Condition Directory

Hypertension clinical trials

Directory of U.S. ClinicalTrials.gov public records for Hypertension. Browse Hypertension recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 27, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

529

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How Hypertension studies are organized in the registry

“Hypertension” searches also surface pulmonary hypertension — a different disease with its own research community — so watch for “pulmonary” in titles when scanning results. The blood-pressure portfolio itself includes a high share of behavioral, dietary, and device studies alongside medication trials.

Terms that often appear in related listings

blood pressure resistant hypertension pulmonary hypertension renal denervation

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 253–264 of 529 matching trials for Hypertension.

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Conditions: Blood Pressure Measurement in Pregnancy, Hypertension Disorders in Pregnancy, Inspiratory Strength Training (IST), Pregnancy
Interventions: Exercise at 15% PI max, Exercise at 50% PI max; Other
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Heart Failure With Preserved Ejection Fraction, Pulmonary Hypertension
Interventions: Placebo, TX000045- Dose A, TX000045- Dose B; Drug
Lead sponsor: Tectonic Therapeutic; Industry
Eligibility: 18 Years to 83 Years
Enrollment: 191 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 25
States / cities: Phoenix, Arizona • Scottsdale, Arizona • San Francisco, California + 21 more

Conditions: Ascites, Hypertension, Portal
Interventions: Gore® Viatorr® Endoprosthesis with controlled expansion, Large Volume Paracentesis with albumin infusion; Device · Procedure
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Essential (Primary) Hypertension, Hypertension
Interventions: Mindfulness in Motion; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Ocular Hypertension, Suspect Glaucoma
Interventions: Latanoprost (0.005%), Rocklatan (Netarsudil 0.02%/ latanoprost 0.005); Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 4
States / cities: Baltimore, Maryland • Columbia, Maryland • Silver Spring, Maryland

Conditions: Hypertension, Hypertension Complicated With Type 2 Diabetes
Interventions: Active comparator, iTHRIVE intervention; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Baltimore, Maryland • Gaithersburg, Maryland

Conditions: Hypertension
Interventions: Community Mobilization; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 85 Years
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • New York, New York

Conditions: Blood Pressure, High, Hypertension, Hypertension (HTN)
Interventions: Not listed
Lead sponsor: Vivek Bhalla; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Palo Alto, California • Durham, North Carolina

Conditions: Diet, Healthy, Gestational Diabetes, Gestational Hypertension, Gestational Weight Gain, Pregnancy Complications
Interventions: Delivering HOPE, Enhanced Standard of Care (ESoC); Behavioral
Lead sponsor: University of Arkansas; Other
Eligibility: 16 Years to 44 Years · Female only
Enrollment: 1,440 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 8
States / cities: Corning, Arkansas • Lavaca, Arkansas • Marianna, Arkansas + 5 more

Conditions: Hypertension
Interventions: Precision Nudging for Hypertension Management; Behavioral
Lead sponsor: Lirio; Industry
Eligibility: 18 Years and older
Enrollment: 12,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Greensboro, North Carolina

Conditions: Chronic Kidney Disease and Hypertension
Interventions: Baxdrostat/dapagliflozin, Dapagliflozin in combination with placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years and older
Enrollment: 2,554 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 114
States / cities: Fairhope, Alabama • Phoenix, Arizona • Surprise, Arizona + 97 more

Conditions: Interstitial Lung Disease, Pulmonary Hypertension
Interventions: LIQ861; Drug
Lead sponsor: Liquidia Technologies, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 23
States / cities: Phoenix, Arizona • Fresno, California • La Jolla, California + 20 more

About this Hypertension clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Hypertension as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Hypertension.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Hypertension clinical trials

How Hypertension studies are organized in the registry

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Stored official records

Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy

A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents

Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension

Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects

Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure

Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention

IMPACT-HTN Study of Patients With Hypertension

Delivering HOPE (Helping Women Optimize Prenatal Equity)

Precision Nudging for Hypertension Management: Observational Study

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH

About this Hypertension clinical trials directory page