Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

ClinicalTrials.gov public records Last synced Jun 7, 2026, 4:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
12593
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 1–12 of 12,593 healthy volunteer trials.
Indexed local directory records.

Indexed official records

Conditions
Bilingualism, Late Talkers, Network Science, Vocabulary Acquisition
Interventions
Large Semantic Category Condition, Small Semantic Category Condition
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
24 Months to 30 Months
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Sensory Feedback and Hand Motor Adaptation

NCT07598695
Conditions
Stroke
Interventions
Visual ROM augmentation, Visual ROM reduction
Device
Lead sponsor
The Catholic University of America
Other
Eligibility
20 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Lyme Disease
Interventions
Placebo, TP-05 (lotilaner) High Dose, TP-05 (lotilaner) Low Dose
Drug
Lead sponsor
Tarsus Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
19
States / cities
Pikesville, Maryland • Brookline, Massachusetts • Fall River, Massachusetts + 16 more
Conditions
Down Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Year to 120 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2040
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Moderate Hepatic Impairment
Interventions
Capivasertib
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Rialto, California • San Antonio, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Empowering Vietnamese Americans

NCT07164391
Conditions
Cancer Prevention, HPV Vaccination
Interventions
Digital Intervention for Vietnamese-American Storytelling (VIDAS), Teen General Health
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lansing, Michigan
Recruiting Not applicable Interventional Accepts healthy volunteers

Advancing Biopsychosocial Care Training Initiative

NCT07049861
Conditions
Obesity, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Weight Management
Interventions
Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
5 Years and older
Enrollment
6,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Recruiting Phase 1 Interventional Accepts healthy volunteers

Environment and Alcohol: A Pilot Study

NCT06860607
Conditions
Alcohol Use Disorder
Interventions
Evaluate the effects of Environmental Enrichment (EE) on alcohol consumption
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Adversity, Brain and Opioid Use Study

NCT06355778
Conditions
Healthy, Opioid Use Disorder
Interventions
Computer Tasks, Magnetic Resonance Imaging (MRI)
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Breast Atypical Hyperplasia, Breast Carcinoma, Breast Ductal Carcinoma In Situ, Breast Lobular Carcinoma In Situ
Interventions
Biospecimen Collection, Mammography, Omega-3-Acid Ethyl Esters, Questionnaire Administration, Random Periareolar Fine-Needle Aspiration, Tamoxifen
Procedure · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
45 Years to 74 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Kansas City, Kansas • Ann Arbor, Michigan • Columbus, Ohio
Conditions
Chemoradiation, Esophageal Cancer, Lymphopenia, Pneumococcal Vaccine
Interventions
Pneumonia vaccine
Biological
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

mTBI Identification and Monitoring Through Retinal Scanning

NCT06142435
Conditions
Brain Injuries, Traumatic
Interventions
Head and Intraocular Trauma Tool
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts