Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 10:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5021
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 613–624 of 5,021 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Conditions
Healthy Volunteers
Interventions
INS1033, Placebo
Drug
Lead sponsor
Insmed Incorporated
Industry
Eligibility
18 Years to 50 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Recruiting Not applicable Interventional Accepts healthy volunteers

Modulating Movement Intention Via Cortical Stimulation

NCT03233399
Conditions
Seizures, Seizure Disorder, Psychogenic Movement Disorder
Interventions
Sham TMS3 stimulation, rTMS of left or right angular gyrus (AG) or frontal cortex (FC), Anodal tDCS of left or right AG or FC
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
D. Walter Wray
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Astigmatism
Interventions
Daily disposable contact lenses for astigmatism
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting No phase listed Observational Accepts healthy volunteers

Comparison of ALD, NASH, and Healthy Control Patients

NCT03224949
Conditions
ALD - Alcoholic Liver Disease
Interventions
Blood draw
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Flexible Conductive Hearing Aids

NCT07222202
Conditions
Conductive Hearing Loss
Interventions
flexible conductive hearing aid
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
6 Months to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-nutritive Sweeteners in Inflammatory Bowel Disease

NCT07769437
Conditions
Inflamatory Bowel Disease, Crohn Disease (CD)
Interventions
Sucralose (non-nutritive sweetener)
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
3
States / cities
Chagrin Falls, Ohio • Cleveland, Ohio • Westlake, Ohio
Recruiting Phase 1 Interventional Accepts healthy volunteers

Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors

NCT06819189
Conditions
Healthy Volunteer
Interventions
Ethanol
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
Interventions
Best Practice, Educational Intervention, Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Attention Deficit Hyperactivity Disorder Combined
Interventions
Methylphenidate, Placebo
Drug
Lead sponsor
Donald Gilbert, MD, MS, FAAN, FAAP
Other
Eligibility
8 Years to 12 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Cincinnati, Ohio
Conditions
Chronic Weight Management
Interventions
ASC35 Injection B, for subcutaneous use, ASC35 Placebo Injection B, for subcutaneous use, Tirzepatide
Drug
Lead sponsor
Ascletis Pharma (China) Co., Limited
Industry
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Healthy Male Participants
Interventions
Vimseltinib, Dabigatran
Drug
Lead sponsor
Deciphera Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Overland Park, Kansas