ClinicalTrials.gov record
Completed Phase 3 Interventional

Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer

ClinicalTrials.gov ID: NCT00003592

Public ClinicalTrials.gov record NCT00003592. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 7:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase III Randomized Trial of Methotrexate vs. Paclitaxel in Cisplatin-Ineligible Patients With Advanced Squamous Cell Carcinoma of the Head and Neck

Study identification

NCT ID
NCT00003592
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eastern Cooperative Oncology Group
Network
Enrollment
230 participants

Conditions and interventions

Interventions

  • methotrexate Drug
  • paclitaxel Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 21, 1999
Primary completion
Jul 31, 2000
Completion
Mar 1, 2004
Last update posted
Jun 21, 2023

1999 – 2004

United States locations

U.S. sites
19
U.S. states
11
U.S. cities
16
Facility City State ZIP Site status
Emory University Hospital - Atlanta Atlanta Georgia 30322
Veterans Affairs Medical Center - Atlanta (Decatur) Decatur Georgia 30033
Robert H. Lurie Comprehensive Cancer Center, Northwestern University Chicago Illinois 60611
Veterans Affairs Medical Center - Chicago (Lakeside) Chicago Illinois 60611
CCOP - Illinois Oncology Research Association Peoria Illinois 61602
CCOP - Carle Cancer Center Urbana Illinois 61801
CCOP - Kalamazoo Kalamazoo Michigan 49007-3731
CCOP - Metro-Minnesota Saint Louis Park Minnesota 55416
CCOP - Missouri Valley Cancer Consortium Omaha Nebraska 68131
Veterans Affairs Medical Center - East Orange East Orange New Jersey 07018-1095
University of Rochester Cancer Center Rochester New York 14642
Albert Einstein Comprehensive Cancer Center The Bronx New York 10461
Ireland Cancer Center Cleveland Ohio 44106-5065
CCOP - Toledo Community Hospital Oncology Program Toledo Ohio 43623-3456
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
Veterans Affairs Medical Center - Nashville Nashville Tennessee 37212
Vanderbilt Cancer Center Nashville Tennessee 37232-6838
Medical College of Wisconsin Milwaukee Wisconsin 53226
Veterans Affairs Medical Center - Milwaukee (Zablocki) Milwaukee Wisconsin 53295

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00003592, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 21, 2023 · Synced May 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00003592 live on ClinicalTrials.gov.

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