Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Public ClinicalTrials.gov record NCT04383210. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CRESTONE: A Phase 2 Study of Seribantumab in Adult Patients With Neuregulin-1 (NRG1) Fusion Positive Locally Advanced or Metastatic Solid Tumors
Study identification
- NCT ID
- NCT04383210
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Elevation Oncology
- Industry
- Enrollment
- 54 participants
Conditions and interventions
Conditions
Interventions
- Seribantumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2020
- Primary completion
- Feb 27, 2024
- Completion
- Feb 27, 2024
- Last update posted
- Apr 2, 2025
2020 – 2024
United States locations
- U.S. sites
- 35
- U.S. states
- 27
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| HonorHealth | Scottsdale | Arizona | 85258 | — |
| Compassionate Care Research Group Inc. | Fountain Valley | California | 92708 | — |
| Pacific Shores Medical Group | Huntington Beach | California | 92648 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California - Irvine Medical Center | Orange | California | 92868 | — |
| University of Colorado Denver | Denver | Colorado | 80220 | — |
| Medical Oncology Hematology Consultants | Newark | Delaware | 19713 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| University Cancer And Blood Center | Athens | Georgia | 30607 | — |
| Hawaii Cancer Care | Honolulu | Hawaii | 96813 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Henry Ford | Detroit | Michigan | 48202 | — |
| Metro Minnesota CCOP | Saint Louis Park | Minnesota | 55416 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Penn State Health Hershey Medical Center Cancer Institute | Hershey | Pennsylvania | 17033 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Sanford Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| The University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Oncology & Hematology Associates of Southwest Virginia Inc., DBA Blue Ridge Cancer Care | Blacksburg | Virginia | 24060 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
| Northwest Medical Specialties, PLLC | Tacoma | Washington | 98405 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04383210, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2025 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04383210 live on ClinicalTrials.gov.