A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight
Public ClinicalTrials.gov record NCT05929079. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight: A Randomized Double-Blind, Placebo-Controlled Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to is to evaluate the efficacy and safety of retatrutide in participants with type 2 diabetes in participants who have obesity or overweight (J1I-MC-GZBK master protocol) including a subset of participants who have obstructive sleep apnea (OSA) (J1I-MC-GSA2). The study will last about 89 weeks and will include up to 24 visits.
Study identification
- NCT ID
- NCT05929079
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,152 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 10, 2023
- Primary completion
- Jun 15, 2026
- Completion
- Jun 15, 2026
- Last update posted
- Jul 29, 2026
2023 – 2026
United States locations
- U.S. sites
- 40
- U.S. states
- 20
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | 36207 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| Preferred Research Partners | Little Rock | Arkansas | 72211 | — |
| Core Healthcare Group | Cerritos | California | 90703 | — |
| Velocity Clinical Research, Westlake | Los Angeles | California | 90057 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials | Boca Raton | Florida | 33434 | — |
| Teradan Clinical Trials, LLC | Brandon | Florida | 33511 | — |
| Fleming Island Center for Clinical Research | Fleming Island | Florida | 32003 | — |
| Therafirst Medical Center | Fort Lauderdale | Florida | 33308 | — |
| Clinical Site Partners LLC, dba Flourish Research | Miami | Florida | 33186 | — |
| Quantum Clinical Trials | Miami Beach | Florida | 33140 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Clinical Research Center of Florida | Pompano Beach | Florida | 33060 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Clinical Site Partners, LLC dba Flourish Research | Winter Park | Florida | 32789 | — |
| NeuroTrials Research Inc | Atlanta | Georgia | 30328 | — |
| Centricity Research Rincon Pulmonology | Rincon | Georgia | 31406 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Brengle Family Medicine | Indianapolis | Indiana | 46260 | — |
| MedVadis Research Corporation | Waltham | Massachusetts | 02451 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | — |
| Mid Hudson Medical Research | New Windsor | New York | 12553 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Intrepid Research | Cincinnati | Ohio | 45245 | — |
| Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18) | Pittsburgh | Pennsylvania | 15236 | — |
| Preferred Primary Care Physicians | Uniontown | Pennsylvania | 15401 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| Trial Management Associates | Myrtle Beach | South Carolina | 29572 | — |
| Tribe Clinical Research - Spartanburg | Spartanburg | South Carolina | 29301 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05929079, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2026 · Synced Sep 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05929079 live on ClinicalTrials.gov.