A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Public ClinicalTrials.gov record NCT06897475. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Parallel-Group Treatment, Phase 2, Double-Blind Study of Once-Weekly Subcutaneous LY3457263 Compared to Placebo in Participants With Type 2 Diabetes Mellitus on a Stable Dose of Semaglutide or Tirzepatide Who Failed to Achieve HbA1c Goal
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabetes who are not at HbA1c goal when treated with a stable dose of semaglutide or tirzepatide. Participation in the study will last about 9 months.
Study identification
- NCT ID
- NCT06897475
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 27, 2025
- Primary completion
- Nov 30, 2026
- Completion
- Dec 31, 2026
- Last update posted
- Aug 20, 2026
2025 – 2027
United States locations
- U.S. sites
- 25
- U.S. states
- 14
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Helios Clinical Research - Phoenix | Phoenix | Arizona | 85028 | Recruiting |
| Wolverine Clinical Trials | Santa Ana | California | 92706 | Recruiting |
| Renstar Medical Research | Ocala | Florida | 34471 | Recruiting |
| Oviedo Medical Research | Oviedo | Florida | 32765 | Recruiting |
| Balanced Life Health Care Solutions/SKYCRNG | Lawrenceville | Georgia | 30046 | Recruiting |
| Physicians Research Associates | Lawrenceville | Georgia | 30046 | Recruiting |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | Recruiting |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | Recruiting |
| Elite Clinical Trials | Rexburg | Idaho | 83440 | Recruiting |
| Investigators Research Group | Brownsburg | Indiana | 46112 | Recruiting |
| Clinical Research of Philadelphia | Pennington | New Jersey | 08534 | Recruiting |
| NYC Research INC | Long Island City | New York | 11106 | Recruiting |
| Richmond University Medical Center | Staten Island | New York | 10310 | Recruiting |
| Southgate Medical Group | West Seneca | New York | 14224 | Recruiting |
| Lucas Research, Inc. | Morehead City | North Carolina | 28557 | Recruiting |
| Shelby Clinical Research | Shelby | North Carolina | 28150 | Recruiting |
| Providence Health Partners-Center for Clinical Research | Dayton | Ohio | 45439 | Recruiting |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | Recruiting |
| Frontier Clinical Research, LLC | Scottdale | Pennsylvania | 15683 | Recruiting |
| Juno Research | Houston | Texas | 77040 | Recruiting |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | Recruiting |
| Texas Diabetes & Endocrinology, P.A. | Round Rock | Texas | 78681 | Recruiting |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | Recruiting |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | Recruiting |
| Eastside Research Associates | Redmond | Washington | 98052 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06897475, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 20, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06897475 live on ClinicalTrials.gov.