Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 4, 2026, 7:59 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
4977
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Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
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ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 1693–1704 of 4,977 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Recruiting Not applicable Interventional Accepts healthy volunteers

Robotic OCT for ER Anterior Eye Exams

NCT06566339
Conditions
Develop and Test Robotically Assisted Imaging System for the Front of the Eye
Interventions
Robotically Aligned Eye Imaging System
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Cardiac Health of Adults With Trauma

NCT05700201
Conditions
Posttraumatic Stress Disorder
Interventions
Lifestyle / Healthy Behavior Intervention, standard care
Behavioral · Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Conditions
Localized Renal Pelvis and Ureter Urothelial Carcinoma, Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Soft Tissues, Metastatic Renal Pelvis and Ureter Urothelial Carcinoma, Recurrent Bladder Carcinoma, Recurrent Prostate Carcinoma, Recurrent Renal Pelvis and Ureter Urothelial Carcinoma, Stage IV Bladder Cancer AJCC v7, Stage IV Bladder Urothelial Carcinoma AJCC v7, Stage IV Prostate Cancer AJCC v7
Interventions
Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Male only
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Lung Cancer Screening
Interventions
Sybil Artificial Intelligence (AI) screening
Diagnostic Test
Lead sponsor
University of Illinois Chicago
Other
Eligibility
50 Years to 80 Years
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2038
U.S. locations
2
States / cities
Chicago, Illinois
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Chronic Lung Allograft Dysfunction MRI Study

NCT06406777
Conditions
Chronic Lung Allograft Dysfunction Lung MRI (CLAD)
Interventions
Spirometry, Contrast Lung Computed Tomography (CT) Scan, Oxygen enhanced magnetic resonance imaging (OE-MRI) Scan, 129Xe MRI scans
Diagnostic Test · Drug
Lead sponsor
Sean Fain
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Postoperative Physical Functioning
Interventions
Pelvic floor Home Exercise Program, this intervention is comprised of specific exercises that are easy to complete at home
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurobehavioral Changes Following Spaceflight Stressors

NCT07293494
Conditions
Stressor, Individual, Alcohol Impairment, Sleep Deprivation, Impairment, Cognitive
Interventions
Alcohol Administration, Sleep Deprivation, Control
Other · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

18F-FTHA IMAGING OF THE INTESTINAL AND CENTRAL LYMPHATIC SYSTEM

NCT07645573
Conditions
Lymphatic Obstruction
Interventions
[18F]FTHA PET/CT scan
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Thrive With Type 1 Diabetes 2026

NCT07522866
Conditions
Type1diabetes
Interventions
TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm
Behavioral
Lead sponsor
Emory University
Other
Eligibility
31 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia
Recruiting No phase listed Observational Accepts healthy volunteers

Pneumococcal Carriage Duration

NCT07748832
Conditions
Pneumococcal Carriage
Interventions
Oropharyngeal (OP) swab
Other
Lead sponsor
University of Central Florida
Other
Eligibility
28 Days to 48 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Cervical Cancer Screening Methods
Interventions
Participant Choice of HPV Self-Test, Survey: Participant cancer history and cervical cancer prevention/screening knowledge, Participant Choice of Standard of Care in-clinic Pap-test
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Bringing Medicines for HIV Prevention to a Family Planning Clinic

NCT06930508
Conditions
HIV, PrEP
Interventions
Patient participant screening, Physician participant training
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
16 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Providence, Rhode Island