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Completed Phase 1 Interventional

A Study of CDX-585 in Patients With Advanced Malignancies

ClinicalTrials.gov ID: NCT05788484

Public ClinicalTrials.gov record NCT05788484. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 11:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Dose-escalation and Expansion Study of the PD-1 x ILT4 Bispecific Antibody CDX-585 in Patients With Advanced Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an open-label, non-randomized, multicenter, dose-escalation and expansion study in patients with selected solid tumors.

Study identification

NCT ID
NCT05788484
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Celldex Therapeutics
Industry
Enrollment
20 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 11, 2023 (Actual)
Primary completion
May 21, 2025 (Actual)
Completion
May 21, 2025 (Actual)
Last update posted
Jun 15, 2025

2023 – 2025

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
George Washington University Cancer Center Washington D.C. District of Columbia 20037 —
AdventHealth Celebration Celebration Florida 34747 —
Perlmutter Cancer Center at NYU Langone Health New York New York 10016 —
Providence Cancer Institute Portland Oregon 97213 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05788484, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 15, 2025 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05788484 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →