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ClinicalTrials.gov public records Last synced May 22, 2026, 12:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–10 of 10 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Syndesmotic Injuries Clear all
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar, Ankle Fracture - Medial Malleolus, Maisonneuve's Fracture, Syndesmotic Injuries, Fibula Fracture
Interventions
Tourniquet
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced May 22, 2026, 12:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Ankle Injuries, Syndesmotic Injuries, Ankle Fractures
Interventions
Arthrex Tightrope, Synthes Fibulink
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced May 22, 2026, 12:33 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain, Achilles Tendon Rupture, Flexor Hallucis Longus on the Left, Flexor Hallucis Longus on the Right, Flexor Digitorum Longus on the Left, Flexor Digitorum Longus on the Right, Ankle Sprains
Interventions
Grappler Interference Screw System
Device
Lead sponsor
Paragon 28
Industry
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Worthington, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced May 22, 2026, 12:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Ankle Fractures, Bimalleolar Fractures, Syndesmotic Injuries, Bimalleolar Equivalent Fracture, Maisonneuve Fracture, Trimalleolar Fractures, Ankle Dislocation
Interventions
Early Weight Bearing, Normal Weight Bearing
Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
22 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced May 22, 2026, 12:33 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Displaced Ankle Fractures
Interventions
2D Fluoroscopy, 3D Fluoroscopy
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced May 22, 2026, 12:33 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Syndesmotic Injuries
Interventions
Arthrex Tightrope, Synthes Fibulink
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 5, 2024 · Synced May 22, 2026, 12:33 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Syndesmotic Injuries
Interventions
Arthrex InternalBrace
Device
Lead sponsor
St. Clair Orthopaedics
Other
Eligibility
18 Years to 105 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Saint Clair Shores, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 20, 2021 · Synced May 22, 2026, 12:33 AM EDT
Terminated Phase 2 Interventional Results available
View directory record Official record
Conditions
Ankle Injuries
Interventions
bupivacaine hydrochloride and betamethasone sodium phosphate, bupivacaine hydrochloride
Drug
Lead sponsor
Sanford Health
Other
Eligibility
16 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced May 22, 2026, 12:33 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain, Achilles Tendon Rupture, Flexor Hallucis Longus on the Left, Flexor Digitorum Longus on the Left, Ankle Sprains, Flexor Hallucis Longus on the Right, Flexor Digitorum Longus on the Right
Interventions
Grappler® Interference Screw System
Device
Lead sponsor
Paragon 28
Industry
Eligibility
Not listed
Enrollment
50 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Worthington, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced May 22, 2026, 12:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Syndesmotic Injuries, Ligament Rupture, Bimalleolar Fractures, Trimalleolar Fractures
Interventions
Tight rope fixation, Tight rope fixation with an anterior inferior tibiofibular ligament (AITFL) repair augmentation with an internal brace
Device
Lead sponsor
Vann Virginia Center for Orthopaedics dba Atlantic Orthopaedic Specialists
Other
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced May 22, 2026, 12:33 AM EDT