Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

The live registry is temporarily unavailable. These stored records may be incomplete or out of date. Check the official record for current status and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 3:39 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5003
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 1477–1488 of 5,003 healthy volunteer trials.
Indexed local directory records.

Stored official records

Conditions
Chin Augmentation
Interventions
Restylane Lyft with Lidocaine
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
8
States / cities
Westport, Connecticut • Boynton Beach, Florida • Coral Gables, Florida + 4 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Adaptive Recruitment Curve Analysis Using Bayesian Modeling

NCT07561372
Conditions
Modeling of Recruitment Curves
Interventions
Algorithm: Uniform Sampling, Algorithm: hbMEP-adaptive algorithm (version 1), Algorithm: hbMEP-adaptive algorithm (version 2), Digitimer DS8R Transcutaneous Electrical stimulation, ML-PEST, MagPro X100 Transcranial Magnetic Stimulation
Other · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Motorized Prostheses for Lower-limb Amputees

NCT07486063
Conditions
Lower-Limb Amputation
Interventions
Powered and passive lower limb prosthesis and control
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2032
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Exercise-Induced Vocal Cord Dysfunction, Paradoxical Vocal Fold Motion, Vocal Cord Dysfunction
Interventions
Carbon Dioxide, Mechano-acoustic device
Drug · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 26 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
HIV
Interventions
Philadelphia TelePrEP Program Direct-to-Consumer Model, STEP-UP
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Aphasia
Interventions
Aphasia identification (ID) card
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years to 59 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Springfield, Massachusetts
Conditions
Portal Hypertension
Interventions
Electronic Health Record Review, Liver Biopsy, Medical Device Usage and Evaluation, Perflutren Lipid Microspheres, Ultrasound Imaging
Other · Procedure · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Recruiting No phase listed Observational Accepts healthy volunteers

Social Disconnection Study

NCT06705348
Conditions
Social Disconnection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
55 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Incontinence, Prolapse
Interventions
Telehealth intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Recruiting No phase listed Observational Accepts healthy volunteers

Endogenous Pain Inhibition Deficiency in Chronic TMD Pain

NCT06617494
Conditions
Chronic Temporomandibular Disorders (TMD)
Interventions
Pain modulation testing
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Recruiting Not applicable Interventional Accepts healthy volunteers

FAMILY Sleep Program

NCT06571305
Conditions
Cancer
Interventions
Brief Behavioral Treatment for Insomnia (BBTI), My Sleep Our Sleep (MSOS)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Recruiting No phase listed Observational Accepts healthy volunteers

Using Consumer-grade Wearable Devices for Fall Risk Evaluation and Alerts

NCT06508892
Conditions
Mass Screening
Interventions
risk of fall
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Flint, Michigan