A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

ClinicalTrials.gov ID: NCT07020117

Public ClinicalTrials.gov record NCT07020117. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 22, 2026, 11:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NECTINIUM-2: A Phase 1b, 2 Part, Multicenter, Single Arm, Open Label Study to Evaluate the Safety and Efficacy of a Nectin-4 Radiopharmaceutical ([225Ac]Ac-AKY-1189) in Patients With Previously Treated Locally Advanced or Metastatic Solid Tumors

Study identification

NCT ID: NCT07020117
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1
Lead sponsor: Aktis Oncology, Inc.; Industry
Enrollment: 150 participants

Conditions and interventions

Conditions

Interventions

[225Ac]Ac-AKY-1189 (therapeutic) Drug
[64Cu]Cu-AKY-1189 (imaging) Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 21, 2025
Primary completion: Nov 30, 2027
Completion: May 31, 2032
Last update posted: Apr 20, 2026

2025 – 2032

United States locations

U.S. sites: 9
U.S. states: 8
U.S. cities: 9

Facility	City	State	ZIP	Site status
City of Hope	Duarte	California	91010	Recruiting
Hoag Memorial Hospital Presbyterian	Irvine	California	92618	Recruiting
Biogenix Molecular, LLC	Miami	Florida	33165	Recruiting
University of Iowa	Iowa City	Iowa	52242	Recruiting
United Theranostics	Glen Burnie	Maryland	21061	Recruiting
BAMF Health	Grand Rapids	Michigan	49503	Recruiting
Icahn School of Medicine at Mt. Sinai	New York	New York	10029	Recruiting
UPMC	Pittsburgh	Pennsylvania	15232	Recruiting
MD Anderson Cancer Center	Houston	Texas	77030	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07020117, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 20, 2026 · Synced Apr 22, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07020117 live on ClinicalTrials.gov.

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