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Completed Phase 1Phase 2 Interventional

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

ClinicalTrials.gov ID: NCT04666688

Public ClinicalTrials.gov record NCT04666688. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 12:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 as a Single Agent and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemotherapy or Tislelizumab in Patients with Metastatic Solid Tumors

Study identification

NCT ID
NCT04666688
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
PureTech
Industry
Enrollment
44 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 15, 2020 (Actual)
Primary completion
Dec 12, 2024 (Actual)
Completion
Dec 12, 2024 (Actual)
Last update posted
Feb 12, 2025

2020 – 2024

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
UCLA Los Angeles California 90095 —
University of Colorado Hospital Denver Colorado 80045 —
Sarah Cannon Research Institute at Health One Denver Colorado 80218 —
Sarah Cannon Research Institute, Florida Cancer Specialists Sarasota Florida 34232 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
South Texas Accelerated Research Therapeutics Grand Rapids Michigan 49546 —
Columbia University New York New York 10027 —
Memorial Sloan-Kettering Cancer Center New York New York 10065 —
Sarah Cannon Research Institute, Tennessee Oncology Nashville Tennessee 37203 —
University of Texas, M.D. Anderson Cancer Center Houston Texas 77030 —
South Texas Accelerated Research Therapeutics San Antonio Texas 78229 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04666688, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 12, 2025 · Synced Oct 31, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04666688 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →