Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

The live registry is temporarily unavailable. These stored records may be incomplete or out of date. Check the official record for current status and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:48 AM EDT

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
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Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
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ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 1765–1776 of 4,982 healthy volunteer trials.
Indexed local directory records.

Stored official records

Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Sleep on Human Microbiota: Implications for Health and Disease

NCT02573753
Conditions
Sleep
Interventions
Sleep restriction, Weight gain
Behavioral · Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Binocular Visual Function, Mild Traumatic Brain Injury, Concussion, Neuro-Ophthalmology, Saccadic Eye Movements
Interventions
Binocular ophthalmic neurodiagnostic device
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Waukee, Iowa
Recruiting No phase listed Observational Accepts healthy volunteers

Perinatal Autism Genetics and Epigenetics Study

NCT07738003
Conditions
Autism Disorders and Maternal Stress, Development Delay, Prenatal Stress, Social Behavior
Interventions
Change in child's DNA methylation, Early social experience, Perinatal stress, Polygenic risk scores for social communication and repetitive behavior
Genetic · Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
0 Years to 50 Years
Enrollment
7,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Healthy Volunteer
Interventions
ABBV-859, Placebo for ABBV-859
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Anaheim, California • Grayslake, Illinois
Recruiting No phase listed Observational Accepts healthy volunteers

Method Comparison of Intelligent Fingerprinting Drug Screening System

NCT07650136
Conditions
Drug Abuse Illicit
Interventions
Not listed
Lead sponsor
Intelligent Bio Solutions Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Marlton, New Jersey
Conditions
Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphoid Leukemia, Leukemia, Lymphoblastic Lymphoma
Interventions
Exercises
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
6 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Diabetes Mellitus, Type 2
Interventions
AMG 127, Placebo
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Lake Forest, California • Aventura, Florida
Conditions
Early Childhood, Parenting, Prevention, Program Implementation
Interventions
ezParent
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining an Intervention to Reduce High School Drinking

NCT07086508
Conditions
Adolescent Alcohol Use, Drinking, Teen, Underage Drinking
Interventions
e-CHECKUP TO GO (eCTG), e-Parent Intervention
Behavioral
Lead sponsor
Binghamton University
Other
Eligibility
15 Years to 65 Years
Enrollment
2,532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Binghamton, New York
Recruiting No phase listed Observational Accepts healthy volunteers

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

NCT06096688
Conditions
Colorectal Cancer, Endometrial Cancer, Hereditary Cancer Syndromes
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
1,120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

A Stepped Care Approach to Treating Dental Fear

NCT06024395
Conditions
Dental Fear
Interventions
A stepped-care approach to the treatment of dental fear; Dental Fearless
Behavioral
Lead sponsor
New York University
Other
Eligibility
13 Years to 99 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Retina is a Marker for Cerebrovascular Heath

NCT04753970
Conditions
Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, Cerebral Microbleeding, Cerebral Small Vessel Diseases, Sporadic White Matter Disease
Interventions
Cilostazol
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2030
U.S. locations
1
States / cities
Jacksonville, Florida