Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies
Public ClinicalTrials.gov record NCT04566393. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT04566393
- Recruitment status
- Available
- Study type
- Expanded access
- Phase
- Not listed
- Lead sponsor
- xCures
- Industry
- Enrollment
- Not listed
Conditions and interventions
Conditions
- BRAF Gene Mutation
- Bladder Cancer
- Cholangiocarcinoma
- Colorectal Cancer
- ERK Mutation
- Esophageal Cancer
- Gastric Cancer
- Glioblastoma
- HRAS Gene Mutation
- Head and Neck Cancer
- Hepatocellular Carcinoma
- KRAS Activating Mutation
- MAPK Gene Mutation
- MEK Mutation
- Melanoma
- NRAS Gene Mutation
- Non Small Cell Lung Cancer
- Ovarian Cancer
- Pancreatic Cancer
- Small Bowel Cancer
- Thyroid Cancer
Interventions
- Ulixertinib (BVD-523) Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jan 27, 2026
United States locations
- U.S. sites
- 27
- U.S. states
- 14
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearview Cancer Institute | Huntsville | Alabama | 35805 | Available |
| Infirmary Cancer Care | Mobile | Alabama | 36604 | Available |
| PCR Oncology | Arroyo Grande | California | 93420 | Available |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | Available |
| xCures Inc. | San Francisco | California | 94105 | Available |
| Providence Saint John's Health Center | Santa Monica | California | 90404 | Available |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | Available |
| Orlando Health | Orlando | Florida | 32806 | Available |
| Mercy Medical Center | Cedar Rapids | Iowa | 52403 | Available |
| Unity Point Health - St. Lukes Hospital | Cedar Rapids | Iowa | 52403 | Available |
| Our Lady of the Lake Hospital | Baton Rouge | Louisiana | 70808 | Available |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | Available |
| Oakland Macomb Cancer Specialists | Sterling Heights | Michigan | 48314 | Available |
| Lake Region Healthcare | Fergus Falls | Minnesota | 56537 | Available |
| Nebraska Hematology Oncology | Lincoln | Nebraska | 68506 | Available |
| Cancer Partners of Nebraska | Lincoln | Nebraska | 68510 | Available |
| Hunterdon Hematology Oncology | Flemington | New Jersey | 08822 | Available |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | Available |
| The Minniti Center for Medical Oncology and Hematology | Mickleton | New Jersey | 08056 | Available |
| Atlantic Health System/Overlook Medical Center | Summit | New Jersey | 07901 | Available |
| Hirschfeld Oncology | Brooklyn | New York | 11206 | Available |
| Stony Brook Cancer Center | Stony Brook | New York | 11794 | Available |
| The Christ Hospital | Cincinnati | Ohio | 45219 | Available |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | Available |
| MD Anderson | Houston | Texas | 77030 | Available |
| UTHealth Houston | Houston | Texas | 77030 | Available |
| UTHealth - Tyler | Tyler | Texas | 75701 | Available |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04566393, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04566393 live on ClinicalTrials.gov.