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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:51 PM EDT

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Showing 1–24 of 1,852 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Surgical Complication Clear all
Completed No phase listed Observational

Neurologic Complications in Spinal Deformity Surgery - Extension

NCT02949245
View directory record Official record
Conditions
Adult Spinal Deformity
Interventions
Interventions
Procedure
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
18 Years to 80 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
5
States / cities
San Francisco, California • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 20, 2026, 4:51 PM EDT
Terminated Not applicable Interventional

Transcutaneous Autonomic Modulation in Thoracic Surgery

NCT02783157
View directory record Official record
Conditions
Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
Interventions
Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS), Sham LLVNS
Device
Lead sponsor
Duke University
Other
Eligibility
40 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 20, 2026, 4:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery

NCT03059602
View directory record Official record
Conditions
Pain, Postoperative
Interventions
No specific treatment based intervention-health measurement instrument
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Oct 20, 2026, 4:51 PM EDT
Recruiting Not applicable Interventional

VA Transitional Pain Service Study

NCT06223503
View directory record Official record
Conditions
Chronic Opioid Use
Interventions
Transitional Pain Service
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alternative Gingival De-Epithelialization Techniques

NCT05947305
View directory record Official record
Conditions
Recession, Gingival, Surgical Procedure, Unspecified, Graft Complication, Wound Heal
Interventions
Surgical Blade, Mucotome, Diamond Bur, Er:YAG Laser
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Anesthetics to Prevent Lung Injury in Cardiac Surgery

NCT02918877
View directory record Official record
Conditions
Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury, Postoperative Pulmonary Complications
Interventions
Sevoflurane, Propofol
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Phase 1Phase 2 Interventional

Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer

NCT00003930
View directory record Official record
Conditions
Bladder Cancer
Interventions
cisplatin, gemcitabine hydrochloride, paclitaxel, conventional surgery, radiation therapy
Drug · Procedure · Radiation
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2013
U.S. locations
210
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 166 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Phase 2 Interventional Results available

Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain

NCT01729728
View directory record Official record
Conditions
Postoperative Pain, Acute Pain
Interventions
Tapentadol
Drug
Lead sponsor
Grünenthal GmbH
Industry
Eligibility
2 Years to 17 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 20, 2026, 4:51 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine With Dexamethasone for Foot Surgery

NCT06465992
View directory record Official record
Conditions
Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
Interventions
Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Oct 20, 2026, 4:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.

NCT04746573
View directory record Official record
Conditions
Non-healing Wounds
Interventions
Natrox Topical Oxygen Therapy
Device
Lead sponsor
Inotec AMD Limited
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 20, 2026, 4:51 PM EDT
Active, not recruiting Not applicable Interventional

Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

NCT05063331
View directory record Official record
Conditions
Uterine Prolapse
Interventions
Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
7
States / cities
Jacksonville, Florida • Chicago, Illinois • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Phase 2 Interventional Results available

S0219, Combination Chemotherapy Followed By Observation or Surgery in Patients With Stage II or Stage III Cancer of the Urothelium

NCT00045630
View directory record Official record
Conditions
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
Interventions
carboplatin, gemcitabine, paclitaxel, surgery
Drug · Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
128
States / cities
Anchorage, Alaska • Glendale, Arizona • Mesa, Arizona + 89 more
Source: ClinicalTrials.gov public record
Updated May 27, 2013 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Not applicable Interventional Results available

S1011 Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer

NCT01224665
View directory record Official record
Conditions
Bladder Cancer
Interventions
therapeutic conventional surgery, therapeutic standard lymphadenectomy, therapeutic extended lymphadenectomy
Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years to 120 Years
Enrollment
658 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
29
States / cities
Los Angeles, California • Palo Alto, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 20, 2026, 4:51 PM EDT
Terminated Not applicable Interventional Results available

External Fixation Versus Splinting of Acute Calcaneus Fractures

NCT04063657
View directory record Official record
Conditions
Calcaneus Fracture
Interventions
External fixator, Splinting
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 69 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Oct 20, 2026, 4:51 PM EDT
Terminated Not applicable Interventional Results available

Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy

NCT00654641
View directory record Official record
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postoperative Activity Restrictions After Slings

NCT04552457
View directory record Official record
Conditions
Stress Urinary Incontinence, Patient Satisfaction, Surgery
Interventions
No activity restrictions, Activity restrictions
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 20, 2026, 4:51 PM EDT
Not yet recruiting Not applicable Interventional

Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision

NCT07844681
View directory record Official record
Conditions
Surgical Site Infection, Skin Cancer, Wound Healing
Interventions
Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure, Prolene Running Epidermal Suture Closure
Device · Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Improving Surgical Patient Outcomes Through Implementation of a SemiStructured Intraoperative Anesthesia Handoff Tool

NCT06533111
View directory record Official record
Conditions
Post-operative Complications
Interventions
Epic Health Record semi-structured handoff cognitive aid, Usual care
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 105 Years
Enrollment
3,763 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Not listed Early Phase 1 Interventional

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery

NCT06387303
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Methadone, Morphine
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Comparing the Effectiveness of Lung Expansion Therapy in Adult Human Subjects

NCT02892773
View directory record Official record
Conditions
Atelectasis
Interventions
Incentive Spirometry, EzPAP® Positive Airway Pressure
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 79 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Oct 20, 2026, 4:51 PM EDT
Active, not recruiting Not applicable Interventional

Postoperative VR for Recovery After Bariatric Surgery

NCT04754165
View directory record Official record
Conditions
Bariatric Surgery Candidate, Postoperative Pain, Postoperative Complications
Interventions
Virtual Reality Immersive Relaxation
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Completed No phase listed Observational

Susceptibility to Chronic Post-Traumatic Extremity Pain

NCT00672711
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 20, 2026, 4:51 PM EDT
Recruiting Not applicable Interventional

Early Versus Delayed Bathing of Orthopaedic Surgical Wounds

NCT06014411
View directory record Official record
Conditions
Surgical Wound, Post Operative Wound Infection
Interventions
Time to bathing (delayed), Time to bathing (early)
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 20, 2026, 4:51 PM EDT
Completed Phase 2 Interventional Results available

Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

NCT02035787
View directory record Official record
Conditions
Complex Atypical Hyperplasia, Endometrial Cancer
Interventions
Metformin
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 20, 2026, 4:51 PM EDT