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Terminated Phase 1Phase 2 Interventional

Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

ClinicalTrials.gov ID: NCT01416428

Public ClinicalTrials.gov record NCT01416428. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 9:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 1b/2, Multicenter, Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

Study identification

NCT ID
NCT01416428
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Amgen
Industry
Enrollment
210 participants

Conditions and interventions

Interventions

  • oprozomib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 14, 2011
Primary completion
Aug 7, 2016
Completion
Aug 11, 2019
Last update posted
Nov 7, 2022

2011 – 2019

United States locations

U.S. sites
19
U.S. states
14
U.S. cities
17
Facility City State ZIP Site status
Mayo Clinic Scottsdale Scottsdale Arizona
Pacific Cancer Care Salinas California
Colorado Blood Cancer Institute Denver Colorado
Mayo Clinic Jacksonville Florida
Winship Cancer Institute, Emory University Atlanta Georgia
Rush University Medical Center Chicago Illinois
University of Chicago Medical Center Chicago Illinois
University of Maryland, Greenebaum Cancer Center Baltimore Maryland
Dana Farber Cancer Institute Boston Massachusetts
Mass General Hospital Boston Massachusetts
Virginia Piper Cancer Institute Minneapolis Minnesota
Mayo Clinic Rochester Minnesota
Washington University School of Medicine Division of Oncology St Louis Missouri
John Theurer Cancer Center at Hackensack University Hackensack New Jersey
Hematology Oncology of Northern New Jersey Morristown New Jersey
New York Oncology Hematology Albany New York
Mount Sinai Medical Center New York New York
Sarah Cannon Research Institute / Tennessee Oncology, PLLC Nashville Tennessee
Columbia Basin Hematology and Oncology Kennewick Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01416428, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 7, 2022 · Synced May 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01416428 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →