Condition Directory

Parkinson's Disease clinical trials

Directory of U.S. ClinicalTrials.gov public records for Parkinson's Disease. Browse Parkinson's Disease recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 15, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 15, 2026, 11:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

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How Parkinson's Disease studies are organized in the registry

Records generally use the registry spelling “Parkinson disease.” The portfolio mixes drug studies with a high share of device, exercise, and rehabilitation research, so the study-type filter is unusually useful here. Disease-stage language (“early,” “advanced,” “levodopa-treated”) commonly appears in titles.

Terms that often appear in related listings

early Parkinson deep brain stimulation levodopa gait

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 169–180 of 280 matching trials for Parkinson's Disease.

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Conditions: Parkinson Disease
Interventions: Auditory Cueing, Visual Cueing, tactile Cueing; Other
Lead sponsor: Northumbria University; Other
Eligibility: 50 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Parkinson Disease, Parkinson
Interventions: Medtronic RC+S DBS system; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 45 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Parkinson's Disease
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 50 Years to 99 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Parkinson Disease
Interventions: Dental Mouthpiece; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 30 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Parkinson Disease
Interventions: Not listed
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 40 Years to 100 Years
Enrollment: 439 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Parkinson's Disease
Interventions: Varenicline, Placebo; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 45 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Dyskinesias, Parkinson Disease, Movement Disorders, Parkinsonian Disorders, Anti-Dyskinesia Agents
Interventions: AFQ056, Placebo; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 30 Years to 80 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 5
States / cities: Sunnyvale, California • Englewood, Colorado • Tampa, Florida + 2 more

Conditions: Dyskinesias, Parkinson Disease, Movement Disorders, Parkinsonian Disorders, Anti-Dyskinesia Agents
Interventions: AFQ056; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: Not listed
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 3
States / cities: Englewood, Colorado • Kansas City, Kansas • Milwaukee, Wisconsin

Conditions: Parkinson's Disease
Interventions: Vercise DBS settings; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Valencia, California

Conditions: Parkinson's Disease
Interventions: Deep Brain Stimulation (DBS) at 60 Hz, Deep Brain Stimulation (DBS) at 130 Hz, Deep Brain Stimulation (DBS) Off (Sham); Device
Lead sponsor: University of Chicago; Other
Eligibility: 45 Years to 75 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parkinson's Disease
Interventions: Cycling at Forced rate, Cycling at self-selected rate; Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 30 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parkinson Disease, Mild Cognitive Impairment
Interventions: High Intensity Endurance Exercise; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 40 Years to 85 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

About this Parkinson's Disease clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Parkinson's Disease as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Parkinson's Disease.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Parkinson's Disease clinical trials

How Parkinson's Disease studies are organized in the registry

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Live official records

Brain Activity During Gait in Parkinson's

State-dependent Pathophysiological Oscillations in Parkinson's Disease and Treatment With DBS Using the Medtronic RC+S

Cholinergic Mechanisms of Gait Dysfunction in Parkinson's Disease

Dental Appliance for Parkinson's Disease

Perception, Cognition, and Gait in Parkinson's Disease

Crossover Target Engagement Study of Cholinergic Mechanisms of Gait Dysfunction in Parkinson's Disease (Project #3 - Experiment 3 [UdallP3E3])

Evaluation of the Efficacy and Safety of Modified Release AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

CUSTOM-DBS: Current Steering to Optimize Deep Brain Stimulation

Long-term Effect of Low Frequency Stimulation on Aspiration and Freezing of Gait in PD With STN DBS

Cycling in Parkinson's Disease

Mild Cognitive Impairment and Endurance Exercise in Parkinson's Disease

About this Parkinson's Disease clinical trials directory page