Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 2, 2026, 11:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

5041

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Recruiting

The default view starts with recruiting studies because those are usually the most actionable.

Current order

Live official records

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Conditions: Alcohol Use Disorder
Interventions: Not listed
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 475 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Tuberculosis (TB), Tuberculosis Infection, Latent, HIV (Human Immunodeficiency Virus)
Interventions: Mobile chest radiography for tuberculosis screening; Diagnostic Test
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Healthy Volunteers
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 3 Years to 80 Years
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2043
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Aging
Interventions: Not listed
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 55 Years to 110 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Metabolic Disease, Obesity, Li-Fraumeni Syndrome, Cardiomyopathy, Atherosclerosis, Inflammatory Disease
Interventions: NSR IDE-MRI: Research pulse sequences; Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 1 Year to 100 Years
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2010
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Bethesda, Maryland

Conditions: Diabetes Mellitus, Type 2, Obesity
Interventions: Mobile health application; Other
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: San Diego, California

Conditions: Mycobacterium Infections
Interventions: Clofazimine; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: Up to 100 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Costello Syndrome, Noonan Syndrome, Cardiofaciocutaneous Syndrome, Legius Syndrome, Capillary Arteriovenous Malformation Syndrome, RASopathy
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 1 Month to 99 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2035
U.S. locations: 2
States / cities: Bethesda, Maryland • Rockville, Maryland

Conditions: Alcohol Use Disorder
Interventions: Evaluate the effects of Environmental Enrichment (EE) on alcohol consumption; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid Use Disorder, OAT
Interventions: [11C]OMAR; Drug
Lead sponsor: Yale University; Other
Eligibility: 25 Years to 65 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cystic Fibrosis, Sickle Cell Disease, SARS CoV 2 Infection
Interventions: Exercise; Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 10 Years to 17 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Irvine, California

Conditions: Normal Volunteers
Interventions: Not listed
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 18 Years to 99 Years
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Healthy volunteer clinical trials in the U.S.

Filter healthy volunteer studies

Live official records

Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)

Screening With Portable X-rays for Rapid Recognition of TB

Sample Collection From Healthy Volunteers for Assay Optimization

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

Study of Mycobacterial Infections

Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

Environment and Alcohol: A Pilot Study

Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder

Exercise in Child Health

Tissue Procurement for Biomedical Research