Condition Directory

Obesity clinical trials

Directory of U.S. ClinicalTrials.gov public records for Obesity. Browse Obesity recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced November 3, 2026 Report an issue

ClinicalTrials.gov public records Last synced Nov 2, 2026, 7:45 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

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How Obesity studies are organized in the registry

Obesity research spreads across several neighboring registry terms — “overweight,” “weight loss,” and “metabolic syndrome” all label closely related studies — so checking more than one term gives a fuller picture. The portfolio includes many behavioral and lifestyle studies alongside drug trials, which makes the study-type filter (interventional vs. observational) more informative than usual.

Terms that often appear in related listings

weight loss overweight metabolic syndrome bariatric

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 889–900 of 6,028 matching trials for Obesity.

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Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Live official records

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Conditions: Obesity
Interventions: Incretin-based therapies (GLP-1 and GLP-1/GIP); Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 125,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Obesity, Child
Interventions: Building Healthy Families Program; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 5 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Physical Activity, Childhood Obesity
Interventions: Treatment, Health Education; Behavioral · Other
Lead sponsor: University of South Carolina; Other
Eligibility: 11 Years to 16 Years
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Columbia, South Carolina • Sumter, South Carolina

Conditions: Child Overnutrition, Child Obesity, Child Nutrition Disorders
Interventions: Eatable Alphabet, Usual Care; Behavioral
Lead sponsor: Northwell Health; Other
Eligibility: 2 Years to 10 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Obese
Interventions: Not listed
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2025
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Childhood Obesity, Obesity
Interventions: Prevention Plus; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 4 Years to 10 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Knoxville, Tennessee

Conditions: Obesity
Interventions: MBX 4291, Placebo; Drug
Lead sponsor: MBX Biosciences; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: Doral, Florida • Lexington, Kentucky • Kansas City, Missouri + 1 more

Conditions: Obesity
Interventions: Increase Fruits and Vegetables, Decrease Snack Foods, Increase Fruits and Vegetables and Decrease Snack Foods; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 6 Years to 12 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2025
U.S. locations: 2
States / cities: Knoxville, Tennessee

Conditions: Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions: Culturally-tailored, enhanced adaption of Diabetes Prevention Program; Behavioral
Lead sponsor: University of Missouri, Kansas City; Other
Eligibility: 18 Years and older
Enrollment: 408 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Overweight and Obesity
Interventions: Core Behavioral Weight Loss (BWL) intervention, Dyadic Action Planning, Joint Feedback, Autonomy Support Training, Home Environment Modifications; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 75 Years
Enrollment: 762 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Obesity
Interventions: Low-ED, Energy Balance; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years to 70 Years
Enrollment: 345 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Obesity, Women (Between 30 to 60 Years Old)
Interventions: Protein Rich Foods; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 30 Years to 60 Years · Female only
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Austin, Texas

About this Obesity clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Obesity as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Obesity.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Obesity clinical trials

How Obesity studies are organized in the registry

Filter and sort this condition

Live official records

Estimating the Impact of Obesity Medications on Clinical and Economic Outcomes

Scaling up Building Healthy Families

The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)

Eatable Alphabet as a Nutrition Education Tool

Influence of Changes in Food Group Variety on Food Cravings, Energy Intake, and Weight Loss After Bariatric Surgery

EBT Fruit and Vegetable Prescription

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

The Effect of Three Different Dietary Messages on Dietary Intake and Health in Families

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

Becoming United in Lifestyle Decisions

Eat Well for Life: A Weight Loss Maintenance Study

Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity)

About this Obesity clinical trials directory page