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Mild Cognitive Impairment clinical trials

Directory of U.S. ClinicalTrials.gov public records for Mild Cognitive Impairment. Browse Mild Cognitive Impairment recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced November 5, 2026 Report an issue

ClinicalTrials.gov public records Last synced Nov 4, 2026, 7:23 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
845
Shown on this page
12
Current sort
Recently updated
Condition scope
Mild Cognitive Impairment
Additional filters apply within this condition.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

How Mild Cognitive Impairment studies are organized in the registry

MCI is the registry’s main gateway term for early-stage memory and Alzheimer’s-prevention research; “amnestic MCI” labels the memory-specific subset. The portfolio includes a high share of observational cohort studies from memory clinics, so the study-type filter cleanly separates those from interventional trials.

Terms that often appear in related listings

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

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These controls apply only within Mild Cognitive Impairment. Default order is Recently updated. Add location, sponsor, treatment, or recruitment status to narrow this condition page further.

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Showing 493–504 of 845 matching trials for Mild Cognitive Impairment.
Live ClinicalTrials.gov results.
Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Live official records

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Completed Not applicable Interventional Results available

Exercise Training to Improve Cognitive Function

NCT03824639
Conditions
Mild Cognitive Impairment
Interventions
Structured exercise, Health Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Mild Cognitive Impairment, Alzheimer's Disease
Interventions
Memory Training, Kundalini yoga and meditation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 90 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Dementia, Mild Cognitive Impairment, Alzheimer Disease, Lewy Body Disease, Frontotemporal Dementia, Vascular Dementia
Interventions
Stories in the Moment Dance Program - Online
Other
Lead sponsor
DanceStream Projects
Other
Eligibility
50 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Not listed No phase listed Observational Accepts healthy volunteers

The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over

NCT06011681
Conditions
Depression, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Miro Health
Other
Eligibility
60 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sacramento, California • Miami, Florida
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Power Life Sciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Conditions
Mild Cognitive Impairment
Interventions
11C-acetate
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

5-Cog Battery for Detecting Cognitive Impairment and Dementia

NCT03816644
Conditions
Dementia, Cognitive Impairment, Mild Cognitive Impairment, Neurocognitive Disorders
Interventions
5-Cog, Health Literacy & Grip Assessment
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
65 Years and older
Enrollment
1,201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Alzheimer Disease
Interventions
Routine Care Documentation
Other
Lead sponsor
Alzheimer's Disease and Related Disorders Association, Inc
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational

DHS MIND Metabolomics

NCT03975309
Conditions
Diabetes
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

Cognitive Screening Made Easy for PCPs

NCT05082883
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
Interventions
Risk Assessment Cognitive Screening
Diagnostic Test
Lead sponsor
University of Texas at Austin
Other
Eligibility
60 Years and older
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional

Dual-task Training for Function in MCI

NCT04059705
Conditions
Mild Cognitive Impairment
Interventions
Dual-Task Training
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Buffalo, New York
Completed Not applicable Interventional Results available

Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment

NCT02155946
Conditions
Mild Cognitive Impairment, Alzheimer's Disease
Interventions
Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 88 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan

About this Mild Cognitive Impairment clinical trials directory page

What this page lists
U.S. ClinicalTrials.gov public records that list Mild Cognitive Impairment as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results
Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Mild Cognitive Impairment.
Where the data comes from
Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Related: all condition pages, browse by drug or therapy, browse by U.S. city, browse by sponsor, or open the full search for Mild Cognitive Impairment.