Condition Directory

Hypertension clinical trials

Directory of U.S. ClinicalTrials.gov public records for Hypertension. Browse Hypertension recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 19, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 19, 2026, 7:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

530

Shown on this page

Current sort

How Hypertension studies are organized in the registry

“Hypertension” searches also surface pulmonary hypertension — a different disease with its own research community — so watch for “pulmonary” in titles when scanning results. The blood-pressure portfolio itself includes a high share of behavioral, dietary, and device studies alongside medication trials.

Terms that often appear in related listings

blood pressure resistant hypertension pulmonary hypertension renal denervation

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 313–324 of 530 matching trials for Hypertension.

Indexed local directory records.

Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Stored official records

Open in full search

Conditions: Diabetes Mellitus, Hypertension
Interventions: AUDIO, NOTES; Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 1,022 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Manchester, New Hampshire • Nashville, Tennessee • Galveston, Texas

Conditions: Ocular Hypertension Glaucoma, POAG
Interventions: DSLT; Device
Lead sponsor: The New York Eye Surgery Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Chronic Obstructive Pulmonary Disease, Dyspnea, Pulmonary Hypertension
Interventions: Placebo, Tadalafil; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 35 Years to 89 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 5
States / cities: Aurora, Colorado • Decatur, Georgia • Boston, Massachusetts + 2 more

Conditions: Hypertension (HTN), Nutritional Deficiency Related Cardiovascular Risk in Athletes, Vascular Stiffness
Interventions: Not listed
Lead sponsor: North Carolina Agriculture & Technical State University; Other
Eligibility: 18 Years to 26 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Greensboro, North Carolina

Conditions: Diabetes, Hypertension, Overweight and Obesity, Pre-diabetes
Interventions: Multi-level, community-digital health promotion intervention; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 664 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Baltimore, Maryland

Conditions: COPD, Exercise, Exercise Training, Pulmonary Hypertension, Right Ventricular (RV) Dysfunction
Interventions: Exercise training; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 40 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: COPD, Exercise, Exercise Training, Pulmonary Hypertension, Right Ventricular Dysfunction
Interventions: Exercise; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 40 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Hypertension
Interventions: mGlide; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 85 Years
Enrollment: 395 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Ocular Hypertension (OHT), Open-angle Glaucoma (OAG)
Interventions: Direct Selective laser Trabeculoplasty; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Uncontrolled Hypertension
Interventions: Community Health Worker (CHW) assistance, Medically-tailored Meals (MTM), Resource information; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Contextual Drivers of Health, Diabetes Mellitus, Type 2, Hypertension, Non-medical Health-related Needs, Primary Care, Social Determinants of Health
Interventions: Implementation Support; Other
Lead sponsor: OCHIN, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Asthma, COPD, Cystic Fibrosis, Interstitial Lung Disease, Other Lung Disease, Pulmonary Hypertension, Pulmonary Infection
Interventions: Hyperpolarized Xe129; Drug
Lead sponsor: Mario Castro, MD, MPH; Other
Eligibility: 3 Years and older
Enrollment: 260 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Kansas City, Kansas

About this Hypertension clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Hypertension as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Hypertension.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Hypertension clinical trials

How Hypertension studies are organized in the registry

Filter and sort this condition

Stored official records

Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

Direct Selective Laser Trabeculoplasty (DSLT) for Patients With Glaucoma or Ocular Hypertension Previously Treated With SLT

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

Low Energy Availability and Hypertension in Division I HBCU Athletes

Community Engagement Alliance Against Disparities

Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease

Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

mGlide RCT: A Clinical Glide Path To Close the Guideline-to-Practice Gap In HTN Management

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity

DEDICATE: aDvancing carE Management aDoption In Community heAlTh cEnters

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

About this Hypertension clinical trials directory page