- Conditions
- Cognition Disorders in Old Age, Mild Cognitive Impairment, Cognitive Decline
- Interventions
- Niagen, Placebo Comparator
- Dietary Supplement
- Lead sponsor
- Steven E Arnold, MD
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
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Showing 1–24
of 41
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Mild Cognitive Impairment, Subjective Memory Decline
- Interventions
- Tai Chi, Preventing Loss of Independence through Exercise (PLIE), Health and Wellness Education
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Subjective Cognitive Concerns, Mild Cognitive Impairment, Mild Behavioral Impairment, Healthy Aging
- Interventions
- AROMHA Brain Health Test
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Subjective Cognitive Decline
- Interventions
- Internet-based Mindfulness-Based Stress Reduction (iMBSR), Internet-based Lifestyle Education (iLifeEd)
- Behavioral
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Cognitive Impairment, Subjective Cognitive Decline, Mild Cognitive Impairment (MCI)
- Interventions
- Brain Health Together
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Mild Cognitive Impairment, Subjective Cognitive Impairment
- Interventions
- Ola Mau i ka Hula
- Behavioral
- Lead sponsor
- University of Hawaii
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 3
- States / cities
- Honolulu, Hawaii • Wailuku, Hawaii
- Conditions
- Mild Cognitive Impairment, Subjective Cognitive Impairment
- Interventions
- pSOPT, MLA
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Cognitive Decline
- Interventions
- Baduanjin Exercise, Cognitive Fitness Program
- Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 124 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Subjective Cognitive Decline
- Interventions
- Neurotrack Virtual Cognitive Health Program
- Behavioral
- Lead sponsor
- Evidation Health
- Industry
- Eligibility
- 60 Years to 75 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- San Mateo, California
- Conditions
- Subjective Memory Loss in Older Persons
- Interventions
- Cerefolin NAC (a medical food), Cerefolin NAC placebo
- Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Subjective Cognitive Impairment
- Interventions
- P-tau217, Standard of Care
- Diagnostic Test · Other
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 7,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Mild Cognitive Impairment
- Interventions
- Curcumin, aerobic yoga, non aerobic yoga, Placebo
- Drug · Behavioral · Dietary Supplement
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 1
- States / cities
- West Los Angeles, California
- Conditions
- Cognitively Normal Older Adults, Hypertension, Subjective Cognitive Decline, Family History of Dementia
- Interventions
- Angiotensin II Receptor Blockers (ARBs, losartan) and Calcium Channel Blockers (CCB, amlodipine), PCP
- Drug · Other
- Lead sponsor
- Rong Zhang
- Other
- Eligibility
- 60 Years to 85 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases, Dental Diseases, Hormone Disturbance, Neurocognitive Dysfunction
- Interventions
- Supplements and/or medical foods, Behavioral change support program, Food plan
- Dietary Supplement · Behavioral · Other
- Lead sponsor
- Metagenics, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Gig Harbor, Washington
- Conditions
- MCI, Subjective Cognitive Decline (SCD), Mild Behavioral Impairment
- Interventions
- Cognitive Remediation, Cognitive Remediation II
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 60 Years to 89 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases, Dental Diseases, Hormone Disturbance, Neurocognitive Dysfunction
- Interventions
- Not listed
- Lead sponsor
- Metagenics, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Gig Harbor, Washington
- Conditions
- Mild Cognitive Impairment, Subjective Cognitive Decline (SCD)
- Interventions
- VR sessions
- Device
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 55 Years to 90 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Subjective Cognitive Complaints, Mild Cognitive Impairment
- Interventions
- Personalized Web-based training for EMMA app, Motivational Interviewing: Clinician Support
- Behavioral
- Lead sponsor
- Washington State University
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Pullman, Washington
- Conditions
- Chemo Brain, Chemotherapy-related Cognitive Impairment, Chemo Fog, Breast Cancer, Chemobrain
- Interventions
- Transdermal nicotine, Placebo Transdermal Patch
- Drug · Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 35 Years to 80 Years · Female only
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Subjective Cognitive Decline (SCD)
- Interventions
- Green Activity Program
- Behavioral
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Bloomington, Indiana
- Conditions
- Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
- Interventions
- MBCT+w, ALED
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Aging
- Interventions
- Transcranial direct current stimulation
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 65 Years to 89 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Prodromal Alzheimer's Disease, Mild Cognitive Impairment, Subjective Cognitive Complaints
- Interventions
- Digital Memory Notebook (DMN) Application
- Behavioral
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Delirium, Cognitive Impairment, Health, Subjective, Sleep
- Interventions
- FAVoR Intervention
- Behavioral
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 178 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 3
- States / cities
- Miami, Florida • Tampa, Florida