Condition Directory

Hypertension clinical trials

Directory of U.S. ClinicalTrials.gov public records for Hypertension. Browse Hypertension recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 18, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 18, 2026, 7:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

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How Hypertension studies are organized in the registry

“Hypertension” searches also surface pulmonary hypertension — a different disease with its own research community — so watch for “pulmonary” in titles when scanning results. The blood-pressure portfolio itself includes a high share of behavioral, dietary, and device studies alongside medication trials.

Terms that often appear in related listings

blood pressure resistant hypertension pulmonary hypertension renal denervation

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 373–384 of 530 matching trials for Hypertension.

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Conditions: Adult Congenital Heart Disease, Connective Tissue Disease, Other Cardiovascular Conditions, Pulmonary Hypertension
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 16 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2050
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Pulmonary Hypertension
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Habits, Hypertension, Medication Adherence
Interventions: Action Planning, Wellth + Cue, Wellth App; Behavioral
Lead sponsor: Chad Stecher@asu.edu; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Multiple System Atrophy, Orthostatic Hypotension, Supine Hypertension
Interventions: Placebo, Trimethaphan; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hyperlipidemias, Hypertension
Interventions: Penn Med Healthy Heart Program; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 35 Years to 80 Years
Enrollment: 1,980 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cardiometabolic Diseases, Hypertension (HTN)
Interventions: High Salt Diet, Low Salt Diet, Saline Infusion; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Healthy Individuals With no Cardiopulmonary Disease, Heritable Pulmonary Arterial Hypertension, Idiopathic Pulmonary Arterial Hypertension, Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo
Interventions: Not listed
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 15 Years to 80 Years
Enrollment: 150 participants
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Alzheimer Disease (AD), Cardio Vascular Disease, Disability Physical, Frailty Syndrome, Healthy Aging, Hypertension, Metabolic Syndrome (MetS), Mild Cognitive Impairment (MCI), Obesity &Amp; Overweight
Interventions: Not listed
Lead sponsor: Marymount University; Other
Eligibility: 50 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Arlington, Virginia

Conditions: Diabetes, High Risk Pregnancy, Hypertension, Remote Patient Monitoring
Interventions: Fetal ECG monitoring; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Glaucoma, Glaucoma Suspect, Ocular Hypertension, Open-Angle Glaucoma
Interventions: Durysta, Bimatoprost Intracameral Implant 10 µg; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Left Heart Disease, Pulmonary Hypertension, Pulmonary Vascular Disease
Interventions: Lung ultrasound, Transthoracic Echocardiography (TTE); Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cardiovascular Complication, Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia
Interventions: Dapagliflozin 10mg Tab, Placebo; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

About this Hypertension clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Hypertension as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Hypertension.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Hypertension clinical trials

How Hypertension studies are organized in the registry

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Stored official records

Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders

Trans-pulmonary Biomarkers in Pulmonary Hypertension

Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication

Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic

Penn Medicine Healthy Heart

Genetic Architecture of Natriuretic Peptides and Blood Pressure Response

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

Remote Fetal Monitoring in High Risk Pregnancies

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

Pulmonary Hypertension in Left Heart Disease

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

About this Hypertension clinical trials directory page