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ClinicalTrials.gov public records Last synced Oct 19, 2026, 7:49 PM EDT

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Showing 1–24 of 129 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tinnitus Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Nitrous Oxide Treatment for Tinnitus

NCT03365011
View directory record Official record
Conditions
Tinnitus
Interventions
Nitrous oxide gas for inhalation, Placebo gas for inhalation
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 14, 2018 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cochlear Promontory Stimulation for Treatment of Tinnitus

NCT03759834
View directory record Official record
Conditions
Tinnitus
Interventions
Cochlear promontory stimulation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 19, 2026, 7:49 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus

NCT04192773
View directory record Official record
Conditions
Tinnitus
Interventions
IV Lidocaine
Drug
Lead sponsor
D. Bradley Welling, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 19, 2026, 7:49 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Regulating Homeostatic Plasticity and the Physiological Response to rTMS

NCT03309696
View directory record Official record
Conditions
Tinnitus
Interventions
sham tDCS and sham rTMS, sham tDCS and active rTMS, active tDCS and active rTMS
Device
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 19, 2026, 7:49 PM EDT
Terminated Not applicable Interventional Results available

Effect of the Erchonia® HLS™ for the Relief of Tinnitus Symptoms

NCT05091060
View directory record Official record
Conditions
Tinnitus
Interventions
Erchonia HLS
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Vagus Auricular Stimulation for Tinnitus

NCT06821893
View directory record Official record
Conditions
Tinnitus
Interventions
Vibrational stimulation, Sham
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 2 Interventional Results available

rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study

NCT00886938
View directory record Official record
Conditions
Tinnitus
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), pilot study
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 16, 2014 · Synced Oct 19, 2026, 7:49 PM EDT
Completed No phase listed Observational

Exploring Voluntary Control of Tinnitus

NCT00973648
View directory record Official record
Conditions
Tinnitus
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 11, 2013 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Multi-Site Randomized Clinical Study of Tinnitus Treatment Methods

NCT00235807
View directory record Official record
Conditions
Tinnitus
Interventions
Tinnitus Masking, Tinnitus Retraining Therapy (TRT), Tinnitus Education (TED)
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 24, 2011 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 2 Interventional Results available

Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus

NCT03336398
View directory record Official record
Conditions
Tinnitus
Interventions
Ketamine Hydrochloride in saline
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 60 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 3 Interventional Results available

A Trial of Magnesium Dependent Tinnitus

NCT01273883
View directory record Official record
Conditions
Tinnitus
Interventions
Magnesium, Placebo
Dietary Supplement · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Oct 19, 2026, 7:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Neurobiological Similarities of Tinnitus and PTSD

NCT05981391
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Tinnitus
Interventions
resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry, Tinnitus Assessment, Otoscopy, Pure tone air and bone-conduction, Speech testing, Loudness Discomfort, Quick Speech in Noise Test, Distortion-Product Otoacoustic Emissions (DPOAE)
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 2 Interventional Results available

OTO-313 in Subjects With Unilateral Subjective Tinnitus

NCT04829214
View directory record Official record
Conditions
Subjective Tinnitus
Interventions
OTO-313, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
31
States / cities
Fresno, California • Torrance, California • Aurora, Colorado + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2023 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 2 Interventional

Comparison of Single Versus Repeat Doses of AM-101 in the Treatment of Acute Inner Ear Tinnitus

NCT01270282
View directory record Official record
Conditions
Tinnitus
Interventions
AM-101 0.81 mg/mL, Placebo
Drug
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
Gainsville, Florida • Kansas City, Kansas • Louisville, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Not applicable Interventional Results available

Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus

NCT03904264
View directory record Official record
Conditions
Tinnitus, Hearing Aids, Normal Hearing
Interventions
Receiver in the canal (RIC) hearing aids
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 19, 2026, 7:49 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Use of Modafinil in the Treatment of Tinnitus

NCT00591019
View directory record Official record
Conditions
Tinnitus
Interventions
Modafinil, Placebo
Drug · Other
Lead sponsor
University of Arkansas
Other
Eligibility
20 Years to 99 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 1Phase 2 Interventional Results available

OTO-313 in Subjects With Subjective Tinnitus

NCT03918109
View directory record Official record
Conditions
Tinnitus, Subjective
Interventions
OTO-313, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
16
States / cities
Los Angeles, California • San Diego, California • Colorado Springs, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 19, 2026, 7:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treating Tinnitus Using the Neuromonics Tinnitus Treatment Program: A Randomized, Double-blind Study

NCT02829073
View directory record Official record
Conditions
Tinnitus
Interventions
Neuromonics Tinnitus Treatment Program, Placebo Device
Device
Lead sponsor
United States Army Aeromedical Research Laboratory
Federal
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fort Rucker, Alabama
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 19, 2026, 7:49 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Exploration of Cortical Neural Network in Patients With Bothersome Tinnitus

NCT01385540
View directory record Official record
Conditions
Tinnitus
Interventions
Task-Based Functional Magnetic Resonance Imaging (fMRI)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 2, 2012 · Synced Oct 19, 2026, 7:49 PM EDT
Terminated Phase 3 Interventional

Open-Label, Long-Term Treatment Study, to Assess the Long-Term Safety and Tolerability and Efficacy of Neramexane in Patients With Subjective Tinnitus

NCT00827008
View directory record Official record
Conditions
Subjective Tinnitus
Interventions
Neramexane mesylate
Drug
Lead sponsor
Merz Pharmaceuticals GmbH
Industry
Eligibility
18 Years to 75 Years
Enrollment
821 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
31
States / cities
Tucson, Arizona • Burbank, California • Fresno, California + 27 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Micronutrients to Prevent Noise-induced Hearing Loss

NCT00808470
View directory record Official record
Conditions
Noise-Induced Hearing Loss
Interventions
beta-carotene, vitamins C and E, magnesium, Placebo
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 35 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Early Phase 1 Interventional

MRI Study of Noninvasive Transcranial Electrical Stimulation in Tinnitus

NCT03544359
View directory record Official record
Conditions
Tinnitus, Subjective
Interventions
Transcranial electrical stimulation (tES)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 19, 2026, 7:49 PM EDT
Not listed Not applicable Interventional

Evaluation of the OtoBand as a Treatment to Reduce the Perceived Loudness of Tinnitus

NCT04787653
View directory record Official record
Conditions
Tinnitus
Interventions
Otoband, Placebo
Device
Lead sponsor
Otolith Labs
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 19, 2026, 7:49 PM EDT
Completed Not applicable Interventional Results available

Multi-Site Evaluation of Progressive Tinnitus Management

NCT01015781
View directory record Official record
Conditions
Tinnitus
Interventions
Progressive Tinnitus Management, Wait List Control
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
West Haven, Connecticut • Portland, Oregon • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 19, 2026, 7:49 PM EDT