Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 13, 2026, 12:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5038
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 253–264 of 5,038 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Recruiting Not applicable Interventional Accepts healthy volunteers

Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines

NCT04595422
Conditions
Lung Carcinoma
Interventions
Educational Intervention, Questionnaire Administration, Survey Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Cardiometabolic Health
Interventions
Animal-Based Protein Smoothie, Plant-Based Protein Smoothie, Plant-Based Protein Smoothie with Leucine
Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners

NCT02596490
Conditions
Lung Cancer
Interventions
Questionnaires, Meditation and Discussion Sessions, Cancer-Related Discussion Program
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
2
States / cities
Houston, Texas
Conditions
Esophageal Carcinoma, Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Interventions
Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration, Yoga
Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Houston, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

Biomarkers in Friedreich's Ataxia

NCT02497534
Conditions
Friedreich's Ataxia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
6 Years to 70 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
EBV, Epstein-Barr Virus Infection, Infectious Mononucleosis, Mono
Interventions
EBV gp350-ferritin vaccine with ALFQ adjuvant, EBV gH/gL/gp42-ferritin nanoparticle vaccine with ALFQ adjuvant
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 29 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Thrombosis and Inflammation in Vessels Initiative (TIVI)

NCT06552767
Conditions
Cardiovascular Diseases, Vascular Diseases
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
5 Years to 100 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2034
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Wake Forest Alzheimer's Disease Clinical Core

NCT03140865
Conditions
Alzheimer's Disease, Mild Cognitive Impairment, Prediabetic State
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
850 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2031
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

NCT06373289
Conditions
Bronchopulmonary Dysplasia, Pulmonary Hypertension
Interventions
higher oxygen saturation target using Nellcor pulse oximetry sensors, lower oxygen saturation target using Nellcor pulse oximetry sensors
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Month to 5 Months
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Birmingham, Alabama • New Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

Olfactory Transcranial Focused Ultrasound

NCT07658365
Conditions
Healthy, Olfaction
Interventions
transcranial focused ultrasound (tFUS)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Entire-body PET Scans for Multiple Sclerosis

NCT04390009
Conditions
Multiple Sclerosis
Interventions
Entire-body PET-CT scans, Amyvid radiopharmaceutical
Diagnostic Test · Drug
Lead sponsor
Brain Health Alliance
Other
Eligibility
25 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Ladera Ranch, California
Recruiting No phase listed Observational Accepts healthy volunteers

Masticatory Muscle Activity Using a 24-Hour Wearable Device

NCT07861906
Conditions
Chronic Masticatory Myofascial Pain
Interventions
Not listed
Lead sponsor
Midwestern University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Downers Grove, Illinois