A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes
Public ClinicalTrials.gov record NCT06993792. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Tablet Once Daily Compared With Placebo in Participants With Obesity or Overweight With and Without Type 2 Diabetes
Study identification
- NCT ID
- NCT06993792
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 1,200 participants
Conditions and interventions
Conditions
Interventions
- Orforglipron Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 14, 2025
- Primary completion
- Jul 31, 2027
- Completion
- Jul 31, 2027
- Last update posted
- Apr 23, 2026
2025 – 2027
United States locations
- U.S. sites
- 35
- U.S. states
- 14
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Institute of Arizona (CRI) - Sun City West | Sun City West | Arizona | 85375 | — |
| Novak Clinical Research - Tucson - North La Cholla Boulevard | Tucson | Arizona | 85741 | — |
| Norcal Endocrinology & Internal Medicine | San Ramon | California | 94583 | — |
| Southern California Clinical Research | Santa Ana | California | 92701 | — |
| Care Access - Thousand Oaks | Thousand Oaks | California | 91360 | — |
| Accel Research Sites - DeLand Clinical Research Unit | DeLand | Florida | 32720 | — |
| Innovation Medical Research Center - Fort Lauderdale | Fort Lauderdale | Florida | 33316 | — |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | — |
| Encore Medical Research | Hollywood | Florida | 33024 | — |
| West Orange Endocrinology P.A. | Ocoee | Florida | 34761 | — |
| Care Access - Tampa | Tampa | Florida | 33625 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Accel Research Sites - NeuroStudies Clinical Research Unit | Decatur | Georgia | 30030 | — |
| Care Access - Decatur | Decatur | Georgia | 30030 | — |
| Javara - Privia Medical Group Georgia - Savannah | Savannah | Georgia | 31406 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Care Access - New Iberia | New Iberia | Louisiana | 70560 | — |
| Endocrine and Metabolic Consultants | Rockville | Maryland | 20852 | — |
| Javara - Privia Medical Group - Silver Spring | Silver Spring | Maryland | 20901 | — |
| Great Lakes Research Group, Inc. | Bay City | Michigan | 48706 | — |
| Boeson Research MSO | Missoula | Montana | 59804 | — |
| Javara - Nevada Health Centers - Carson City | Carson City | Nevada | 89706 | — |
| The Machuca Foundation | Las Vegas | Nevada | 89101 | — |
| University of North Carolina Medical Center | Chapel Hill | North Carolina | 27514 | — |
| Javara - Tryon Medical Partners | Charlotte | North Carolina | 28210 | — |
| Care Access - Fayetteville | Fayetteville | North Carolina | 28314 | — |
| The Corvallis Clinic, P.C. | Corvallis | Oregon | 97330 | — |
| Clinical Research of Philadelphia | Philadelphia | Pennsylvania | 19114 | — |
| Frontier Clinical Research, LLC | Smithfield | Pennsylvania | 15478 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Activian Clinical Research | Kingwood | Texas | 77339 | — |
| Texas Valley Clinical Research (TVCR) - Mission | Mission | Texas | 78572 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06993792, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 23, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06993792 live on ClinicalTrials.gov.