Condition Directory

Obesity clinical trials

Directory of U.S. ClinicalTrials.gov public records for Obesity. Browse Obesity recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 30, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 30, 2026, 1:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

6025

Shown on this page

Current sort

How Obesity studies are organized in the registry

Obesity research spreads across several neighboring registry terms — “overweight,” “weight loss,” and “metabolic syndrome” all label closely related studies — so checking more than one term gives a fuller picture. The portfolio includes many behavioral and lifestyle studies alongside drug trials, which makes the study-type filter (interventional vs. observational) more informative than usual.

Terms that often appear in related listings

weight loss overweight metabolic syndrome bariatric

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 265–276 of 6,025 matching trials for Obesity.

Live ClinicalTrials.gov results.

Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Live official records

Open in full search

Conditions: Obesity
Interventions: Hypertonic saline infusion, Water deprivation; Other
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Endometrial Cancer, Obesity
Interventions: Tirzepatide; Drug
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Obese, Healthy, Bariatric Surgery Candidate
Interventions: Endoscopic biopsy; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Obesity
Interventions: Fun First, Weight Watchers; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Enrollment: 321 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Overweight and Obesity
Interventions: Synbiotic Group, Placebo Group; Dietary Supplement · Other
Lead sponsor: Texas Christian University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Obesity
Interventions: Exercise Intervention, Nutritional Intervention; Behavioral
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: 12 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Little Rock, Arkansas

Conditions: Genetics, Obesity
Interventions: Diet modification; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 20 Years to 45 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sleep Apnea, PreDiabetes, Overweight or Obesity
Interventions: Diet and exercise coaching, CPAP Treatment; Behavioral · Other
Lead sponsor: University of Chicago; Other
Eligibility: 20 Years to 65 Years
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Endometrial Atypical Hyperplasia, Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Cancer Stage I, Endometrial Cancer, Fertility-Sparing Treatment (FST), Obesity & Overweight
Interventions: Semaglutide (Wegovy) weekly injection, LNG-IUD (Progestin), Structured Weight Loss Program; Drug · Device · Behavioral
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 4
States / cities: Houston, Texas

Conditions: Obesity
Interventions: Ask-Advise-Connect (AAC), Text Messaging (TM), Connect Only (CO), TM-Continued (TM-Cont), Continued TM plus Motivation And Problem Solving (TM+MAPS); Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 5,354 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Obesity
Interventions: WISE (We Inspire Smart Eating); Behavioral
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Pediatric Obesity, Nutrition Disorders, Binge Eating, Body Weight
Interventions: Restricted access task, Structured Intake; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 8 Years to 11 Years
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Buffalo, New York

About this Obesity clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Obesity as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Obesity.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Obesity clinical trials

How Obesity studies are organized in the registry

Filter and sort this condition

Live official records

Water Deprivation Protocol

Tirzepatide in Obesity-Driven Endometrial Cancer

Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome

Stanford Healthy Heart Study

Next-Generation Synbiotic in Individuals With Overweight or Obesity

Level Up! (The Combined and Independent Effects of Exercise Training and Dietary Enhancement on Cardiometabolic Health in Adolescents With Obesity)

Inherited and Environmental Risks Acting on Body Weight

Technology-Supported Treatment of Sleep Apnea in Prediabetes

Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical Hyperplasia and Grade 1 Endometrial Cancer

Partnership to Reduce Obesity in Community Health Center Patients (SMARTLife Utah)

Developing and Testing Implementation Strategies for Evidence-Based Obesity Prevention in Childcare

The Intersection Between Loss of Control Eating and Obesity: The Role of Restriction and Food Reinforcement

About this Obesity clinical trials directory page