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Showing 25–41 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Thoracic Aortic Dissection Clear all
Completed Not applicable Interventional

Thoraflex™ Hybrid IDE Study

NCT02724072
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Dissection, Aortic Rupture
Interventions
Thoraflex™ Hybrid Device
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
12
States / cities
Palo Alto, California • Atlanta, Georgia • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Sep 17, 2026, 5:16 AM EDT
Approved For Marketing No phase listed Expanded access

Zenith® Dissection Endovascular System in the Treatment of Patients With Aortic Dissections

NCT02464943
View directory record Official record
Conditions
Aortic Dissection
Interventions
Endovascular Treatment (Zenith)
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
3
States / cities
Camden, New Jersey • Pittsburgh, Pennsylvania • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 17, 2026, 5:16 AM EDT
Active, not recruiting No phase listed Observational

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)

NCT05082454
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
Open repair
Device
Lead sponsor
JOTEC GmbH
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
3
States / cities
Danville, Pennsylvania • Houston, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes

NCT02213484
View directory record Official record
Conditions
Marfan Syndrome, Loeys-Dietz Syndrome, Thoracic Aortic Aneurysm and Dissection Syndromes, Ehlers-Danlos Type IV Syndrome, Turner Syndrome
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Days to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

NCT04471909
View directory record Official record
Conditions
Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
Interventions
NEXUS Aortic Stent Graft System
Device
Lead sponsor
Endospan Ltd.
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
31
States / cities
Birmingham, Alabama • La Jolla, California • Sacramento, California + 27 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cardiovascular Health Improvement Project

NCT02306200
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure, Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
Not listed
Enrollment
15,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2053
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Completed No phase listed Observational

Point-of-Care Focused Cardiac Ultrasound in Assessing the Thoracic Aorta

NCT01671618
View directory record Official record
Conditions
Aortic Aneurysm, Thoracic, Aortic Dissection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 29, 2016 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Not applicable Interventional Results available

Zenith® Dissection Clinical Trial

NCT01568320
View directory record Official record
Conditions
Aortic Dissection
Interventions
Endovascular Treatment (Zenith)
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Gainesville, Florida • Tampa, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts

NCT02323581
View directory record Official record
Conditions
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Thoracic, Aortic Dissection, Thoracoabdominal
Interventions
Endovascular treatment of Thoracoabdominal Aortic Aneurysm, Endovascular treatment of Aortic Arch Aneurysms
Device
Lead sponsor
Darren Schneider, M.D.
Other
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2033
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Active, not recruiting No phase listed Observational

Pathogenetic Basis of Aortopathy and Aortic Valve Disease

NCT03440697
View directory record Official record
Conditions
Aortopathies, Thoracic Aortic Aneurysm, Aortic Valve Disease, Thoracic Aortic Disease, Thoracic Aortic Dissection, Thoracic Aortic Rupture, Ascending Aortic Disease, Descending Aortic Disease, Ascending Aortic Aneurysm, Descending Aortic Aneurysm, Marfan Syndrome, Loeys-Dietz Syndrome, Vascular Ehlers-Danlos Syndrome, Shprintzen-Goldberg Syndrome, Turner Syndrome, PHACE Syndrome, Autosomal Recessive Cutis Laxa, Congenital Contractural Arachnodactyly, Arterial Tortuosity Syndrome, Bicuspid Aortic Valve-Associated Aortopathy, Bicuspid Aortic Valve, Familial Thoracic Aortic Aneurysm and Aortic Dissection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2030
U.S. locations
2
States / cities
Atlanta, Georgia • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Active, not recruiting Not applicable Interventional

Study of the RelayPro Thoracic Stent-Graft in Subjects With an Acute, Complicated Type B Aortic Dissection

NCT03033043
View directory record Official record
Conditions
Aortic Dissection Type B
Interventions
Relay Pro Stent-Graft
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
21
States / cities
Los Angeles, California • Aurora, Colorado • Hartford, Connecticut + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Not listed Not applicable Interventional

Trial of Exercise in Aortic Dissection Survivors

NCT05610462
View directory record Official record
Conditions
Thoracic Aortic Dissection
Interventions
Guided Exercise Training Program, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices

NCT02050113
View directory record Official record
Conditions
Complex Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aneurysms, Juxtarenal Aneurysms, Marfan Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, Aortic Arch Aneurysm
Interventions
Custom Made Fenestrated or Branched Stent Graft
Device
Lead sponsor
Andres Schanzer
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2030
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Feasibility of Endovascular Repair Of Ascending Aortic Pathologies

NCT02201589
View directory record Official record
Conditions
Aortic Dissection, Intramural Hematoma, Penetrating Ulcer, Pseudoaneurysm
Interventions
Endovascular repair with Valiant PS-IDE Stent Graft
Device
Lead sponsor
Rodney A. White, MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2033
U.S. locations
3
States / cities
Long Beach, California • Los Angeles, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies

NCT02043691
View directory record Official record
Conditions
Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Penetrating Aortic Ulcer, Aortic Arch Aneurysm, Aortic Dissection
Interventions
Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft, Surgeon-Modified Endograft
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

NCT07089576
View directory record Official record
Conditions
Aortic Arch Aneurysm, Aortic Arch Dissection, Chronic Aortic Dissection, Acute Aortic Dissection
Interventions
Arcevo™ LSA Hybrid Stent Graft System
Device
Lead sponsor
Artivion Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
21
States / cities
Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft

NCT02089607
View directory record Official record
Conditions
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
Interventions
CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
Device
Lead sponsor
Gustavo S Oderich
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2032
U.S. locations
3
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 17, 2026, 5:16 AM EDT