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Completed No phase listed Observational Accepts healthy volunteers

Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development

ClinicalTrials.gov ID: NCT01020669

Public ClinicalTrials.gov record NCT01020669. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 8:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development: Supplementary Control Subjects Recruitment

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Background: \- Recent research has suggested that prenatal exposure to drugs may affect specific brain processes, including working memory, stress response, and decision making. However, most of the research on the effects of prenatal drug exposure in humans has been conducted early in life, and very little is known about effects of prenatal drug exposure during the crucial brain development period that takes place during puberty and adolescence. The biological and psychological changes associated with puberty may increase adolescents' sensitivity to prenatal substance exposure. Researchers are interested in using functional magnetic resonance imaging (fMRI) scans to study brain function and learn more about the effects of prenatal drug exposure on adolescents. Objectives: \- To examine the effects of prenatal substance exposure on working memory, decision making, and normal brain activity in adolescents. Eligibility: \- Adolescents between 12 and 17 years of age who are enrolled in a larger follow-up study of children exposed to drugs in utero. Design: * The study will involve a single outpatient session with two fMRI scans that will test working memory and decision-making processes. * Participants will have brief medical history, a physical examination, and a urine test for drugs of abuse. * Participants will then be trained on the working memory and decision-making tasks before having an initial MRI scan to provide a baseline reading. * The fMRI scans will take 40 to 45 minutes each, and participants will have break in between as needed.

Study identification

NCT ID
NCT01020669
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
24 participants

Conditions and interventions

Interventions

Not listed

Eligibility (public fields only)

Age range
13 Years to 17 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 15, 2009
Primary completion
Not listed
Completion
Jul 12, 2011
Last update posted
Jul 1, 2017

2009 – 2011

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
University of Maryland at Baltimore/MPRC Catonsville Maryland 21228

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01020669, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 1, 2017 · Synced Sep 5, 2026

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The complete protocol, eligibility criteria, and contact information for NCT01020669 live on ClinicalTrials.gov.

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