Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer
Public ClinicalTrials.gov record NCT00017511. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Cevimeline in the Treatment of Xerostomia Secondary to Radiation Therapy for Cancer in the Head and Neck Region
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.
Study identification
- NCT ID
- NCT00017511
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2001 (Type not available)
- Primary completion
- Mar 2003 (Actual)
- Completion
- Mar 2003 (Actual)
- Last update posted
- May 16, 2012
2001 – 2003
United States locations
- U.S. sites
- 71
- U.S. states
- 34
- U.S. cities
- 64
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294-3300 | — |
| Mobile Infirmary Medical Center | Mobile | Alabama | 36607 | — |
| Cranial Pain Research | Tucson | Arizona | 85711 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205-7199 | — |
| Alta Bates Comprehensive Cancer Center | Berkeley | California | 94704 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| Radiation Oncology Center - Sacramento | Sacramento | California | 95816 | — |
| Rebecca and John Moores UCSD Cancer Center | San Diego | California | 92103-8757 | — |
| Stanford University Medical Center | Stanford | California | 94305-5408 | — |
| Colorado Otolaryngology Associates | Colorado Springs | Colorado | 80909 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06360-7106 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Innovative Medical Research of South Florida, Inc. | Miami | Florida | 33138 | — |
| Medical College of Georgia Hospital and Clinics | Augusta | Georgia | 30912 | — |
| Kootenai Medical Center | Coeur d'Alene | Idaho | 83814 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612-7317 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Evanston Northwestern Health Care | Evanston | Illinois | 60201 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7321 | — |
| Central Baptist Hospital | Lexington | Kentucky | 40503 | — |
| James Graham Brown Cancer Center | Louisville | Kentucky | 40202-3267 | — |
| Not listed | Louisville | Kentucky | 40207 | — |
| Tulane Cancer Center | New Orleans | Louisiana | 70112-2699 | — |
| Harbor Hospital Center | Baltimore | Maryland | 21215-1290 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21287-0910 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Ear, Nose, and Throat Specialty Care of Minnesota, P.A. | Minneapolis | Minnesota | 55404 | — |
| University of Minnesota School of Dentistry | Minneapolis | Minnesota | 55455 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| University of Missouri | Columbia | Missouri | 65212 | — |
| Siteman Cancer Center | St Louis | Missouri | 63110-1093 | — |
| University of Nebraska Medical Center | Lincoln | Nebraska | 68583 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-1225 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740-6395 | — |
| Professional Otolaryngology Associates | Voorhees Township | New Jersey | 08043 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| NYU - David B. Kriser Dental Center | New York | New York | 10010-4086 | — |
| Mount Sinai Medical Center, NY | New York | New York | 10029 | — |
| James P. Wilmot Cancer Center | Rochester | New York | 14642 | — |
| State University of New York at Stony Brook School of Medicine | Stony Brook | New York | 11794-8706 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Albert Einstein Clinical Cancer Center | The Bronx | New York | 10461 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Comprehensive Cancer Center at Gaston Memorial | Gastonia | North Carolina | 28053-1747 | — |
| Matthews Radiation Oncology Center | Matthews | North Carolina | 28105 | — |
| Clinical Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Oregon Cancer Institute | Portland | Oregon | 97239 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-1333 | — |
| Head and Neck Associates | Havertown | Pennsylvania | 19083 | — |
| Associated Otolaryngologist | Palmyra | Pennsylvania | 17078 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104-4283 | — |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Eye and Ear Institute | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Memorial Hospital Cancer Center - Chattanooga | Chattanooga | Tennessee | 37404 | — |
| MultiSpecialty Clinical Research | Johnson City | Tennessee | 37601 | — |
| Dial Research Associates, Inc. | Nashville | Tennessee | 37205 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-5671 | — |
| Baylor College of Dentistry | Dallas | Texas | 75246 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Cancer Physicians Associates, PA | Laredo | Texas | 78041 | — |
| Latter Day Saints Hospital | Salt Lake City | Utah | 84143 | — |
| Not listed | McLean | Virginia | 22101 | — |
| Seattle Institute for Biomedical and Clinical Research | Seattle | Washington | 98108 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | — |
| Southwest Washington Medical Center | Vancouver | Washington | 98664 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00017511, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 16, 2012 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00017511 live on ClinicalTrials.gov.