listed
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5,000 participants
- Timeline
- 2014 – 2034
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Altered Mental Status, Generalized Nonconvulsive Seizure Disorder, Status-epilepticus
- Interventions
- Not listed
- Lead sponsor
- Bio-Signal Group Corp.
- Industry
- Eligibility
- 13 Years and older
- Enrollment
- 261 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Landau-Kleffner Syndrome, Status Epilepticus, Electrographic
- Interventions
- Diazepam, Acetazolamide
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 3 Years to 12 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Status Epilepticus, Electrographic, Coma
- Interventions
- Vigabatrin Only Product
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Super-Refractory Status Epilepticus
- Interventions
- SAGE-547, Placebo
- Drug
- Lead sponsor
- Supernus Pharmaceuticals, Inc.
- Industry
- Eligibility
- 2 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 100
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 76 more
- Conditions
- Benzodiazepine Refractory Status Epilepticus
- Interventions
- Fosphenytoin, Levetiracetam, Valproic acid
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 2 Years and older
- Enrollment
- 478 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 65
- States / cities
- Tucson, Arizona • Los Angeles, California • Sacramento, California + 33 more
- Conditions
- Epilepsy, Status Epilepticus, Seizures
- Interventions
- Not listed
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2030
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico