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Showing 1–24 of 168 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Working Memory Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction

NCT01056926
View directory record Official record
Conditions
Smoking
Interventions
Quit smoking, Nicotine patch, Placebo Patch
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Sep 5, 2026, 2:34 AM EDT
Enrolling by invitation Not applicable Interventional

Causal Role of Top-Down Theta Oscillations in Prioritization

NCT06252532
View directory record Official record
Conditions
Working Memory, Epilepsy
Interventions
Direct cortical stimulation (DCS) Alpha, Direct cortical stimulation (DCS) Theta, Sham Direct cortical stimulation (DCS), Direct cortical stimulation (DCS) In-Phase Theta, Direct cortical stimulation (DCS) Anti-Phase Theta
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of Chantix on Relapse Prevention for Smoking Cessation

NCT00948649
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Placebo, Varenicline
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2010 · Synced Sep 5, 2026, 2:34 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

TMS for Investigating Memory Facilitation

NCT05462782
View directory record Official record
Conditions
Age-associated Memory Impairment
Interventions
Transcranial Magnetic Stimulation (TMS) Cone Coil, Transcranial Magnetic Stimulation (TMS) Sham Coil
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
60 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Galantamine Effects on Cognitive Function in Marijuana Users

NCT00969696
View directory record Official record
Conditions
Memory
Interventions
Placebo, Galantamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 24, 2012 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Individual Differences in Working Memory Training and Transfer in Older Adults

NCT05396586
View directory record Official record
Conditions
Cognitive Change
Interventions
N-back, Span, Multisensory
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
50 Years to 85 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Irvine, California • Riverside, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 5, 2026, 2:34 AM EDT
Not listed Not applicable Interventional

Efficacy of Pharmacological Treatment of Working Memory Impairment After Traumatic Brain Injury: Evaluation With fMRI

NCT00489892
View directory record Official record
Conditions
Traumatic Brain Injury, Severe Traumatic Brain Injury
Interventions
Modafinil
Drug
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 24, 2007 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Omega-3 and Blueberry Supplementation in Age-Related Cognitive Decline

NCT01746303
View directory record Official record
Conditions
Age-related Memory Disorders, Mood Disorders
Interventions
Omega-3 fatty acid, Blueberry powder, Placebo oil, Placebo powder
Dietary Supplement · Other
Lead sponsor
University of Cincinnati
Other
Eligibility
62 Years to 80 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Sep 5, 2026, 2:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of Memory in Aging

NCT05460468
View directory record Official record
Conditions
Mild Cognitive Impairment, MCI
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 5, 2026, 2:34 AM EDT
Terminated Not applicable Interventional

Effects of Repeated Memory Training on Memory Function and Addiction Related Processes

NCT03285256
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Experimental memory training, Comparator memory training 1, Comparator memory training 2
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Sep 5, 2026, 2:34 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function

NCT04760054
View directory record Official record
Conditions
Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
Interventions
HUBOD, Active Comparator, Control Condition
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Sep 5, 2026, 2:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI

NCT01036711
View directory record Official record
Conditions
Nicotine Dependence, Drug Abuse
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 5, 2026, 2:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Remote Neurocognitive and Psychological Assessment in PKU

NCT04943393
View directory record Official record
Conditions
Phenylketonurias
Interventions
nointervention
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 40 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 5, 2026, 2:34 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Network Control TMS fMRI

NCT05736458
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, Working Memory
Interventions
Transcranial Magnetic Stimulation (TMS), High controllability TMS target
Device · Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 28 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 5, 2026, 2:34 AM EDT
Completed No phase listed Observational

Project TEACH: The Eating, Affect, and Cognitive Health Study

NCT04121598
View directory record Official record
Conditions
Pediatric Obesity, Binge Eating
Interventions
Observational
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 17 Years
Enrollment
48 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Nicotinic Cholinergic System and Cognitive Aging

NCT03408574
View directory record Official record
Conditions
Healthy Aging
Interventions
Nicotine patch, oral mecamylamine, placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Phase 3 Interventional

Effect of Working Memory Training on ADHD Brain Function

NCT02151396
View directory record Official record
Conditions
Attention-Deficit/Hyperactivity Disorder (Combined-subtype)
Interventions
Working memory training, Functional magnetic resonance imaging (fMRI)
Behavioral · Device
Lead sponsor
Hartford Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 29, 2014 · Synced Sep 5, 2026, 2:34 AM EDT
Withdrawn Not applicable Interventional

Effects of Cognitive and Emotional Functioning on Treatment Outcomes

NCT03050632
View directory record Official record
Conditions
Eating Disorders
Interventions
N-back, White Bear Task
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 5, 2026, 2:34 AM EDT
Recruiting Not applicable Interventional

Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD

NCT07219810
View directory record Official record
Conditions
ADHD
Interventions
intermittent theta burst stimulation (iTBS)
Device
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Not applicable Interventional Results available

Neurocognitive Effects of Ziprasidone: Relationship to Working Memory and Dopamine Blockade

NCT00225498
View directory record Official record
Conditions
Schizophrenia
Interventions
ziprasidone vs risperidone or olanzapine
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2015 · Synced Sep 5, 2026, 2:34 AM EDT
Active, not recruiting Phase 2 Interventional

Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury

NCT02849223
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Anodal Transcranial Direct Current Stimulation, Sham stimulation
Device
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 5, 2026, 2:34 AM EDT
Withdrawn Phase 1 Interventional

Efficacy of TDCS for Treating Working Memory Dysfunction and Depression in Temporal Lobe Epilepsy

NCT02268578
View directory record Official record
Conditions
Epilepsy
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 5, 2026, 2:34 AM EDT
Completed Not applicable Interventional

Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease

NCT02857023
View directory record Official record
Conditions
Anemia, Sickle Cell
Interventions
Cogmed RM
Behavioral
Lead sponsor
Steven J. Hardy
Other
Eligibility
7 Years to 16 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 22, 2018 · Synced Sep 5, 2026, 2:34 AM EDT
Recruiting Not applicable Interventional

Understanding Cognitive-Academic Bidirectionality in Math Learning Disabilities

NCT07220746
View directory record Official record
Conditions
Math Learning Disability
Interventions
Coordinated Treatment, Math Treatment
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
6 Years to 8 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 5, 2026, 2:34 AM EDT