Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 3, 2026, 9:58 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
4977
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 1645–1656 of 4,977 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Recruiting No phase listed Observational Accepts healthy volunteers

Shield Post-Approval Study Protocol

NCT06880055
Conditions
Colo-rectal Cancer
Interventions
Shield Blood Test for colo-rectal cancer Screening
Diagnostic Test
Lead sponsor
Guardant Health, Inc.
Industry
Eligibility
45 Years to 81 Years
Enrollment
3,375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
60
States / cities
Chandler, Arizona • Gilbert, Arizona • Anaheim, California + 52 more
Conditions
COVID-19 Vaccines
Interventions
BNT162b2 Vaccine, Tdap Vaccine
Biological
Lead sponsor
BioNTech SE
Industry
Eligibility
18 Years to 64 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
5
States / cities
Walnut Creek, California • Miami Lakes, Florida • Honolulu, Hawaii + 2 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Multi-Site Feasibility Testing a Meditation App for Youth in the Legal System

NCT07674303
Conditions
Behavioral Health
Interventions
Bodhi AIM, HIB
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
13 Years to 20 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Phase 2 Interventional Accepts healthy volunteers

Cannabis for Obesity Trial

NCT06137365
Conditions
Obesity
Interventions
Cannabis, Placebo
Drug
Lead sponsor
Joshua A. Lile, Ph.D.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Bioavailability of Broccoli Extract Supplements

NCT07564674
Conditions
Diet, Healthy
Interventions
Avmacol Extra Strength with coating - 1 tablet, Avmacol chewable wafer - 2 tablets, Avmacol Extra Strength with coating - 2 tablets
Dietary Supplement
Lead sponsor
Oregon State University
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Corvallis, Oregon
Conditions
Neurodegenerative Diseases, Parkinson Disease, Parkinson Disease Psychosis
Interventions
Pimavanserin
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
50 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Recruiting No phase listed Observational Accepts healthy volunteers

Intalight Reference Database Protocol for VG200D

NCT07751484
Conditions
The Focus of This Study is to Collect OCT Data on Normal Eyes
Interventions
OCT device called VG200D
Device
Lead sponsor
Intalight, Inc
Industry
Eligibility
22 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
3
States / cities
San Diego, California • Chicago, Illinois • Bloomington, Indiana
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Structured Communicative Interaction, Clear Speech, Unstructured communicative interaction, Clear Speech Structured Communicative Interaction
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 90 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Omega-3 Deficiency, DHA and EPA Blood Levels, Cardiovascular Health, Cognitive Health
Interventions
Omega Active Supplement
Dietary Supplement
Lead sponsor
Revive Active
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Recruiting Not applicable Interventional Accepts healthy volunteers

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

NCT06476795
Conditions
Cardiovascular Diseases, Adiposity, Cardiometabolic Syndrome
Interventions
Chardonnay Marc
Other
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Davis, California
Conditions
Cervical Cancer Screening Methods
Interventions
Participant Choice of HPV Self-Test, Survey: Participant cancer history and cervical cancer prevention/screening knowledge, Participant Choice of Standard of Care in-clinic Pap-test
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Neoplasms, Healthy
Interventions
LY4214835
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
6
States / cities
New Haven, Connecticut • Boston, Massachusetts • Charlestown, Massachusetts + 3 more