- Conditions
- Refractory Status Epilepticus
- Interventions
- Perampanel
- Drug
- Lead sponsor
- Wayne State University
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
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Showing 25–48
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- Conditions
- Epilepsy, Status Epilepticus
- Interventions
- Seizure Action Plan
- Other
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 1 Month to 21 Years
- Enrollment
- 288 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Status Epilepticus
- Interventions
- Midazolam, Seizalam
- Combination Product · Drug
- Lead sponsor
- Rafa Laboratories
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Raleigh, North Carolina
- Conditions
- Seizures
- Interventions
- Clinically indicated EEG monitoring.
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 1 Month to 18 Years
- Enrollment
- 2,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2028
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Mitochondrial Diseases, Drug Resistant Epilepsy, Leigh Disease, Leigh Syndrome, Mitochondrial Encephalopathy (MELAS), Pontocerebellar Hypoplasia Type 6 (PCH6), Alpers Disease, Alpers Syndrome
- Interventions
- Vatiquinone, Placebo
- Drug · Other
- Lead sponsor
- PTC Therapeutics
- Industry
- Eligibility
- Up to 20 Years
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 12
- States / cities
- San Diego, California • Stanford, California • New Haven, Connecticut + 7 more
- Conditions
- Anesthesia, Psychomotor Status
- Interventions
- Not listed
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Sars-CoV2, Severe Neurologic Injury, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Traumatic Brain Injury, Status Epilepticus
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Epilepsia Partialis Continua, Kojewnikov's Epilepsy, Epilepsy
- Interventions
- Clobazam, Clonazepam, Lorazepam
- Drug
- Lead sponsor
- The Cooper Health System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Camden, New Jersey
- Conditions
- Benzodiazepine Refractory Status Epilepticus
- Interventions
- Fosphenytoin, Levetiracetam, Valproic acid
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 2 Years and older
- Enrollment
- 478 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 65
- States / cities
- Tucson, Arizona • Los Angeles, California • Sacramento, California + 33 more
- Conditions
- Neonatal Encephalopathy
- Interventions
- Epilog device
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- Up to 30 Days
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Status Epilepticus, Refractory Status Epilepticus
- Interventions
- Transcranial Direct Current Stimulation
- Device
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Electrical Status Epilepticus in Sleep
- Interventions
- ESES treated with clobazam
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 2 Years to 21 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Boston, Massachusetts
- Conditions
- Nonconvulsive Status Epilepticus, Seizures
- Interventions
- Ceribell Rapid Response EEG, Survey
- Device
- Lead sponsor
- Ceribell Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 164 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Chicago, Illinois • Boston, Massachusetts + 2 more
- Conditions
- Status Epilepticus
- Interventions
- lorazepam or diazepam
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 3 Months to 18 Years
- Enrollment
- 259 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 12
- States / cities
- Davis, California • Aurora, Colorado • Washington D.C., District of Columbia + 9 more
- Conditions
- Status Epilepticus
- Interventions
- Verbal Instructions Educational Intervention, Video Educational Intervention, Mannequin Educational Intervention
- Other
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 2 Years to 80 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Status Epilepticus
- Interventions
- propofol, thiopental/pentobarbital
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Status Epilepticus, Electrographic, Coma
- Interventions
- Vigabatrin Only Product
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Status Epilepticus
- Interventions
- Quality improvement bundle, Quality improvement bundle and local PDSA cycles with central support, Quality improvement bundle and local PDSA cycles without central support
- Other
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- 30 Days to 18 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Super-Refractory Status Epilepticus
- Interventions
- SAGE-547, Placebo
- Drug
- Lead sponsor
- Supernus Pharmaceuticals, Inc.
- Industry
- Eligibility
- 2 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 100
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 76 more
- Conditions
- Altered Mental Status, Generalized Nonconvulsive Seizure Disorder, Status-epilepticus
- Interventions
- Not listed
- Lead sponsor
- Bio-Signal Group Corp.
- Industry
- Eligibility
- 13 Years and older
- Enrollment
- 261 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Electrical Status Epilepticus of Slow-Wave Sleep
- Interventions
- Epidiolex 100 mg/mL Oral Solution, Placebo
- Drug · Other
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Lake Success, New York
- Conditions
- Status Epilepticus, Coma
- Interventions
- Rapid Response EEG
- Device
- Lead sponsor
- Children's Hospital at Montefiore
- Other
- Eligibility
- 2 Years to 18 Years
- Enrollment
- 60 participants
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Intraventricular Hemorrhage, Nontraumatic Haemorrhage, Status Epilepticus
- Interventions
- Not listed
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5,000 participants
- Timeline
- 2014 – 2034
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Status Epilepticus, Seizure, Epilepsy, Refractory Status Epilepticus, Medically Resistant Status Epilepticus
- Interventions
- Ketogenic diet
- Dietary Supplement
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 9
- States / cities
- Phoenix, Arizona • Honolulu, Hawaii • Chicago, Illinois + 6 more